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Anti-Human NECTIN4/PVRL4 Antibody (Nec4.05), APC

Catalog #:   FHJ41033 Specific References (98) DATASHEET
Host species: Human
Isotype: IgG1, kappa
Applications: ELISA, FCM
Accession: Q96NY8
Overview

Catalog No.

FHJ41033

Species reactivity

Human

Host species

Human

Isotype

IgG1, kappa

Clonality

Monoclonal

Conjugation

APC

Target

LNIR, NECTIN4, PRR4 receptor-related protein 4, Nectin cell adhesion molecule 4, Ig superfamily receptor LNIR, Nectin-4, PVRL4

Concentration

0.5 mg/ml

Endotoxin level

Please contact with the lab for this information.

Accession

Q96NY8

Applications

ELISA, FCM

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300.

Stability and Storage

Store at 4°C for 12 months. Protect from light. Do not freeze.

Clone ID

Nec4.05

Data Image
References

The antibody-drug conjugate sacituzumab govitecan (IMMU-132) represents a potential novel therapeutic strategy in cholangiocarcinoma., PMID:40509933

The antibody-drug conjugate sacituzumab govitecan (IMMU-132) represents a potential novel therapeutic strategy in cholangiocarcinoma., PMID:40509933

Mechanistic Insights into Anti-Nectin4-VcMMAE-Induced Ocular Toxicity: From Cellular Uptake Pathways to Molecular Modification., PMID:40507807

Mechanistic Insights into Anti-Nectin4-VcMMAE-Induced Ocular Toxicity: From Cellular Uptake Pathways to Molecular Modification., PMID:40507807

Enfortumab vedotin induced interstitial lung disease: A first case report with pathological evidence from transbronchial lung cryobiopsy., PMID:40496844

Enfortumab vedotin induced interstitial lung disease: A first case report with pathological evidence from transbronchial lung cryobiopsy., PMID:40496844

Nectin-4-Targeting Radiotracers: Novel Theranostic Agents for Precision Oncology in Cancer., PMID:40474033

Nectin-4-Targeting Radiotracers: Novel Theranostic Agents for Precision Oncology in Cancer., PMID:40474033

Antibody-drug conjugates as game changers in bladder cancer: current progress and future directions., PMID:40433388

Antibody-drug conjugates as game changers in bladder cancer: current progress and future directions., PMID:40433388

Ecology and evolutionary trajectories of morbilliviruses in Neotropical bats., PMID:40425830

Ecology and evolutionary trajectories of morbilliviruses in Neotropical bats., PMID:40425830

E-VIRTUE: a study of enfortumab vedotin with or without pembrolizumab in rare genitourinary tumors-design and rationale., PMID:40421891

E-VIRTUE: a study of enfortumab vedotin with or without pembrolizumab in rare genitourinary tumors-design and rationale., PMID:40421891

Assessment of trophoblast cell-surface antigen 2 (TROP2) and nectin-4 expression in choriocarcinoma., PMID:40414312

Assessment of trophoblast cell-surface antigen 2 (TROP2) and nectin-4 expression in choriocarcinoma., PMID:40414312

Trop2, Nectin-4, and PD-L1 expression profiles in esophageal squamous cell carcinoma: Implications for combined immunotherapy and ADC targeted therapies., PMID:40403357

Trop2, Nectin-4, and PD-L1 expression profiles in esophageal squamous cell carcinoma: Implications for combined immunotherapy and ADC targeted therapies., PMID:40403357

Zelenectide pevedotin (BT-8009): a bicyclic peptide toxin conjugate targeting nectin-4 for the treatment of bladder cancer., PMID:40401457

Zelenectide pevedotin (BT-8009): a bicyclic peptide toxin conjugate targeting nectin-4 for the treatment of bladder cancer., PMID:40401457

NECTIN4 regulates the cell surface expression of CD155 in non-small cell lung cancer cells and induces tumor resistance to PD-1 inhibitors., PMID:40392373

NECTIN4 regulates the cell surface expression of CD155 in non-small cell lung cancer cells and induces tumor resistance to PD-1 inhibitors., PMID:40392373

Research hotspots and frontier analysis of the novel immune checkpoint Nectin-4., PMID:40380880

Research hotspots and frontier analysis of the novel immune checkpoint Nectin-4., PMID:40380880

Immune Checkpoint Inhibitors and Antibody-Drug Conjugates in Urothelial Carcinoma: Current Landscape and Future Directions., PMID:40361519

Immune Checkpoint Inhibitors and Antibody-Drug Conjugates in Urothelial Carcinoma: Current Landscape and Future Directions., PMID:40361519

Biomarkers of response to antibody-drug conjugates (TROP2 and nectin-4) and the immune microenvironment (NKG7, PD-L1, and B7-H3) in penile squamous cell carcinoma., PMID:40327767

Biomarkers of response to antibody-drug conjugates (TROP2 and nectin-4) and the immune microenvironment (NKG7, PD-L1, and B7-H3) in penile squamous cell carcinoma., PMID:40327767

9MW2821, a next-generation Nectin-4 targeting antibody-drug conjugate, in patients with advanced solid tumors: a first-in-human, open label, multicenter, phase Ⅰ/Ⅱ study., PMID:40288679

9MW2821, a next-generation Nectin-4 targeting antibody-drug conjugate, in patients with advanced solid tumors: a first-in-human, open label, multicenter, phase Ⅰ/Ⅱ study., PMID:40288679

Evaluation of Nectin-4 and Trop-2: Implications for Patient Outcomes and Therapy in Penile Cancer., PMID:40252843

Evaluation of Nectin-4 and Trop-2: Implications for Patient Outcomes and Therapy in Penile Cancer., PMID:40252843

Clinical Response to Enfortumab Vedotin and Pembrolizumab in a Patient with Vaginal Squamous Cell Carcinoma: A Case Report., PMID:40235861

Clinical Response to Enfortumab Vedotin and Pembrolizumab in a Patient with Vaginal Squamous Cell Carcinoma: A Case Report., PMID:40235861

Strategies to overcome resistance to enfortumab vedotin and pembrolizumab for patients with urothelial carcinoma: harnessing present knowledge for future advances., PMID:40225697

Strategies to overcome resistance to enfortumab vedotin and pembrolizumab for patients with urothelial carcinoma: harnessing present knowledge for future advances., PMID:40225697

High-glucose-associated YTHDC1 lactylation reduces the sensitivity of bladder cancer to enfortumab vedotin therapy., PMID:40215164

High-glucose-associated YTHDC1 lactylation reduces the sensitivity of bladder cancer to enfortumab vedotin therapy., PMID:40215164

Nectin-4 expression patterns and therapeutics in oncology., PMID:40209851

Nectin-4 expression patterns and therapeutics in oncology., PMID:40209851

Emerging Paradigms in Genitourinary Cancers: Integrating Molecular Imaging, Hypoxia-Inducible Factor-Targeted Therapies, and Antibody-Drug Conjugates in Renal Cell and Urothelial Carcinomas., PMID:40198857

Emerging Paradigms in Genitourinary Cancers: Integrating Molecular Imaging, Hypoxia-Inducible Factor-Targeted Therapies, and Antibody-Drug Conjugates in Renal Cell and Urothelial Carcinomas., PMID:40198857

Potency-optimized CD28-activating bispecific antibody for the targeted treatment of Nectin-4 positive cancers., PMID:40187750

Potency-optimized CD28-activating bispecific antibody for the targeted treatment of Nectin-4 positive cancers., PMID:40187750

A case of remarkable response to combined radiation therapy, enfortumab vedotin, and pembrolizumab in metastatic urothelial carcinoma., PMID:40160871

A case of remarkable response to combined radiation therapy, enfortumab vedotin, and pembrolizumab in metastatic urothelial carcinoma., PMID:40160871

Enfortumab vedotin and pembrolizumab: redefining the standard of care for previously untreated advanced urothelial cancer., PMID:40129250

Enfortumab vedotin and pembrolizumab: redefining the standard of care for previously untreated advanced urothelial cancer., PMID:40129250

Theranostic implications of Nectin-4 oncoprotein in gynecologic cancers: A review., PMID:40101551

Theranostic implications of Nectin-4 oncoprotein in gynecologic cancers: A review., PMID:40101551

Spatial Expression of HER2, NECTIN4, and TROP-2 in Muscle-Invasive Bladder Cancer and Metastases: Implications for Pathological and Clinical Management., PMID:40086591

Spatial Expression of HER2, NECTIN4, and TROP-2 in Muscle-Invasive Bladder Cancer and Metastases: Implications for Pathological and Clinical Management., PMID:40086591

Uncovering potential targets for antibody-drug conjugates in the treatment of gynecologic malignancies., PMID:40046734

Uncovering potential targets for antibody-drug conjugates in the treatment of gynecologic malignancies., PMID:40046734

A novel and promising therapeutic approach for treating pancreatic cancer: Nectin‑4‑targeted antibody‑drug conjugates alone or combined with autophagy inhibitors., PMID:40017149

A novel and promising therapeutic approach for treating pancreatic cancer: Nectin‑4‑targeted antibody‑drug conjugates alone or combined with autophagy inhibitors., PMID:40017149

Understanding the Toxicity Profile of Approved ADCs., PMID:40006625

Understanding the Toxicity Profile of Approved ADCs., PMID:40006625

225Ac/89Zr-Labeled N4MU01 Radioimmunoconjugates as Theranostics Against Nectin-4-Positive Triple-Negative Breast Cancer., PMID:39978811

225Ac/89Zr-Labeled N4MU01 Radioimmunoconjugates as Theranostics Against Nectin-4-Positive Triple-Negative Breast Cancer., PMID:39978811

Nectin-4: A promising prognostic marker and therapeutic target in cancer., PMID:39939077

Nectin-4: A promising prognostic marker and therapeutic target in cancer., PMID:39939077

Durable response to treatment of an atypical desmoplastic small round cell tumor with enfortumab-vedotin., PMID:39928161

Durable response to treatment of an atypical desmoplastic small round cell tumor with enfortumab-vedotin., PMID:39928161

Association of body mass index and tumor response in metastatic urothelial carcinoma treated with enfortumab vedotin: data from the ULTRA-Japan consortium., PMID:39890750

Association of body mass index and tumor response in metastatic urothelial carcinoma treated with enfortumab vedotin: data from the ULTRA-Japan consortium., PMID:39890750

Tissue-Based Biomarkers Important for Prognostication and Management of Genitourinary Tumors, Including Surrogate Markers of Genomic Alterations., PMID:39890303

Tissue-Based Biomarkers Important for Prognostication and Management of Genitourinary Tumors, Including Surrogate Markers of Genomic Alterations., PMID:39890303

Predictive role of ABC transporters in the efficacy of enfortumab vedotin for urothelial carcinoma., PMID:39877564

Predictive role of ABC transporters in the efficacy of enfortumab vedotin for urothelial carcinoma., PMID:39877564

Nuclear Medicine and Molecular Imaging in Urothelial Cancer: Current Status and Future Directions., PMID:39858014

Nuclear Medicine and Molecular Imaging in Urothelial Cancer: Current Status and Future Directions., PMID:39858014

Antibody-drug conjugates in urothelial carcinoma: current status and future., PMID:39844537

Antibody-drug conjugates in urothelial carcinoma: current status and future., PMID:39844537

Spatial distribution and subtype-specific expression patterns of Nectin-4 in muscle-invasive bladder cancer., PMID:39801278

Spatial distribution and subtype-specific expression patterns of Nectin-4 in muscle-invasive bladder cancer., PMID:39801278

Targeted therapies and molecular targets in the therapeutic landscape of advanced urothelial carcinoma: state of the art and future perspectives., PMID:39764422

Targeted therapies and molecular targets in the therapeutic landscape of advanced urothelial carcinoma: state of the art and future perspectives., PMID:39764422

NECTIN-4 PET FOR OPTIMIZING ENFORTUMAB VEDOTIN DOSE-RESPONSE IN UROTHELIAL CARCINOMA., PMID:39763905

NECTIN-4 PET FOR OPTIMIZING ENFORTUMAB VEDOTIN DOSE-RESPONSE IN UROTHELIAL CARCINOMA., PMID:39763905

Exploring novel therapeutic targets in small bowel adenocarcinoma: insights from claudin 18.2, nectin-4, and HER3 expression analysis., PMID:39754977

Nectin-4 Expression in Prostatic Adenocarcinoma: An Immunohistochemical Study., PMID:39748460

Nectin-4 Expression in Prostatic Adenocarcinoma: An Immunohistochemical Study., PMID:39748460

[Pathology and molecular pathology of carcinoma of the penis]., PMID:39694900

Nectin-4 Positivity in Genitourinary Malignancies: A Systematic Review., PMID:39626158

Nectin-4 Positivity in Genitourinary Malignancies: A Systematic Review., PMID:39626158

[Muscle-invasive and metastatic urothelial carcinoma from a pathological point of view]., PMID:39603252

[Muscle-invasive and metastatic urothelial carcinoma from a pathological point of view]., PMID:39603252

Lung Toxicity Occurring During Enfortumab Vedotin Treatment: From a Priming Case Report to a Retrospective Analysis., PMID:39598456

Lung Toxicity Occurring During Enfortumab Vedotin Treatment: From a Priming Case Report to a Retrospective Analysis., PMID:39598456

Assessing the expression of Nectin-4 in solid tumors by immunohistochemistry - what do we know?, PMID:39582282

Assessing the expression of Nectin-4 in solid tumors by immunohistochemistry - what do we know?, PMID:39582282

Targeted therapeutic strategies for Nectin-4 in breast cancer: Recent advances and future prospects., PMID:39577073

Targeted therapeutic strategies for Nectin-4 in breast cancer: Recent advances and future prospects., PMID:39577073

Phase 2 Trial of Enfortumab Vedotin in Patients With Previously Treated Locally Advanced or Metastatic Urothelial Carcinoma in China., PMID:39530574

Phase 2 Trial of Enfortumab Vedotin in Patients With Previously Treated Locally Advanced or Metastatic Urothelial Carcinoma in China., PMID:39530574

Utilizing Patient-Derived Xenografts to Model Precision Oncology for Biliary Tract Cancer., PMID:39513959

Utilizing Patient-Derived Xenografts to Model Precision Oncology for Biliary Tract Cancer., PMID:39513959

Datasheet
$ 258
Product specifications
50 T 258 100 T 426

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Anti-Human NECTIN4/PVRL4 Antibody (Nec4.05), APC [FHJ41033]
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