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Anti-Human BMP6 Antibody (SAA0425), PE

Catalog #:   FHD49512 Specific References (50) DATASHEET
Host species: Mouse
Isotype: IgG2a, kappa
Applications: ELISA, FCM
Accession: P22004
Overview

Catalog No.

FHD49512

Species reactivity

Human

Host species

Mouse

Isotype

IgG2a, kappa

Clonality

Monoclonal

Conjugation

PE

Applications

ELISA, FCM

Target

VG-1-R, VG-1-related protein, Bone morphogenetic protein 6, VGR-1, BMP-6, VGR, BMP6

Concentration

0.5 mg/ml

Endotoxin level

Please contact with the lab for this information.

Accession

P22004

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300.

Stability and Storage

Store at 4°C for 12 months. Protect from light. Do not freeze.

Clone ID

SAA0425

Note

For research use only.

Data Image
References

Iron overload induces BMP6 expression in the liver but not in the duodenum., PMID:20952515

Healing of tooth extraction sockets in the streptozotocin diabetic rat model: Induction of cartilage by BMP-6., PMID:20969540

The bone morphogenetic protein-hepcidin axis as a therapeutic target in inflammatory bowel disease., PMID:21351217

Macrophages induce neuroendocrine differentiation of prostate cancer cells via BMP6-IL6 Loop., PMID:21374653

Circulating bone morphogenetic protein 1-3 isoform increases renal fibrosis., PMID:21415150

Bone morphogenetic protein 6-induced interleukin-1β expression in macrophages requires PU.1/Smad1 interaction., PMID:21571370

Regulation of TMPRSS6 by BMP6 and iron in human cells and mice., PMID:21622652

Bone morphogenetic proteins inhibit CD40L/IL-21-induced Ig production in human B cells: differential effects of BMP-6 and BMP-7., PMID:21898381

Chondrogenesis from umbilical cord blood cells stimulated with BMP-2 and BMP-6., PMID:22238025

Targeting the hepcidin-ferroportin axis to develop new treatment strategies for anemia of chronic disease and anemia of inflammation., PMID:22290531

Regulatory role of kit ligand-c-kit interaction and oocyte factors in steroidogenesis by rat granulosa cells., PMID:22366471

An in vivo role of bone morphogenetic protein-6 in aldosterone production by rat adrenal gland., PMID:22538126

Bone morphogenetic protein-6 induces castration resistance in prostate cancer cells through tumor infiltrating macrophages., PMID:23710822

Association of bone morphogenetic protein 6 with exocrine gland dysfunction in patients with Sjögren's syndrome and in mice., PMID:23982860

Mechanism of pro-tumorigenic effect of BMP-6: neovascularization involving tumor-associated macrophages and IL-1a., PMID:24185914

The role of bone morphogenetic protein 6 in accumulation and regulation of neutrophils in the human ovary., PMID:24406789

E-Cadherin and EpCAM expression by NSCLC tumour cells associate with normal fibroblast activation through a pathway initiated by integrin αvβ6 and maintained through TGFβ signalling., PMID:24488011

Quercetin prevents ethanol-induced iron overload by regulating hepcidin through the BMP6/SMAD4 signaling pathway., PMID:24746831

Low-intensity pulsed ultrasound induces osteogenic differentiation of human periodontal ligament cells through activation of bone morphogenetic protein-smad signaling., PMID:24764342

Hepcidin antagonists for potential treatments of disorders with hepcidin excess., PMID:24808863

Stromal TGF-β signaling induces AR activation in prostate cancer., PMID:25333263

KGF and BMP-6 intervene in cellular reprogramming and in mesenchymal-epithelial transition (MET) of 3T3L1 mouse adipose cells., PMID:25492426

Peripheral Blood Mononuclear Cells Enhance Cartilage Repair in in vivo Osteochondral Defect Model., PMID:26252391

Increased hepcidin in transferrin-treated thalassemic mice correlates with increased liver BMP2 expression and decreased hepatocyte ERK activation., PMID:26635037

Effect of Erythropoietin, Iron Deficiency and Iron Overload on Liver Matriptase-2 (TMPRSS6) Protein Content in Mice and Rats., PMID:26845567

Increased Retinal Expression of the Pro-Angiogenic Receptor GPR91 via BMP6 in a Mouse Model of Juvenile Hemochromatosis., PMID:27046124

Effects of Anti-repulsive Guidance Molecule C (RGMc/Hemojuvelin) Antibody on Hepcidin and Iron in Mouse Liver and Tumor Xenografts., PMID:28203489

BMP-7 induces apoptosis in human germinal center B cells and is influenced by TGF-β receptor type I ALK5., PMID:28489883

The importance of BMP6 marker within the process of epithelial-mesenchymal transition in the pleomorphic adenoma of the salivary gland., PMID:28523310

Bone morphogenetic protein 2 controls iron homeostasis in mice independent of Bmp6., PMID:28815688

Bone Morphogenetic Protein 6 Polymorphisms are Associated With Systemic Lupus Erythematosus Susceptibility in the Korean Population., PMID:30874244

Erythroferrone inhibits the induction of hepcidin by BMP6., PMID:30097509

Cyp1b1 expression impacts the angiogenic and inflammatory properties of liver sinusoidal endothelial cells., PMID:30372497

Targeting the hepcidin-ferroportin pathway in anaemia of chronic kidney disease., PMID:30677788

Reduction of BMP6-induced bone formation by calcium phosphate in wild-type compared with nude mice., PMID:30815997

Antibodies against the erythroferrone N-terminal domain prevent hepcidin suppression and ameliorate murine thalassemia., PMID:31899794

A fully human anti-BMP6 antibody reduces the need for erythropoietin in rodent models of the anemia of chronic disease., PMID:32438400

Recombinant Human BMP6 Applied Within Autologous Blood Coagulum Accelerates Bone Healing: Randomized Controlled Trial in High Tibial Osteotomy Patients., PMID:32543706

A novel autologous bone graft substitute comprised of rhBMP6 blood coagulum as carrier tested in a randomized and controlled Phase I trial in patients with distal radial fractures., PMID:32730930

The Influence of Adalimumab and Cyclosporine A on the Expression Profile of the Genes Related to TGFβ Signaling Pathways in Keratinocyte Cells Treated with Lipopolysaccharide A., PMID:32774143

BMP6 Regulates Corneal Epithelial Cell Stratification by Coordinating Their Proliferation and Differentiation and Is Upregulated in Pterygium., PMID:32845956

Negative regulators of TGF-β1 signaling in renal fibrosis; pathological mechanisms and novel therapeutic opportunities., PMID:33480423

Adrenergic receptor behaviors of mesenchymal stem cells obtained from different tissue sources and the effect of the receptor blockade on differentiation., PMID:34323168

Sputum Cytokine Profiling in COPD: Comparison Between Stable Disease and Exacerbation., PMID:36017119

Vitiligo progression in a patient undergoing romosozumab treatment for osteoporosis., PMID:37965188

ACVR1: A Novel Therapeutic Target to Treat Anemia in Myelofibrosis., PMID:38201581

Sex as a Critical Variable in Basic and Pre-Clinical Studies of Fibrodysplasia Ossificans Progressiva., PMID:38397414

Involvement of mitogen- and stress-activated protein kinase 1 in BMP-6-induced chondrocyte differentiation., PMID:39307301

A Recombinant Antibody Against ALK2 Promotes Tissue Iron Redistribution and Contributes to Anemia Resolution in a Mouse Model of Anemia of Inflammation., PMID:39791515

Pulmonary Microvascular Endothelial Cells Support Alveolar Epithelial Growth via Bone Morphogenetic Protein 6 Secretion., PMID:40439543

Datasheet
$ 258
Product specifications
50 T 258 100 T 426

Contact Information

Order: order@antibodysystem.com

Mail: support@antibodysystem.com

Distributor list

For research use only. Not for human or drug use.

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Anti-Human BMP6 Antibody (SAA0425), PE [FHD49512]
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