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Anti-Human CD3E Antibody (UCHT-1), PE

Catalog #:   FHC27722 Specific References (49) DATASHEET
Host species: Rabbit
Isotype: IgG, kappa
Applications: FCM
Accession: P07766
Overview

Catalog No.

FHC27722

Species reactivity

Human

Host species

Rabbit

Isotype

IgG, kappa

Clonality

Monoclonal

Conjugation

PE

Target

T3E, T-cell surface antigen T3/Leu-4 epsilon chain, CD3e, CD3E, T-cell surface glycoprotein CD3 epsilon chain,UCHT1

Concentration

0.5 mg/ml

Endotoxin level

Please contact with the lab for this information.

Accession

P07766

Applications

FCM

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300.

Stability and Storage

Store at 4°C for 12 months. Protect from light. Do not freeze.

Clone ID

UCHT-1

Data Image
References

Solution structure and synaptic analyses reveal determinants of bispecific T cell engager potency., PMID:40445758

Reactivation of CTLA4-expressing T cells accelerates resolution of lung fibrosis in a humanized mouse model., PMID:40100323

The Novel HDAC Inhibitor OBP-801 Promotes MHC Class I Presentation Through LMP2 Upregulation, Enhancing the PD-1-Targeting Therapy in Clear Cell Renal Cell Carcinoma., PMID:39682244

Nanoparticle containing recombinant excretory/secretory-24 protein of Haemonchus contortus enhanced the cellular immune responses in mice., PMID:39600880

Tanshinone I inhibits the functions of T lymphocytes and exerts therapeutic effects on delayed-type hypersensitivity reaction via blocking STATs signaling pathways., PMID:39536856

From TCR fundamental research to innovative chimeric antigen receptor design., PMID:39433885

Immunogenicity of an Inactivated Senecavirus A Vaccine with a Contemporary Brazilian Strain in Mice., PMID:39203971

Evaluation of non-invasive biomarkers of kidney allograft rejection in a prospective multicenter unselected cohort study (EU-TRAIN)., PMID:39197587

Synthesis and Activity of T-Cell Tumor-Directing MegaMolecules., PMID:39167468

Immune profiling of mouse lung adenocarcinoma paraffin tissues using multiplex immunofluorescence panel: a pilot study., PMID:38877529

Tumor microenvironment restricts IL-10 induced multipotent progenitors to myeloid-lymphatic phenotype., PMID:38640116

ITPRIPL1 binds CD3ε to impede T cell activation and enable tumor immune evasion., PMID:38614099

Dynamics of Whole Transcriptome Analysis (WTA) and Surface markers expression (AbSeq) in Immune Cells of COVID-19 Patients and Recovered captured through Single Cell Genomics., PMID:38357647

Urinary Cell Gene Signature of Acute Rejection in Kidney Allografts., PMID:38196644

Immunization of BALB/c Mice with Killed Tachyzoites of Toxoplasma gondii against Acute Toxoplasmosis., PMID:38169648

Development and characterization of NILK-2301, a novel CEACAM5xCD3 κλ bispecific antibody for immunotherapy of CEACAM5-expressing cancers., PMID:38087365

Exploring urinary extracellular vesicles for organ transplant monitoring: A comprehensive study for detection of allograft dysfunction using immune-specific markers., PMID:37633321

Autoimmune thyroid disease disrupts immune homeostasis in the endometrium of unexplained infertility women-a single-cell RNA transcriptome study during the implantation window., PMID:37501789

Prognostic Impact of the Immunoscore Based on Whole-Slide Image Analysis of CD3+ Tumor-Infiltrating Lymphocytes in Diffuse Large B-Cell Lymphoma., PMID:37257823

An Fc Binding Peptide-Based Facile and Versatile Build Platform for Multispecific Antibodies., PMID:37186944

OMIP-088: Twenty-target imaging mass cytometry panel for major cell populations in mouse formalin fixed paraffin embedded liver., PMID:36602064

In-depth immunophenotyping reveals significant alteration of lymphocytes in buffalo with brucellosis., PMID:36602043

CD3e-immunotoxin spares CD62Llo Tregs and reshapes organ-specific T-cell composition by preferentially depleting CD3ehi T cells., PMID:36389741

Shortened Hinge Design of Fab x sdAb-Fc Bispecific Antibodies Enhances Redirected T-Cell Killing of Tumor Cells., PMID:36291540

Preclinical characterization of a Fab-like CD3/CLDN18.2 XFab® bispecific antibody against solid tumors., PMID:36198215

Comparison of CD3e Antibody and CD3e-sZAP Immunotoxin Treatment in Mice Identifies sZAP as the Main Driver of Vascular Leakage., PMID:35740248

The establishment and application of CD3E humanized mice in immunotherapy., PMID:35570001

Priming treatment with T-cell redirecting bispecific antibody ERY974 reduced cytokine induction without losing cytotoxic activity in vitro by changing the chromatin state in T cells., PMID:35304238

Humanization of a strategic CD3 epitope enables evaluation of clinical T-cell engagers in a fully immunocompetent in vivo model., PMID:35241687

In situ T-cell transfection by anti-CD3-conjugated lipid nanoparticles leads to T-cell activation, migration, and phenotypic shift., PMID:35078042

[Bispecific antibodies targeting CD3 in oncology and hematology]., PMID:34920802

[Bispecific antibodies: An old story with a bright future… with CAR-T cells!]., PMID:34920800

Decreased expression of T-cell-associated immune markers predicts poor prognosis in patients with follicular lymphoma., PMID:34837284

Investigation of neuro-inflammatory parameters in a cuprizone induced mouse model of multiple sclerosis., PMID:34803461

Immune cells in the small intestinal mucosa of newborn yaks., PMID:34642930

Identification of CD8+ T Cell-Related Genes: Correlations with Immune Phenotypes and Outcomes of Liver Cancer., PMID:34124275

Establishment and validation of immune microenvironmental gene signatures for predicting prognosis in patients with head and neck squamous cell carcinoma., PMID:34091115

CAR- and TRuC-redirected regulatory T cells differ in capacity to control adaptive immunity to FVIII., PMID:33940160

Urinary Cell mRNA Profiles Predictive of Human Kidney Allograft Status., PMID:33906907

Construction of a full-length antibody phage display vector., PMID:33838171

Oncolytic herpesvirus expressing PD-L1 BiTE for cancer therapy: exploiting tumor immune suppression as an opportunity for targeted immunotherapy., PMID:33820820

Anti-mucin 1 chimeric antigen receptor T cells for adoptive T cell therapy of cholangiocarcinoma., PMID:33737613

Novel CD3Z and CD3E Deficiency in Two Unrelated Females., PMID:33655388

A humanized CD3ε-knock-in mouse model for pre-clinical testing of anti-human CD3 therapy., PMID:33596227

CD3E as a new predictive biomarker of response to omalizumab treatment in asthma patients: Evidence from bioinformatic analysis., PMID:33578181

Discovery and optimization of a novel anti-GUCY2c x CD3 bispecific antibody for the treatment of solid tumors., PMID:33459147

Molecular and cellular characterization of European sea bass CD3ε+ T lymphocytes and their modulation by microalgal feed supplementation., PMID:33433686

Nanoparticles (PLGA and Chitosan)-Entrapped ADP-Ribosylation Factor 1 of Haemonchus contortus Enhances the Immune Responses in ICR Mice., PMID:33276581

Melanoma cells can be eliminated by sialylated CD43 × CD3 bispecific T cell engager formats in vitro and in vivo., PMID:33225419

Datasheet
$ 156
Product specifications
50 T 156 100 T 258

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For research use only. Not for human or drug use.

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Anti-Human CD3E Antibody (UCHT-1), PE [FHC27722]
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