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Anti-Human ERBB3/HER3 Antibody (SAA0122), PE

Catalog #:   FHD48412 Specific References (49) DATASHEET
Host species: Human
Isotype: IgG1, kappa
Applications: FCM
Accession: P21860
Overview

Catalog No.

FHD48412

Species reactivity

Human

Host species

Human

Isotype

IgG1, kappa

Clonality

Monoclonal

Conjugation

PE

Applications

FCM

Target

ERBB3, HER3, Proto-oncogene-like protein c-ErbB-3, Tyrosine kinase-type cell surface receptor HER3, Receptor tyrosine-protein kinase erbB-3

Concentration

0.5 mg/ml

Endotoxin level

Please contact with the lab for this information.

Accession

P21860

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300.

Stability and Storage

Store at 4°C for 12 months. Protect from light. Do not freeze.

Clone ID

SAA0122

Note

For research use only.

Data Image
References

Clinicopathological significance of concurrent ErbB receptor expression in human meningioma., PMID:37719042

HER-3 surface expression increases in advanced colorectal cancer representing a potential therapeutic target., PMID:37898642

The novel antibody fusion protein rhNRG1-HER3i promotes heart regeneration by enhancing NRG1-ERBB4 signaling pathway., PMID:38150867

ErbB3 Governs Endothelial Dysfunction in Hypoxia-Induced Pulmonary Hypertension., PMID:38214194

The Therapeutic Significance of HER3 in Non-small Cell Lung Cancer (NSCLC): A Review Study., PMID:38231075

ERBB3 Overexpression is Enriched in Diverse Patient Populations with Castration-sensitive Prostate Cancer and is Associated with a Unique AR Activity Signature., PMID:38306015

Targeting PI3K/AKT/mTOR and MAPK Signaling Pathways in Gastric Cancer., PMID:38339127

Translational insights and overall survival in the U31402-A-U102 study of patritumab deruxtecan (HER3-DXd) in EGFR-mutated NSCLC., PMID:38369013

Neuregulin-1 and ALS19 (ERBB4): at the crossroads of amyotrophic lateral sclerosis and cancer., PMID:38369520

Expert Consensus on the Diagnosis and Treatment of NRG1/2 Gene Fusion Solid Tumors., PMID:38414979

Molecular and Clinical Portrait of HER2-low Invasive Lobular Carcinomas., PMID:38428737

Targeting HER2/HER3 co-mutations in metastatic breast cancer: Case reports of exceptional responders to trastuzumab and pertuzumab therapy., PMID:38441358

A novel bispecific antibody drug conjugate targeting HER2 and HER3 with potent therapeutic efficacy against breast cancer., PMID:38605180

DB-1310, an ADC comprised of a novel anti-HER3 antibody conjugated to a DNA topoisomerase I inhibitor, is highly effective for the treatment of HER3-positive solid tumors., PMID:38632563

Pertuzumab Plus Trastuzumab in Patients With Biliary Tract Cancer With ERBB2/3 Alterations: Results From the Targeted Agent and Profiling Utilization Registry Study., PMID:38748939

HER3 (ERBB3) amplification in liposarcoma - a putative new therapeutic target?, PMID:38760830

Inhibition of EGFR/ErbB does not protect against C. difficile toxin B., PMID:38798529

Trans-activating mutations of the pseudokinase ERBB3., PMID:38806620

BL-B01D1, a first-in-class EGFR-HER3 bispecific antibody-drug conjugate, in patients with locally advanced or metastatic solid tumours: a first-in-human, open-label, multicentre, phase 1 study., PMID:38823410

Long road towards effective HER3 targeting in breast cancer., PMID:38885540

Patritumab deruxtecan in HER2-negative breast cancer: part B results of the window-of-opportunity SOLTI-1805 TOT-HER3 trial and biological determinants of early response., PMID:38992028

HER3 receptor and its role in the therapeutic management of metastatic breast cancer., PMID:39020378

Targeting undruggable phosphatase overcomes trastuzumab resistance by inhibiting multi-oncogenic kinases., PMID:39094301

ERBB3 targeting: A promising approach to overcoming cancer therapeutic resistance., PMID:39098760

EV20/Omomyc: A novel dual MYC/HER3 targeting immunoconjugate., PMID:39128771

Correction: The anti-HER3 (ErbB3) therapeutic antibody 9F7-F11 induces HER3 ubiquitination and degradation in tumors through JNK1/2- dependent ITCH/AIP4 activation., PMID:39392382

Leucine-Rich Alpha-2-Glycoprotein 1 Promotes Metastatic Colorectal Cancer Growth Through Human Epidermal Growth Factor Receptor 3 Signaling., PMID:39393543

Antitumor activity of PAbs generated by immunization with a novel HER3-targeting protein-based vaccine candidate in preclinical models., PMID:39479017

A review of recombinant HER3 affibodies with an effective diagnostic view of cancer cells., PMID:39485069

YAP Regulates HER3 Signaling-Driven Adaptive Resistance to RET Inhibitors in RET-Aberrant Cancers., PMID:39495173

Pre-radiation Nivolumab plus ipilimumab in patients with newly diagnosed high-grade gliomas., PMID:39572979

PlexinD1 is a driver and a therapeutic target in advanced prostate cancer., PMID:39748059

Exploring novel therapeutic targets in small bowel adenocarcinoma: insights from claudin 18.2, nectin-4, and HER3 expression analysis., PMID:39754977

CD44v, S1PR1, HER3, MET and cancer-associated amino acid transporters are promising targets for the pancreatic cancers characterized using mAb., PMID:39757718

Efficacy of Zenocutuzumab in NRG1 Fusion-Positive Cancer., PMID:39908431

Case report: Near-complete response to neratinib-based treatment in HR-positive HER2-amplified metastatic breast cancer refractory to trastuzumab deruxtecan., PMID:39931207

Human epidermal growth factor receptor 3 expression in patients with epithelial ovarian cancer: a potential target for ovarian mucinous and clear cell carcinoma., PMID:39937426

Full-length transcriptome atlas of gallbladder cancer reveals trastuzumab resistance conferred by ERBB2 alternative splicing., PMID:39948369

Systemic HER3 ligand-mimicking nanobioparticles enter the brain and reduce intracranial tumour growth., PMID:39984637

HER3-targeting Antibody-drug Conjugates Therapy for Solid Tumors: Recent Advances and Future Potentials., PMID:39995133

Uncovering potential targets for antibody-drug conjugates in the treatment of gynecologic malignancies., PMID:40046734

Emerging importance of HER3 in tumorigenesis and cancer therapy., PMID:40087402

Establishment and characterization of novel patient-derived esophageal tumoroids with long-term cultivability., PMID:40108093

Diverse ERBB2/ERBB3 Activating Alterations and Coalterations Have Implications for HER2/3-Targeted Therapies across Solid Tumors., PMID:40178042

HER3: Unmasking a twist in the tale of a previously unsuccessful therapeutic pursuit targeting a key cancer survival pathway., PMID:40290122

Ophthalmological manifestations and plasma markers of inflammation in Ebola survivors in post-treatment era., PMID:40301432

Integrated Two-Analyte Population Pharmacokinetics Model of Patritumab Deruxtecan (HER3-DXd) Monotherapy in Patients with Solid Tumors., PMID:40408047

Efficient Design of Affilin® Protein Binders for HER3., PMID:40429825

Patritumab deruxtecan induces immunogenic cell death., PMID:40458967

Datasheet
$ 292
Product specifications
50 T 292 100 T 484

Contact Information

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Distributor list

For research use only. Not for human or drug use.

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Anti-Human ERBB3/HER3 Antibody (SAA0122), PE [FHD48412]
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