Catalog No.
DHD85402
Expression system
Mammalian Cells
Species reactivity
Human
Host species
Humanized
Isotype
Fab'-G1-kappa
Clonality
Monoclonal
Target
sCD40L, Tumor necrosis factor ligand superfamily member 5, T-cell antigen Gp39, CD40L, TNFSF5, CD154, CD40-L, TNF-related activation protein, CD40 ligand, CD40LG, TRAP
Concentration
0.82 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P29965
Applications
Research Grade Biosimilar
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternative Names
CDP7657, CAS: 1416147-64-2
Clone ID
Dapirolizumab
Kidney outcomes for children with lupus nephritis, PMID: 32725543
Treatment of cutaneous lupus erythematosus: current approaches and future strategies, PMID: 32141953
Repeated administration of dapirolizumab pegol in a randomised phase I study is well tolerated and accompanied by improvements in several composite measures of systemic lupus erythematosus disease activity and changes in whole blood transcriptomic profiles, PMID: 28780512
Correction: Repeated administration of dapirolizumab pegol in a randomised phase I study is well tolerated and accompanied by improvements in several composite measures of systemic lupus erythematosus disease activity and changes in whole blood transcriptomic profiles, PMID: 29650644
Phase 2, Randomized, Placebo-Controlled Trial of Dapirolizumab Pegol in Patients with Moderate-to-Severe Active Systemic Lupus Erythematosus, PMID: 33956056
Recent developments in biologic therapies for the treatment of patients with systemic lupus erythematosus, PMID: 29660084
Lupus in crisis: as failures pile up, clinicians call for new tools, PMID: 30605161
First-in-human trial of the safety, pharmacokinetics and immunogenicity of a PEGylated anti-CD40L antibody fragment (CDP7657) in healthy individuals and patients with systemic lupus erythematosus, PMID: 25784719
For research use only. Not for human or drug use.
