Catalog No.
PXX06701
Species reactivity
Treponema pallidum (strain Nichols)
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Treponema pallidum TPP17 (Cys22-Lys156).
Applications
ELISA, IHC, WB
Target
17 kDa lipoprotein, tpp17, TP_0435, Treponema Pallidum (TP,Syphilis)
Concentration
0.69 mg/ml
Purification
Antigen affinity purification.
Accession
P29722
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Note
For research use only.
Lipid modification of the 17-kilodalton membrane immunogen of Treponema pallidum determines macrophage activation as well as amphiphilicity., PMID:8454324
Activation of human monocytic cells by Treponema pallidum and Borrelia burgdorferi lipoproteins and synthetic lipopeptides proceeds via a pathway distinct from that of lipopolysaccharide but involves the transcriptional activator NF-kappa B., PMID:8751937
Evidence that immunization with TP0751, a bipartite Treponema pallidum lipoprotein with an intrinsically disordered region and lipocalin fold, fails to protect in the rabbit model of experimental syphilis., PMID:32936831
Development of an automated processing platform based on luciferase fused TPP17 to detect specific Treponema pallidum antibody in clinical serum with high sensitivity and rapidity., PMID:39537062
For research use only. Not for human or drug use.
