Catalog No.
YHA11501
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Arg516
Predicted molecular weight
60.13 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O00429
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Dynamin family member proline-rich carboxyl-terminal domain less, DVLP, Dynamin-like protein IV, Dynamin-related protein 1, Dynamin-like protein, DLP1, Dymple, Dynamin-1-like protein, HdynIV, Dnm1p/Vps1p-like protein, DRP1, DNM1L, Dynamin-like protein 4
Drp1-Mediated Mitochondrial Fission Is Essential for Chemical-Induced Neuronal Transdifferentiation from Human Primary Fibroblasts., PMID:40512396
In-vivo dendrite injury drives local mitochondrial contraction and dendrite branching., PMID:40502170
Shizhifang alleviates hyperuricemia -induced renal injury by inhibiting Drp1 and maintaining mitochondrial homeostasis in renal tubular epithelial cells., PMID:40499801
ER-mitochondria tethering and its signaling: A novel therapeutic target in breast cancer., PMID:40496927
Roles of Mitochondrial Fusion and Division in Harmine Derivative H-2-168-Induced Neurotoxicity., PMID:40496271
Umbelliferone attenuates diabetic sarcopenia by modulating mitochondrial quality and the ubiquitin-proteasome system., PMID:40483791
Coordination of SLC39A1 and DRP1 facilitates HCC recurrence by impairing mitochondrial quality control., PMID:40462487
[Mechanism of vanillic acid against cardiac fibrosis induced by isoproterenol in mice based on Drp1/HK1/NLRP3 and mitochondrial apoptosis signaling pathways]., PMID:40461229
[Study on mechanism of naringin in alleviating cerebral ischemia/reperfusion injury based on DRP1/LRRK2/MCU axis]., PMID:40461204
Cadmium targeting MLKL-Drp1 axis to trigger mitochondrial oxidative stress contributes to necroinflammation in rat kidney., PMID:40460938
Chrysin Mitigates Chromium-Induced Nephrotoxicity Via Modulation of AMPK/SIRT1/NF-κB/p53 Signaling Cascade and PGC-1α Signaling., PMID:40457156
Three-dimensional super-resolution imaging of whole cells using a high numerical aperture oblique-plane microscope., PMID:40445643
SLC-25A46 regulates mitochondrial fusion through FZO-1/Mitofusin and is., PMID:40444356
Endosomal RFFL ubiquitin ligase regulates mitochondrial morphology by targeting Mitofusin 2., PMID:40444323
Hyperbaric oxygen therapy attenuates carbon monoxide-induced lung injury by restoring mitochondrial dynamics and suppressing Pink1/Parkin-mediated mitophagy., PMID:40441279
Unleashing the cardioprotective potential of berberine against doxorubicin cardiotoxicity: Innovative exploitation of the peculiar antipyroptotic/antioxidant/anti-inflammatory capacity via modulation of inflammasome/caspase-1/interleukin pathway in rats., PMID:40440959
Imbalanced mitochondrial dynamics in human PD and α-synuclein mouse brains., PMID:40436283
Mito-TEMPO Mitigates Fibromyalgia Induced by Reserpine in Rats: Orchestration Between SIRT1, Mitochondrial Dynamics, Endoplasmic Reticulum and miRNA-320., PMID:40434586
Soluble Epoxide Hydrolase Inhibition Improves Alzheimer's Disease Hallmarks: Correlation with Peripheral Inflammation and Gut Microbiota Modulation., PMID:40423637
Membrane ATPases and Mitochondrial Proteins in Fetal Cerebellum After Exposure to L-Glutamate During Gestation., PMID:40422762
Impact of Drp1 Loss on Organelle Interaction, Metabolism, and Inflammation in Mouse Liver., PMID:40422182
Disruption of cTnT-Mediated Sarcomere-Mitochondrial Communication Results in Dilated Cardiomyopathy., PMID:40421531
Review of FUNDC1-mediated mitochondrial autophagy in Alzheimer's disease., PMID:40421101
Insertion of mNeonGreen into the variable domain of DRP-1 permits visualization of functional endogenous protein., PMID:40415901
Endoplasmic reticulum tubule junctions are sites of autophagy., PMID:40415242
Isoliquiritigenin attenuated cognitive impairment, cerebral tau phosphorylation and oxidative stress in a streptozotocin-induced mouse model of Alzheimer's disease., PMID:40414556
Nur77 inhibits mitochondrial excessive fragmentation through mutated p53 L194F in T47D breast cancer cells., PMID:40414511
Dehydrodiisoeugenol alleviates palmitate-induced mitochondrial dysfunction in human vascular smooth muscle cells through the activation of SIRT1-mediated Drp1 deacetylation., PMID:40413480
Nucleolin alleviates endotoxemia-induced myocardial dysfunction via inhibiting Drp1-mediated mitochondrial fission., PMID:40412108
Cannabinol (CBN) alleviates age-related cognitive decline by improving synaptic and mitochondrial health., PMID:40412024
Downhill running induced mitophagy in rat soleus muscle via the AMPK pathway., PMID:40411707
Chronic mild stress disrupts mitophagy and mitochondrial status in rat frontal cortex., PMID:40410878
Kaposi's sarcoma-associated herpesvirus induces mitochondrial fission to evade host immune responses and promote viral production., PMID:40404827
Gnetin C sensitizes darolutamide-resistant prostate cancer cells by targeting NAD+ and energy metabolism., PMID:40393106
Copper-Induced DRP1 Activation Disrupts Mitochondrial-Lipid Droplet Contact to Promote Hepatic Steatosis., PMID:40387024
Olaparib Triggers Mitochondrial Fission Through the CDK5/Drp-1 Signaling Pathway in Ovarian Cancer Cells., PMID:40384022
Cold storage effects on mitochondrial bioenergetics and protein expression in human mesenchymal stromal cells., PMID:40380957
MTFR2-Mediated Fission Drives Fatty Acid and Mitochondrial Co-Transfer from Hepatic Stellate Cells to Tumor Cells Fueling Oncogenesis., PMID:40365837
Snapshots of mitochondrial fission imaged by cryo-scanning transmission electron tomography., PMID:40365741
Aquaporin 9: Exacerbation of Vulnerable Carotid Plaque Formation., PMID:40360449
Irisin attenuates cardiac injury and improves prognosis in rats with hemorrhagic shock by maintaining mitochondrial homeostasis via the AMPK/Drp1 pathway., PMID:40356981
Chronic stress elicits sex-specific mitochondrial respiratory functional changes in the rat heart., PMID:40356314
The active metabolite of Epimedii Folium promotes hippocampal neurogenesis in APP/PS1 mice by alleviating mitochondrial dysfunction., PMID:40351431
[Verification of resveratrol ameliorating vascular endothelial damage in sepsis-associated encephalopathy through HIF-1α pathway based on network pharmacology and experiment]., PMID:40350824
Parkin mediates the mitochondrial dysfunction through mRpL18., PMID:40345588
SETDB1 decline promotes the resistance to sorafenib via DRP1 phosphorylation-mediated mitochondrial dysfunction in HepG2 cells., PMID:40345011
A hidden cysteine in Fis1 targeted to prevent excessive mitochondrial fission and dysfunction under oxidative stress., PMID:40328741
Foxp3 confers long-term efficacy of chimeric antigen receptor-T cells via metabolic reprogramming., PMID:40328248
Metformin restores mitochondrial bioenergetics and redox homeostasis through modulation of mitochondrial biogenesis and dynamics in patient derived cultured fibroblasts and an animal model of molybdenum cofactor deficiency., PMID:40327990
Mechanistic study of modulating mitochondrial fission and fusion to ameliorate neuropathic pain in mice., PMID:40320455
For research use only. Not for human or drug use.
