Catalog No.
YHC06301
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ser87-Thr211
Predicted molecular weight
16.62 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P04085
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Platelet-derived growth factor alpha polypeptide, Platelet-derived growth factor subunit A, Platelet-derived growth factor A chain, PDGF subunit A, PDGFA, PDGF-1, PDGF1
Macrophage depletion in male mice impairs extraction socket healing by disrupting bone regeneration and tissue repair., PMID:40441056
Biejia ruangan tablet alleviated liver fibrosis in murine models by hindering the crosstalk between hepatic stellate cells and M2-like macrophages through PDGF-AA/PI3K/AKT pathway., PMID:40414578
Platelet-Derived PDGF-A Disrupts Blood-Brain Barrier Integrity in Ischemic Stroke., PMID:40371467
Increased expression of PDGFA and RAF1 in Tumor-derived exosomes in human colorectal cancer., PMID:40235336
Effects of the continuous theta-burst stimulation on the levels of peripheral blood neuroplasticity biomarkers in people with obsessive-compulsive disorder: Findings from an open-label trial., PMID:40086220
KLF5 silencing restrains proliferation, invasion, migration and angiogenesis of gallbladder carcinoma cells by transcriptional regulation of PDGFA., PMID:39704786
Platelet-Derived Growth Factor Subunit A Strengthens the Neurovascular Unit and Inhibits Retinal Vascular Regression Under Hyperoxic Conditions., PMID:39684657
The effect of platelet-derived growth factor-aa (PDGFA) conjugated with low-molecular-weight protamine (LMWP) on hair loss improvement effect., PMID:39647454
[Growth factors PDGF-AA, PDGF-BB and BDNF as potential differentiating biomarkers of unipolar and bipolar depression]., PMID:39435785
Increased Expression of PDGFA Is Associated With Poor Prognosis and Immune Infiltration in Head and Neck Squamous Cell Carcinoma., PMID:39295197
Changes in plasma concentrations of novel vascular and inflammatory biomarkers in obstructive sleep apnea patients pre- and post-stroke., PMID:38805859
The relationships of platelet-derived growth factor, microvascular proliferation, and tumor cell proliferation in canine high-grade oligodendrogliomas: Immunohistochemistry of 45 tumors and an AFOB-01 xenograft mouse model., PMID:38577818
Curcumin prevents high glucose-induced stimulatory effects of renal cell secretome on fibroblast activation via mitigating intracellular free radicals and TGF-β secretion., PMID:38569274
Identification of PDGFA as a Neutrophil-related Biomarker Linked to the Advancement of Diabetic Retinopathy through Integrated Bioinformatics Analysis., PMID:38504565
Effective Treatment of Anlotinib Combined With Chemotherapy in Children With Desmoplastic Small Round Cell Tumor: A Case Series in a Single-center and Literature Review., PMID:38408140
Effects of pulsed electrical stimulation on α-smooth muscle actin and type I collagen expression in human dermal fibroblasts., PMID:38341279
PDGF-AA guides cell crosstalk between human dental pulp stem cells in vitro via the PDGFR-α/PI3K/Akt axis., PMID:38332717
Protein-Protein interactive networks identified in bronchoalveolar lavage of severe compared to nonsevere asthma., PMID:38253462
PDGF-AA loaded photo-crosslinked chitosan-based hydrogel for promoting wound healing., PMID:38161023
Tryptase-Positive Mast Cells Promote Adipose Fibrosis in Secondary Lymphedema through PDGF., PMID:37886950
Immune responses of patients on maintenance hemodialysis after infection by SARS-CoV-2: a prospective observational cohort study., PMID:37674148
MTHFR C677T Polymorphism, Plasma Homocysteine, and PDGF-AA Levels and Transcranial Doppler Velocity in Children With Sickle Cell Disease., PMID:37260067
Mitogen-induced defective mitosis transforms neural progenitor cells., PMID:37186014
Brain heterotopia formation by ciliopathic breakdown of neuroepithelial and blood-cerebrospinal fluid barriers., PMID:36623505
Molecular profile and peripheral markers of neurodegeneration in patients with Niemann-Pick type C: Decrease in Plasminogen Activator Inhibitor type 1 and Platelet-Derived Growth Factor type AA., PMID:36608914
Platelet-derived growth factor AA-modified electrospun fibers promote tendon healing., PMID:36411499
PDGF-AA activates AKT and ERK signaling for testicular interstitial Leydig cell growth via primary cilia., PMID:36306470
Effects of uteroplacental insufficiency on growth-restricted rats with altered lung development: A metabolomic analysis., PMID:36160795
3D Living Dressing Improves Healing and Modulates Immune Response in a Thermal Injury Model., PMID:35658609
Hyperbaric Oxygen Improves the Survival and Angiogenesis of Fat Grafts after Autologous Fat Transplantation., PMID:35647192
Platelet-derived growth factor-AA promotes placental choriocarcinoma JAR cell proliferation via primary cilia., PMID:35361391
[The Role of Platelet-Derived Growth Factor-AA in the Pathogenesis and Development of Osteoarthritis]., PMID:35332741
lncRNA H22954 Inhibits Angiogenesis in Acute Myeloid Leukemia through a PDGFA-dependent Mechanism., PMID:35319391
PDGF-AA promotes gap junction intercellular communication in chondrocytes via the PI3K/Akt pathway., PMID:35152816
RhoA/ROCK2 signalling is enhanced by PDGF-AA in fibro-adipogenic progenitor cells: implications for Duchenne muscular dystrophy., PMID:35132805
EPHA2 mediates PDGFA activity and functions together with PDGFRA as prognostic marker and therapeutic target in glioblastoma., PMID:35105853
GSDMB is increased in IBD and regulates epithelial restitution/repair independent of pyroptosis., PMID:35021065
Expression and function of PDGF-C in development and stem cells., PMID:34847773
PDGF-AA promotes cell-to-cell communication in osteocytes through PI3K/Akt signaling pathway., PMID:34586354
Variant PCGF1-PRC1 links PRC2 recruitment with differentiation-associated transcriptional inactivation at target genes., PMID:34504070
Platelet derived growth factor-A (Pdgf-a) gene transfer modulates scar composition and improves left ventricular function after myocardial infarction., PMID:34265313
The cancer angiogenesis co-culture assay: In vitro quantification of the angiogenic potential of tumoroids., PMID:34234354
IGFBP2 Is a Potential Master Regulator Driving the Dysregulated Gene Network Responsible for Short Survival in Glioblastoma Multiforme., PMID:34211498
Bisphenol analogs AF and S: Effects on cell status and production of angiogenesis-related factors by COV434 human granulosa cell line., PMID:34174261
Caveolin-1 expression predicts favourable outcome and correlates with PDGFRA mutations in gastrointestinal stromal tumours (GISTs)., PMID:34155091
KIT Mutation in Gastric Gastrointestinal Stromal Tumor in a Patient With Familial Paraganglioma Syndrome Type 4., PMID:34095481
High expression of PDGFA predicts poor prognosis of esophageal squamous cell carcinoma., PMID:34011067
Microglial neuropilin-1 promotes oligodendrocyte expansion during development and remyelination by trans-activating platelet-derived growth factor receptor., PMID:33859199
Triple growth factor delivery promotes functional bone regeneration following composite musculoskeletal trauma., PMID:33823326
Embryonic protein NODAL regulates the breast tumor microenvironment by reprogramming cancer-derived secretomes., PMID:33784590
For research use only. Not for human or drug use.
