Catalog No.
YHB77501
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Arg264
Predicted molecular weight
31.39 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O95863
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Protein sna, SNAI1, Zinc finger protein SNAI1, Protein snail homolog 1, SNAH
Anoikis classification of lung squamous cell carcinoma reveals correlation with clinical prognosis and immune characteristics., PMID:40515636
TGF-β induces EMT in thyroid cancer cells by regulating transcription factors., PMID:40490818
HDAC7 promotes renal cancer progression by reprogramming branched-chain amino acid metabolism., PMID:40465706
EMT induction in normal breast epithelial cells by COX2-expressing fibroblasts., PMID:40405218
Molecular mechanisms of arecoline-induced oral cancer: a network toxicology and molecular docking techniques integrated analysis., PMID:40397259
Control of Snail1 protein stability by post-translational modifications: the basis for a complex regulation of Snail1 function., PMID:40384869
Zinc finger protein 750 is a novel regulator of osteoblast differentiation and bone homeostasis by transcriptionally deactivating SNAI1 signaling., PMID:40371960
Solid stress compression enhances breast cancer cell migration through the upregulation of Interleukin-6., PMID:40371393
Identification of a Distal Enhancer That Regulates TGF-β-Induced SNAI1 Expression., PMID:40364580
[Saltwater stir-fried Plantaginis Semen alleviates renal fibrosis by regulating epithelial-mesenchymal transition in renal tubular cells]., PMID:40350903
STAT3-mediated upregulation of TRIM6 promotes hepatocellular carcinoma invasion through the DDX58-Snail1 axis., PMID:40348925
Evaluation of the EMT Markers SNAIL-SLUG and TWIST in Urothelial Carcinoma of the Bladder: A Retrospective Study., PMID:40340993
Store-operated Ca2+ entry is involved in endothelium-to-mesenchymal transition in lung vascular endothelial cells., PMID:40331589
POU6F2 promotes liver metastasis of gastric adenocarcinoma by dual mechanism of transcriptional upregulation of SNAI1 and IGF2/PI3K/AKT signaling-induced conversion of hepatic stellate cells into cancer-associated fibroblasts., PMID:40301686
PYK2 promotes cell proliferation and epithelial-mesenchymal transition in endometriosis by phosphorylating Snail1., PMID:40289074
High Glucose-induced transcriptomic changes in human trabecular meshwork cells., PMID:40278947
Patient-Derived Colorectal Cancer Extracellular Matrices Modulate Cancer Cell Stemness Markers., PMID:40243470
Snail family transcriptional repressor 1 radiosensitizes esophageal cancer via epithelial-mesenchymal transition signaling: From bioinformatics to integrated study., PMID:40235866
VRK1 promotes epithelial-mesenchymal transition in hepatocellular carcinoma mediated by SNAI1 via phosphorylating CHD1L., PMID:40234378
Snail1 as a key prognostic biomarker of cancer-associated fibroblasts in breast tumors., PMID:40222423
Low level of lactate and trophoblast dysfunction mediated by SNAI1/PDK1 contributes to miscarriage., PMID:40187272
MSK1 promotes colorectal cancer metastasis by increasing Snail protein stability through USP5-mediated Snail deubiquitination., PMID:40164688
Identification of a SNAI1 enhancer RNA that drives cancer cell plasticity., PMID:40133308
Cyclic increase in the histamine receptor H1-ADAM9-Snail/Slug axis as a potential therapeutic target for EMT-mediated progression of oral squamous cell carcinoma., PMID:40113769
PFDN1 silencing disrupts critical cancer pathways in triple-negative breast cancer: investigating migration, cell cycle, and apoptosis as a new target therapy., PMID:40063241
E3 ligase HERC5-catalyzed UGDH isgylation promotes SNAI1-mediated tumor metastasis and cisplatin resistance in oral squamous cell carcinoma., PMID:40045362
Single Cell Proteomics Reveals Novel Cell Phenotypes in Marfan Mouse Aneurysm., PMID:40027651
An inherited predisposition allele promotes gastric cancer via enhancing deubiquitination-mediated activation of epithelial-to-mesenchymal transition signaling., PMID:39998882
ZDHHC18 promotes renal fibrosis development by regulating HRAS palmitoylation., PMID:39913299
Inhibition of id-1 reduces osteosarcoma growth and metastasis through mediation of snail., PMID:39891119
Upregulation of the MAP2K4 gene triggers endothelial-mesenchymal transition in COVID-19., PMID:39888478
CCDC154 knockdown inhibits growth of liver cancer via suppressing expression of Snail., PMID:39885494
Programmed cell death protein 5 inhibits hepatocellular carcinoma progression by inducing pyroptosis through regulation of TGF-β/Smad2/3/Snail pathway., PMID:39884472
HDAC3 and Snail2 complex promotes melanoma metastasis by epigenetic repression of IGFBP3., PMID:39864688
A novel piperine derivative HJJ_3_5 inhibits colorectal cancer progression by modulating EMT signaling pathways., PMID:39842333
Mural Cells Initiate Endothelial-to-Mesenchymal Transition in Adjacent Endothelial Cells in Extracranial AVMs., PMID:39768212
High Glucose-Induced Transcriptomic Changes in Human Trabecular Meshwork Cells., PMID:39764143
L3MBTL3 and STAT3 collaboratively upregulate SNAIL expression to promote metastasis in female breast cancer., PMID:39747894
Construction and validation of a senescence-related gene signature for early prediction and treatment of osteoarthritis based on bioinformatics analysis., PMID:39738612
High Shear Stress Reduces ERG Causing Endothelial-Mesenchymal Transition and Pulmonary Arterial Hypertension., PMID:39723537
Multimodal tumor suppression by METTL3 gene knockdown in melanoma and colon cancer cells., PMID:39720980
Loss of SMARCA4 induces sarcomatogenesis through epithelial-mesenchymal transition in ovarian carcinosarcoma., PMID:39716847
ANGPTL3 overcomes sorafenib resistance via suppression of SNAI1 and CPT1A in liver cancer., PMID:39708716
SNAI1 promotes epithelial-mesenchymal transition and maintains cancer stem cell-like properties in thymic epithelial tumors through the PIK3R2/p-EphA2 Axis., PMID:39702326
Characterization of Epithelial-Mesenchymal and Neuroendocrine Differentiation States in Pancreatic and Small Cell Ovarian Tumor Cells and Their Modulation by TGF-β1 and BMP-7., PMID:39682758
Characterization of the Ocular Phenotype in a Col4a3 Knockout Mouse Model of Alport Syndrome., PMID:39680378
DRD4 Interacts with TGF-β Receptors to Drive Colorectal Cancer Metastasis Independently of Dopamine Signaling Pathway., PMID:39679842
Identification of TUBB3 as an immunotherapy target in lung cancer by genome wide in vivo CRISPR screening., PMID:39671912
Influence of Epithelial-Mesenchymal Transition on Risk of Relapse and Outcome to Eribulin or Cyclin-Dependent Kinase Inhibitors in Metastatic Breast Cancer., PMID:39642326
Blocking CXCR3B Expression Increases Tumor Aggressiveness in Hepatocellular Carcinoma., PMID:39626933