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Anti-HSV-2/HHV-2 gC/UL44 Polyclonal Antibody

Catalog #:   PVV41301 Specific References (50) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: ELISA, IHC, WB
Accession: Q89730
Overview

Catalog No.

PVV41301

Species reactivity

Human herpesvirus 2 (strain HG52) (HHV-2) (Human herpes simplex virus 2)

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant HSV-2/HHV-2 gC/UL44 (Ser28-Gly447).

Target

gC, UL44, Envelope glycoprotein C

Purification

Antigen affinity purification.

Accession

Q89730

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Data Image
  • Western Blot
    Recombinant Protein lysates were subjected to SDS PAGE followed by western blot with gC/UL44/Envelope glycoprotein C antibody (PVV41301) at 1 µg/ml.

    Lane 1: Recombinant Protein

    Second Ab: Goat Anti-Rabbit IgG H&L Polyclonal antibody, HRP (PTB96431) at 0.1 μg/mL.

    Predict MW: HSV-2/HHV-2
    Observed MW:
References

Contributions of the Four Essential Entry Glycoproteins to HSV-1 Tropism and the Selection of Entry Routes., PMID:33653890

An HSV-2 nucleoside-modified mRNA genital herpes vaccine containing glycoproteins gC, gD, and gE protects mice against HSV-1 genital lesions and latent infection., PMID:32716975

Utility of HSV Serology for Chronic Corneal Pathology., PMID:31306215

The herpevac trial for women: Sequence analysis of glycoproteins from viruses obtained from infected subjects., PMID:28448558

Linear Multiepitope (Glyco)peptides for Type-Specific Serology of Herpes Simplex Virus (HSV) Infections., PMID:28238255

Patient-Specific Neutralizing Antibody Responses to Herpes Simplex Virus Are Attributed to Epitopes on gD, gB, or Both and Can Be Type Specific., PMID:26109729

Dissection of the antibody response against herpes simplex virus glycoproteins in naturally infected humans., PMID:25142599

Seroprevalence of herpes simplex virus type 1 and type 2 in Thuringia, Germany, 1999 to 2006., PMID:22085620

Immunization with a vaccine combining herpes simplex virus 2 (HSV-2) glycoprotein C (gC) and gD subunits improves the protection of dorsal root ganglia in mice and reduces the frequency of recurrent vaginal shedding of HSV-2 DNA in guinea pigs compared to immunization with gD alone., PMID:21813597

The glycoproteins C and G are equivalent target antigens for the determination of herpes simplex virus type 1-specific antibodies., PMID:20171247

Dendritic cells mediate herpes simplex virus infection and transmission through the C-type lectin DC-SIGN., PMID:18796707

Impact of a community sexually transmitted infection/HIV intervention project on female sex workers in five border provinces of Vietnam., PMID:17327262

Herpes simplex virus type 1 and 2 glycoprotein C prevents complement-mediated neutralization induced by natural immunoglobulin M antibody., PMID:16571820

Production of herpes B virus recombinant glycoproteins and evaluation of their diagnostic potential., PMID:15695655

CD4(+) T-cell responses to herpes simplex virus type 2 (HSV-2) glycoprotein G are type specific and differ in symptomatic and asymptomatic HSV-2-infected individuals., PMID:15269352

Characterization of B virus glycoprotein antibodies induced by DNA immunization., PMID:12417944

Differentiation of Herpes simplex virus types 1 and 2 in sera of patients with HSV central nervous system infections by type-specific enzyme-linked immunosorbent assay., PMID:11798261

Immunity induced by DNA immunization with herpes simplex virus type 2 glycoproteins B and C., PMID:10580201

3-Hydroxyphthaloyl beta-lactoglobulin. III. Antiviral activity against herpesviruses., PMID:9875389

Incidence of HIV and sexually transmitted diseases (STD) in a cohort of HIV-negative men who have sex with men (MSM)., PMID:9814873

Mapping of linear antigenic determinants on glycoprotein C of herpes simplex virus type 1 and type 2 recognized by human serum immunoglobulin G antibodies., PMID:9661836

Limited variability of glycoprotein gene sequences and neutralizing targets in herpes simplex virus type 2 isolates and stability on passage in cell culture., PMID:9652417

Expression and Purification of Secreted Forms of HSV Glycoproteins from Baculovirus-Infected Insect Cells., PMID:21374226

Monoclonal antibodies to the distinct antigenic sites on glycoproteins C and B and their protective abilities in herpes simplex virus infection., PMID:9199708

Cervical cancer and herpes simplex virus type 2: case-control studies in Spain and Colombia, with special reference to immunoglobulin-G sub-classes., PMID:7829255

An evaluation of a hemagglutination-inhibition test for the detection of antibodies to herpes simplex virus type 1., PMID:15566801

Protein-specific cervical antibody responses to primary genital herpes simplex virus type 2 infections., PMID:8014499

[Biological properties of hemagglutinin of herpes simplex virus type 1]., PMID:8175105

A rapid simple in situ hybridization method for herpes simplex virus employing a synthetic biotin-labeled oligonucleotide probe: a comparison with immunohistochemical methods for HSV detection., PMID:8189321

Herpes simplex virus glycoprotein C: molecular mimicry of complement regulatory proteins by a viral protein., PMID:8406590

Genetic analysis of type-specific antigenic determinants of herpes simplex virus glycoprotein C., PMID:1378512

Structural basis of C3b binding by glycoprotein C of herpes simplex virus., PMID:1602532

Factors influencing the interaction of herpes simplex virus glycoprotein C with the third component of complement., PMID:1333754

A related epitope is consistently present on glycoprotein C of herpes simplex virus type 1 and 2., PMID:1719785

Type-common and type-specific monoclonal antibodies to herpes simplex virus types 1 and 2., PMID:1681713

Inducible expression of herpes simplex virus type 1 glycoprotein C in NIH 3T3 cells., PMID:1965287

Serologic type conversion of a herpes simplex virus type 1 (HSV-1) to an HSV-2 epitope caused by a single amino acid substitution in glycoprotein C., PMID:2164613

Localization on the herpes simplex virus type 1 genome of a region encoding proteins involved in adsorption to the cellular receptor., PMID:2154609

Chronic-dose acyclovir to suppress frequently recurring genital herpes simplex virus infection: effect on antibody response to herpes simplex virus type 2 proteins., PMID:2848900

C3b receptor activity on transfected cells expressing glycoprotein C of herpes simplex virus types 1 and 2., PMID:2845122

Induction of Fc and C3b receptors on rabbit corneal cells by herpes simplex virus., PMID:3417420

Differential effect of systemic acyclovir treatment of genital HSV-2 infections on antibody responses to individual HSV-2 proteins., PMID:2835427

Zwitterionic detergent solubilisation of HSV-1 surface antigens., PMID:2831853

Typing of herpes simplex virus types 1 and 2 by immunoblotting analysis using polyclonal antisera to herpes simplex virus glycoproteins., PMID:2828400

Herpes simplex virus glycoproteins gC-1 and gC-2 bind to the third component of complement and provide protection against complement-mediated neutralization of viral infectivity., PMID:2824652

Antigenic cross-reactions among herpes simplex virus types 1 and 2, Epstein-Barr virus, and cytomegalovirus., PMID:3029407

Detection of asymptomatic herpes simplex virus infections after vaccination., PMID:3806788

Binding of complement component C3b to glycoprotein gC of herpes simplex virus type 1: mapping of gC-binding sites and demonstration of conserved C3b binding in low-passage clinical isolates., PMID:3021981

Characterization and immunogenicity of HSV-1 antigens obtained following zwitterionic detergent treatment., PMID:3020821

Expression of herpes simplex virus glycoproteins in polarized epithelial cells., PMID:3009881

Datasheet
$ 170
Product specifications
50 μg 170 100 μg 280

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For research use only. Not for human or drug use.

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Anti-HSV-2/HHV-2 gC/UL44 Polyclonal Antibody [PVV41301]
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