Catalog No.
YHA05601
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met2-Trp317
Predicted molecular weight
37.99 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O00214
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
PCTA-1, Po66 carbohydrate-binding protein, Po66-CBP, Galectin-8, Gal-8, LGALS8, Prostate carcinoma tumor antigen 1
CD98hc, a novel of galectin-8 receptor, binds to galectin-8 in an N-glycosylation-dependent manner., PMID:40205944
Selective autophagy impedes KSHV entry after recruiting the membrane damage sensor galectin-8 to virus-containing endosomes., PMID:39602307
Galectin-8 Contributes to Human Trophoblast Cell Invasion., PMID:39337581
B4GALT1-dependent galectin-8 binding with TGF-β receptor suppresses colorectal cancer progression and metastasis., PMID:39231945
Engineered intrinsically fluorescent galectin-8 variants with altered valency, ligand recognition and biological activity., PMID:39094876
Expression of Intracellular Galectin-8 and -9 in Endometrial Cancer., PMID:39000016
The diverse dependence of galectin-1 and -8 on multivalency for the modulation of FGFR1 endocytosis., PMID:38750548
Galectin-8 inhibition and functions in immune response and tumor biology., PMID:38613488
Breaking barriers: How modified citrus pectin inhibits galectin-8., PMID:38597504
Galectin-8 modulates human osteoclast activity partly through isoform-specific interactions., PMID:38395460
Association of GAL-8 promoter methylation levels with coronary plaque inflammation., PMID:38246423
Hypoxia-induced galectin-8 maintains stemness in glioma stem cells via autophagy regulation., PMID:38158714
Screening and Identifying Reference Genes for Erythrocyte Production from Cord Blood CD34+ Cells Exposed to Hypoxia., PMID:38011643
Long noncoding RNA LGALS8-AS1 promotes angiogenesis and brain metastases in non-small cell lung cancer., PMID:37716002
Long non-coding RNA LGALS8-AS1 facilitates PLAGL2-mediated malignant phenotypes in gastric cancer., PMID:36807469
Membrane Atg8ylation, stress granule formation, and MTOR regulation during lysosomal damage., PMID:36394332
Coronary artery plaque rupture and erosion: Role of wall shear stress profiling and biological patterns in acute coronary syndromes., PMID:36343795
Assessment of galectins -1, -3, -4, -8, and -9 expression in ovarian carcinoma patients with clinical implications., PMID:36050693
Quantitative Proteomics Explore the Potential Targets and Action Mechanisms of Hydroxychloroquine., PMID:36014414
Galectin-8 and -9 as prognostic factors for cervical cancer., PMID:35377045
Galectin-8, cytokines, and the storm., PMID:35015084
A Neoglycoprotein-Immobilized Fluorescent Magnetic Bead Suspension Multiplex Array for Galectin-Binding Studies., PMID:34684775
Selective Monovalent Galectin-8 Ligands Based on 3-Lactoylgalactoside., PMID:34613662
Galectin-8 Senses Phagosomal Damage and Recruits Selective Autophagy Adapter TAX1BP1 To Control Mycobacterium tuberculosis Infection in Macrophages., PMID:34225486
Benzimidazole-galactosides bind selectively to the Galectin-8 N-Terminal domain: Structure-based design and optimisation., PMID:34225180
Cigarette smoke-induced impairment of autophagy in macrophages increases galectin-8 and inflammation., PMID:33432024
Rational Design and Synthesis of Methyl-β-d-galactomalonyl Phenyl Esters as Potent Galectin-8N Antagonists., PMID:32809817
Galectin-8 Is Upregulated in Keratinocytes by IL-17A and Promotes Proliferation by Regulating Mitosis in Psoriasis., PMID:32805218
Transbilayer Movement of Sphingomyelin Precedes Catastrophic Breakage of Enterobacteria-Containing Vacuoles., PMID:32649908
Full-length galectin-8 and separate carbohydrate recognition domains: the whole is greater than the sum of its parts?, PMID:32597487
Galectin-8 Favors VEGF-Induced Angiogenesis: In Vitro Study in Human Umbilical Vein Endothelial Cells and In Vivo Study in Chick Chorioallantoic Membrane., PMID:32487613
A MicroRNA Network Controls Legionella pneumophila Replication in Human Macrophages via LGALS8 and MX1., PMID:32209695
Endophilin-A3 and Galectin-8 control the clathrin-independent endocytosis of CD166., PMID:32193381
A risk signature with four autophagy-related genes for predicting survival of glioblastoma multiforme., PMID:32065482
The role of galectins in virus infection - A systemic literature review., PMID:31630962
Galectin-8 in the onset of the immune response and inflammation., PMID:31529033
GALECTIN-8 Is a Neuroprotective Factor in the Brain that Can Be Neutralized by Human Autoantibodies., PMID:31119556
Dual knockdown of Galectin-8 and its glycosylated ligand, the activated leukocyte cell adhesion molecule (ALCAM/CD166), synergistically delays in vivo breast cancer growth., PMID:30905597
Gal8 Visualization of Endosome Disruption Predicts Carrier-Mediated Biologic Drug Intracellular Bioavailability., PMID:30629431
Galectin-8 induces endothelial hyperpermeability through the eNOS pathway involving S-nitrosylation-mediated adherens junction disassembly., PMID:30624618
Helicobacter pylori induces intracellular galectin-8 aggregation around damaged lysosomes within gastric epithelial cells in a host O-glycan-dependent manner., PMID:30289459
Clinical characteristics and prognostic significance of galectins for patients with gastric cancer: A meta-analysis., PMID:29940258
Galectin-8 induces functional disease markers in human osteoarthritis and cooperates with galectins-1 and -3., PMID:29934665
Structure-Based Design of a Monosaccharide Ligand Targeting Galectin-8., PMID:29926535
Galectins Control mTOR in Response to Endomembrane Damage., PMID:29625033
Overall Survival of Ovarian Cancer Patients Is Determined by Expression of Galectins-8 and -9., PMID:29361803
Galectin-8-mediated selective autophagy protects against seeded tau aggregation., PMID:29282296
Tissue and plasma levels of galectins in patients with high grade serous ovarian carcinoma as new predictive biomarkers., PMID:29038585
Lactose Binding Induces Opposing Dynamics Changes in Human Galectins Revealed by NMR-Based Hydrogen-Deuterium Exchange., PMID:28813004
Galectin-3 Inhibits Galectin-8/Parkin-Mediated Ubiquitination of Group A Streptococcus., PMID:28743815
For research use only. Not for human or drug use.
