Catalog No.
EVV24305
Expression system
Mammalian cells
Species
Lake Victoria marburgvirus (strain Ravn-87) (MARV) (Marburg virus (strain Kenya/Ravn/1987))
Protein length
Val33-Thr425
Predicted molecular weight
71.21 kDa
Nature
Recombinant
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q1PDC7
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Envelope glycoprotein, GP1,2, GP, Virion spike glycoprotein, GP1
Note
For research use only.
Comparison of the protective efficacy of DNA and baculovirus-derived protein vaccines for EBOLA virus in guinea pigs., PMID:12686428
Ebola virus glycoprotein 1: identification of residues important for binding and postbinding events., PMID:17475648
Distinct patterns of IFITM-mediated restriction of filoviruses, SARS coronavirus, and influenza A virus., PMID:21253575
Marburg virus glycoprotein GP2: pH-dependent stability of the ectodomain α-helical bundle., PMID:22369502
Filovirus entry: a novelty in the viral fusion world., PMID:22470835
Crystal structure of the Marburg virus GP2 core domain in its postfusion conformation., PMID:22935026
Cross-protection conferred by filovirus virus-like particles containing trimeric hybrid glycoprotein., PMID:25514232
Role of EXT1 and Glycosaminoglycans in the Early Stage of Filovirus Entry., PMID:25741008
Macaque Monoclonal Antibodies Targeting Novel Conserved Epitopes within Filovirus Glycoprotein., PMID:26468532
Toremifene interacts with and destabilizes the Ebola virus glycoprotein., PMID:27362232
Identity and validity of conserved B cell epitopes of filovirus glycoprotein: towards rapid diagnostic testing for Ebola and possibly Marburg virus disease., PMID:30285648
Longitudinal proteome-wide antibody profiling in Marburg virus survivors identifies wing domain immunogen for vaccine design., PMID:39285186