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Anti-Mouse NOTCH2/3 Antibody (59R1), APC

Catalog #:   FMG01813 Specific References (94) DATASHEET
Host species: Rat
Isotype: IgG1, kappa
Applications: ELISA, FCM
Accession: O35516, Q61982
Overview

Catalog No.

FMG01813

Species reactivity

Human, Mouse

Host species

Rat

Isotype

IgG1, kappa

Clonality

Monoclonal

Conjugation

APC

Target

N2ICD, N2ECD, NOTCH2, hN2, Neurogenic locus notch homolog protein 2, Notch 2, Neurogenic locus notch homolog protein 3, NOTCH3, Notch 3

Concentration

0.5 mg/ml

Endotoxin level

Please contact with the lab for this information.

Accession

O35516, Q61982

Applications

ELISA, FCM

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300.

Stability and Storage

Store at 4°C for 12 months. Protect from light. Do not freeze.

Clone ID

59R1

Data Image
References

Treatment outcomes of BTK inhibitors and venetoclax with or without anti-CD20 monoclonal antibody in relapsed or refractory mantle cell lymphoma., PMID:40278919

Treatment outcomes of BTK inhibitors and venetoclax with or without anti-CD20 monoclonal antibody in relapsed or refractory mantle cell lymphoma., PMID:40278919

Case report: Near-complete response to neratinib-based treatment in HR-positive HER2-amplified metastatic breast cancer refractory to trastuzumab deruxtecan., PMID:39931207

Combined Molecular Subclass and Immune Phenotype Correlate to Atezolizumab Plus Radiation Therapy Response in Invasive Bladder Cancer: BPT-ART Phase 2 Study., PMID:39755215

Combined Molecular Subclass and Immune Phenotype Correlate to Atezolizumab Plus Radiation Therapy Response in Invasive Bladder Cancer: BPT-ART Phase 2 Study., PMID:39755215

TP53 Mutation Is the Only Robust Mutational Biomarker for Outcome Found in a Consecutive Clinical Cohort of Real-Word Patients With Primary Large B-Cell Lymphoma., PMID:39691999

TP53 Mutation Is the Only Robust Mutational Biomarker for Outcome Found in a Consecutive Clinical Cohort of Real-Word Patients With Primary Large B-Cell Lymphoma., PMID:39691999

Truncated recombinant Jagged1 fused with human IgG1 Fc activates Notch target genes in human periodontal ligament cells., PMID:39643955

Truncated recombinant Jagged1 fused with human IgG1 Fc activates Notch target genes in human periodontal ligament cells., PMID:39643955

Modulation of Notch signaling pathway in activated hepatic stellate cells does not ameliorate the outcome of liver fibrosis in carbon tetrachloride and DDC-feeding models., PMID:39529885

Modulation of Notch signaling pathway in activated hepatic stellate cells does not ameliorate the outcome of liver fibrosis in carbon tetrachloride and DDC-feeding models., PMID:39529885

Familial adult-onset neuronal intranuclear inclusion disease: A case report and literature review., PMID:39496005

Familial adult-onset neuronal intranuclear inclusion disease: A case report and literature review., PMID:39496005

Notch1 blockade by a novel, selective anti-Notch1 neutralizing antibody improves immunotherapy efficacy in melanoma by promoting an inflamed TME., PMID:39491031

Notch1 blockade by a novel, selective anti-Notch1 neutralizing antibody improves immunotherapy efficacy in melanoma by promoting an inflamed TME., PMID:39491031

The Marginal Zone B Cell Compartment and T Cell-independent Antibody Responses Are Supported by B Cell Intrinsic Expression of IRF1., PMID:39451043

The Marginal Zone B Cell Compartment and T Cell-independent Antibody Responses Are Supported by B Cell Intrinsic Expression of IRF1., PMID:39451043

Application of Monoclonal Antibodies against Naturally Occurring Bioactive Ingredients., PMID:39189231

Application of Monoclonal Antibodies against Naturally Occurring Bioactive Ingredients., PMID:39189231

Notch2 signaling governs activated B cells to form memory B cells., PMID:38990721

Notch2 signaling governs activated B cells to form memory B cells., PMID:38990721

Disulfide-constrained peptide scaffolds enable a robust peptide-therapeutic discovery platform., PMID:38547109

Disulfide-constrained peptide scaffolds enable a robust peptide-therapeutic discovery platform., PMID:38547109

Notch2 controls developmental fate choices between germinal center and marginal zone B cells upon immunization., PMID:38438375

Notch-1/2 receptors and Jagged-1 ligand, but not HERP-1 transcription factor, are immunohistochemically expressed in the epithelial lining of periapical cysts., PMID:38314334

Notch2 controls developmental fate choices between germinal center and marginal zone B cells upon immunization., PMID:38438375

Chronic Lymphocytic Leukemia IGHV Somatic Hypermutation Detection by Targeted Capture Next-Generation Sequencing., PMID:38175592

NOTCH2 sensitizes the chondrocyte to the inflammatory response of tumor necrosis factor α., PMID:37865314

Chronic Lymphocytic Leukemia IGHV Somatic Hypermutation Detection by Targeted Capture Next-Generation Sequencing., PMID:38175592

Heimdall, an alternative protein issued from a ncRNA related to kappa light chain variable region of immunoglobulins from astrocytes: a new player in neural proteome., PMID:37587118

Heimdall, an alternative protein issued from a ncRNA related to kappa light chain variable region of immunoglobulins from astrocytes: a new player in neural proteome., PMID:37587118

Trastuzumab-induced human cardiomyocyte damage through the Notch2/JAK2/STAT3 pathway., PMID:37567042

Trastuzumab-induced human cardiomyocyte damage through the Notch2/JAK2/STAT3 pathway., PMID:37567042

Genomics of ERBB2-Positive Breast Cancer in Young Women Before and After Exposure to Chemotherapy Plus Trastuzumab., PMID:37364233

Genomics of ERBB2-Positive Breast Cancer in Young Women Before and After Exposure to Chemotherapy Plus Trastuzumab., PMID:37364233

DLBCL-associated NOTCH2 mutations escape ubiquitin-dependent degradation and promote chemoresistance., PMID:37235754

DLBCL-associated NOTCH2 mutations escape ubiquitin-dependent degradation and promote chemoresistance., PMID:37235754

Overexpression and potential roles of midkine via regulation of vascular endothelial growth factor A in psoriasis., PMID:37218430

Overexpression and potential roles of midkine via regulation of vascular endothelial growth factor A in psoriasis., PMID:37218430

Clinical, radiological, and molecular analyses of neuronal intranuclear inclusion disease with polyglycine inclusions., PMID:37001413

Clinical, radiological, and molecular analyses of neuronal intranuclear inclusion disease with polyglycine inclusions., PMID:37001413

Waldenström Macroglobulinemia and Non-IgM-Type Lymphoplasmacytic Lymphoma Are Genetically Similar., PMID:36917966

Waldenström Macroglobulinemia and Non-IgM-Type Lymphoplasmacytic Lymphoma Are Genetically Similar., PMID:36917966

CK2β-regulated signaling controls B cell differentiation and function., PMID:36713383

CK2β-regulated signaling controls B cell differentiation and function., PMID:36713383

Role of Notch2 pathway in mature B cell malignancies., PMID:36686759

Role of Notch2 pathway in mature B cell malignancies., PMID:36686759

Exploratory use of romosozumab for osteoporosis in a patient with Hajdu-Cheney syndrome: a case report., PMID:36622389

Exploratory use of romosozumab for osteoporosis in a patient with Hajdu-Cheney syndrome: a case report., PMID:36622389

Notch2-dependent GATA3+ Treg cells alleviate allergic rhinitis by suppressing the Th2 cell response., PMID:36155282

Notch2-dependent GATA3+ Treg cells alleviate allergic rhinitis by suppressing the Th2 cell response., PMID:36155282

Notch Signaling Promotes Mature T-Cell Lymphomagenesis., PMID:36006995

Notch Signaling Promotes Mature T-Cell Lymphomagenesis., PMID:36006995

Therapeutic Targeting Notch2 Protects Bone Micro-Vasculatures from Methotrexate Chemotherapy-Induced Adverse Effects in Rats., PMID:35954226

Therapeutic Targeting Notch2 Protects Bone Micro-Vasculatures from Methotrexate Chemotherapy-Induced Adverse Effects in Rats., PMID:35954226

Extra arginine supplementation during the suckling period alleviates weaning stress through the regulation of dendritic cells and Notch2 signaling in piglets., PMID:35899814

Extra arginine supplementation during the suckling period alleviates weaning stress through the regulation of dendritic cells and Notch2 signaling in piglets., PMID:35899814

FcγRIIB regulates autoantibody responses by limiting marginal zone B cell activation., PMID:35819855

FcγRIIB regulates autoantibody responses by limiting marginal zone B cell activation., PMID:35819855

Iristectorigenin A exerts novel protective properties against airway inflammation and mucus hypersecretion in OVA-induced asthmatic mice: Iristectorigenin A ameliorates asthma phenotype., PMID:35752075

Iristectorigenin A exerts novel protective properties against airway inflammation and mucus hypersecretion in OVA-induced asthmatic mice: Iristectorigenin A ameliorates asthma phenotype., PMID:35752075

Pancreatic-Like Cells Derived From Mouse Embryonic Stem Cells Are Regulated by Pdx1 Involving the Notch Pathway., PMID:35695761

Pancreatic-Like Cells Derived From Mouse Embryonic Stem Cells Are Regulated by Pdx1 Involving the Notch Pathway., PMID:35695761

Stromal Notch ligands foster lymphopenia-driven functional plasticity and homeostatic proliferation of naive B cells., PMID:35579963

Stromal Notch ligands foster lymphopenia-driven functional plasticity and homeostatic proliferation of naive B cells., PMID:35579963

Notch2 Blockade Mitigates Methotrexate Chemotherapy-Induced Bone Loss and Marrow Adiposity., PMID:35563828

Notch2 Blockade Mitigates Methotrexate Chemotherapy-Induced Bone Loss and Marrow Adiposity., PMID:35563828

Methotrexate treatment suppresses osteoblastic differentiation by inducing Notch2 signaling and blockade of Notch2 rescues osteogenesis by preserving Wnt/β-catenin signaling., PMID:34935186

Methotrexate treatment suppresses osteoblastic differentiation by inducing Notch2 signaling and blockade of Notch2 rescues osteogenesis by preserving Wnt/β-catenin signaling., PMID:34935186

Revised International Prognostic Index and genetic alterations are associated with early failure to R-CHOP in patients with diffuse large B-cell lymphoma., PMID:34632572

Revised International Prognostic Index and genetic alterations are associated with early failure to R-CHOP in patients with diffuse large B-cell lymphoma., PMID:34632572

Oral Surgery Procedures in a Patient with Hajdu-Cheney Syndrome Treated with Denosumab-A Rare Case Report., PMID:34501688

Oral Surgery Procedures in a Patient with Hajdu-Cheney Syndrome Treated with Denosumab-A Rare Case Report., PMID:34501688

Cooperation Between Cancer and Fibroblasts in Vascular Mimicry and N2-Type Neutrophil Recruitment via Notch2-Jagged1 Interaction in Lung Cancer., PMID:34485133

Cooperation Between Cancer and Fibroblasts in Vascular Mimicry and N2-Type Neutrophil Recruitment via Notch2-Jagged1 Interaction in Lung Cancer., PMID:34485133

Resting innate-like B cells leverage sustained Notch2/mTORC1 signaling to achieve rapid and mitosis-independent plasma cell differentiation., PMID:34473651

Resting innate-like B cells leverage sustained Notch2/mTORC1 signaling to achieve rapid and mitosis-independent plasma cell differentiation., PMID:34473651

Delta-like 1-Expressing Cells at the Gland Base Promote Proliferation of Gastric Antral Stem Cells in Mouse., PMID:34438113

Delta-like 1-Expressing Cells at the Gland Base Promote Proliferation of Gastric Antral Stem Cells in Mouse., PMID:34438113

Risk-tailored treatment of splenic marginal zone lymphoma., PMID:34407041

Risk-tailored treatment of splenic marginal zone lymphoma., PMID:34407041

Protein Kinase CK2 Regulates B Cell Development and Differentiation., PMID:34301844

Protein Kinase CK2 Regulates B Cell Development and Differentiation., PMID:34301844

Profiling of 520 Candidate Genes in 50 Surgically Treated Chinese Small Cell Lung Cancer Patients., PMID:34168983

Profiling of 520 Candidate Genes in 50 Surgically Treated Chinese Small Cell Lung Cancer Patients., PMID:34168983

A Homozygous Dab1-/- Is a Potential Novel Cause of Autosomal Recessive Congenital Anomalies of the Mice Kidney and Urinary Tract., PMID:33924028

Adult-onset neuronal intranuclear inclusion disease, with both stroke-like onset and encephalitic attacks: a case report., PMID:33789591

Early Covert Appearance of Marginal Zone B Cells in Salivary Glands of Sjögren's Syndrome-Susceptible Mice: Initiators of Subsequent Overt Clinical Disease., PMID:33671965

BAFF promotes heightened BCR responsiveness and manifestations of chronic GVHD after allogeneic stem cell transplantation., PMID:33534893

BAFF promotes heightened BCR responsiveness and manifestations of chronic GVHD after allogeneic stem cell transplantation., PMID:33534893

High expression of Notch2 drives tongue squamous cell carcinoma carcinogenesis., PMID:33382997

High expression of Notch2 drives tongue squamous cell carcinoma carcinogenesis., PMID:33382997

O-Fucose and Fringe-modified NOTCH1 extracellular domain fragments as decoys to release niche-lodged hematopoietic progenitor cells., PMID:33351914

O-Fucose and Fringe-modified NOTCH1 extracellular domain fragments as decoys to release niche-lodged hematopoietic progenitor cells., PMID:33351914

Datasheet
$ 292
Product specifications
50 T 292 100 T 484

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Anti-Mouse NOTCH2/3 Antibody (59R1), APC [FMG01813]
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