Catalog No.
AHG51601
Biological activity
Measured by its ability to inhibit Anti-CD3-induced proliferation of jurkat cells. The ED50 for this effect is 3.35-13.4 ng/mL.
Expression system
Mammalian Cells
Species
Homo sapiens (Human)
Protein length
Ala27-Arg242
Nature
Recombinant
Endotoxin level
<0.1 EU/μg of the protein by the LAL method.
Purity
>90% as determined by SDS-PAGE.
Accession
Q13410
Applications
Bioactivity, ELISA, Immunogen, SDS-PAGE, WB
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
BTN1A1, BTN, Butyrophilin subfamily 1 member A1, BT
Plasma proteins and different onset subtype of COPD: Proteome-wide Mendelian randomization study and co-localization analyses., PMID:40355193
DCMS analysis revealed differential selection signatures in the transboundary Sahiwal cattle for major economic traits., PMID:40325078
Production of platelets in vitro in functionalised 3-dimensional scaffolds mimicking the bone marrow niche., PMID:40270202
Exploring new drug treatment targets for immune related bone diseases using a multi omics joint analysis strategy., PMID:40148470
Multi-omic biomarkers associated with multiple sclerosis: from Mendelian randomization to drug prediction., PMID:40108295
Genomic Tools for Medicinal Properties of Goat Milk for Cosmetic and Health Benefits: A Narrative Review., PMID:39940662
Genetic and Plasma Proteomic Approaches to Identify Therapeutic Targets for Graves' Disease and Graves' Ophthalmopathy., PMID:39935908
The Effects of trans-10, cis-12 Conjugated Linoleic Acid on the Production Performance of Dairy Cows and the Expression and Transcription Regulation of Lipid Metabolism-Related Genes in Bovine Mammary Epithelial Cells., PMID:39130591
Novel drug resistance mechanisms and drug targets in BRAF-mutated peritoneal metastasis from colorectal cancer., PMID:38982444
Neonatal enteroids absorb extracellular vesicles from human milk-fed infant digestive fluid., PMID:38602306
BTN1A1 is a novel immune checkpoint mutually exclusive to PD-L1., PMID:38485289
Effects of antioxidant vitamins (A, D, E) and trace elements (Cu, Mn, Se, Zn) administration on gene expression, metabolic, antioxidants and immunological profiles during transition period in dromedary camels., PMID:38481237
Simple methods for measuring milk exosomes using fluorescent compound GIF-2250/2276., PMID:38219490
Neonatal enteroids absorb extracellular vesicles from human milk-fed infant digestive fluid., PMID:38187651
Bovine Milk Proteome: Milk Fat Globule Membrane Protein Is the Most Sensitive Fraction in Response to High Somatic Cell Count., PMID:37816197
Analysis of a new therapeutic target and construction of a prognostic model for breast cancer based on ferroptosis genes., PMID:37643511
[Effects of auricular thumbtack needle on lactation function and TDP-43/Btn1A1/XDH pathway in primiparous women with cesarean section]., PMID:37429656
Genome-wide identification and skin expression of immunoglobulin superfamily in discus fish (Symphysodon aequifasciatus) reveal common genes associated with vertebrate lactation., PMID:36775217
Patient-Derived Extracellular Vesicles Proteins as New Biomarkers in Multiple Myeloma - A Real-World Study., PMID:35800053
High resolution melt curve analysis identifies a novel SNP (G21A) in butyrophilin gene having significant association with milk production traits in Holstein Friesian crossbreds of Kerala., PMID:35189067
LPIN1 promotes triglycerides synthesis and is transcriptionally regulated by PPARG in buffalo mammary epithelial cells., PMID:35149744
Occludin is a target of Src kinase and promotes lipid secretion by binding to BTN1a1 and XOR., PMID:35041644
The butyrophilin 1a1 knockout mouse revisited: Ablation of Btn1a1 leads to concurrent cell death and renewal in the mammary epithelium during lactation., PMID:34938960
Transcriptional profiling of buffalo mammary gland with different milk fat contents., PMID:34352300
The extracellular region of bovine milk butyrophilin exhibits closer structural similarity to human myelin oligodendrocyte glycoprotein than to immunological BTN family receptors., PMID:34342946
A Candidate Gene Association Study for Economically Important Traits in Czech Dairy Goat Breeds., PMID:34208578
Peroxisome proliferator-activated receptor gamma regulates genes involved in milk fat synthesis in mammary epithelial cells of water buffalo., PMID:33682250
Knockout of butyrophilin subfamily 1 member A1 (BTN1A1) alters lipid droplet formation and phospholipid composition in bovine mammary epithelial cells., PMID:32637097
Identification and Characterization of the Lactating Mouse Mammary Gland Citrullinome., PMID:32290104
Postprandial transfer of colostral extracellular vesicles and their protein and miRNA cargo in neonatal calves., PMID:32109241
TDP-43 facilitates milk lipid secretion by post-transcriptional regulation of Btn1a1 and Xdh., PMID:31953403
Protein digestion properties of Xinong Saanen goat colostrum and mature milk using in vitro digestion model., PMID:31180140
Milk-derived mammary epithelial cells as non-invasive source to define stage-specific abundance of milk protein and fat synthesis transcripts in native Sahiwal cows and Murrah buffaloes., PMID:30863690
High expression of cell death-inducing DFFA-like effector a (CIDEA) promotes milk fat content in dairy cows with clinical ketosis., PMID:30594378
Precision medicine validation: identifying the MYBPC3 A31P variant with whole-genome sequencing in two Maine Coon cats with hypertrophic cardiomyopathy., PMID:30558461
Transcriptional profiling of swine mammary gland during the transition from colostrogenesis to lactogenesis using RNA sequencing., PMID:29724161
trans-10,cis-12-Conjugated Linoleic Acid Affects Expression of Lipogenic Genes in Mammary Glands of Lactating Dairy Goats., PMID:29019657
Characterisation of gene expression related to milk fat synthesis in the mammary tissue of lactating yaks., PMID:28831970
Altered expression of Butyrophilin (BTN) and BTN-like (BTNL) genes in intestinal inflammation and colon cancer., PMID:27957327
Transcriptome expression analysis of candidate milk genes affecting cheese-related traits in 2 sheep breeds., PMID:27179853
Milk fat globule is an alternative to mammary epithelial cells for gene expression analysis in buffalo., PMID:27032540
Analysis of human breast milk cells: gene expression profiles during pregnancy, lactation, involution, and mastitic infection., PMID:26909879
Matrix-based three-dimensional culture of buffalo mammary epithelial cells showed higher induction of genes related to milk protein and fatty acid metabolism., PMID:26503422
The effect of heat stress on gene expression and synthesis of heat-shock and milk proteins in bovine mammary epithelial cells., PMID:26467738
Adipose triglyceride lipase regulates lipid metabolism in dairy goat mammary epithelial cells., PMID:25307872
Bovine mammary epithelial cell cultures for the study of mammary gland functions., PMID:24234512
A test of current models for the mechanism of milk-lipid droplet secretion., PMID:23738536
Isolation, characterization, and EGFP expression in the buffalo (Bubalus bubalis) mammary gland epithelial cell line., PMID:23180034
Akt1 is essential for postnatal mammary gland development, function, and the expression of Btn1a1., PMID:21915327
Evaluating markers in selected genes for association with functional longevity of dairy cattle., PMID:21392379
For research use only. Not for human or drug use.
