Catalog No.
YXX23401
Expression system
E. coli
Species
Neisseria meningitidis
Protein length
Ala36-Ser168
Predicted molecular weight
16.34 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
WP_014573675.1
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Major pilin PilE, pilE
Sweet complexity: O-linked protein glycosylation in pathogenic Neisseria., PMID:38808060
Genetic variants linked to the phenotypic outcome of invasive disease and carriage of Neisseria meningitidis., PMID:37874326
Comparison of invasive and non-invasive isolates of Neisseria meningitidis by whole genome sequencing, Czech Republic, 2005-2021., PMID:37344221
Pilus PilA of the naturally competent HACEK group pathogen Aggregatibacter actinomycetemcomitans stimulates human leukocytes and interacts with both DNA and proinflammatory cytokines., PMID:36374775
Sculpting the Bacterial O-Glycoproteome: Functional Analyses of Orthologous Oligosaccharyltransferases with Diverse Targeting Specificities., PMID:35471082
The minor pilin PilV provides a conserved adhesion site throughout the antigenically variable meningococcal type IV pilus., PMID:34725157
Transmission Dynamics and Microevolution of Neisseria meningitidis During Carriage and Invasive Disease in High School Students in Georgia and Maryland, 2006-2007., PMID:33107578
Genetic incorporation of non-canonical amino acid photocrosslinkers in Neisseria meningitidis: New method provides insights into the physiological function of the function-unknown NMB1345 protein., PMID:32866169
Synthesis of orthogonally protected and functionalized bacillosamines., PMID:32236232
Deep mutational scanning of the Neisseria meningitidis major pilin reveals the importance of pilus tip-mediated adhesion., PMID:31609039
Contribution of σ70 and σN Factors to Expression of Class II pilE in Neisseria meningitidis., PMID:31331980
Analysis of Pilin Antigenic Variation in Neisseria meningitidis by Next-Generation Sequencing., PMID:30181126
Whole genome sequencing reveals within-host genetic changes in paired meningococcal carriage isolates from Ethiopia., PMID:28545446
Structural and genetic analyses of glycan O-acetylation in a bacterial protein glycosylation system: evidence for differential effects on glycan chain length., PMID:28460017
Comparative proteomic analysis of Neisseria meningitidis wildtype and dprA null mutant strains links DNA processing to pilus biogenesis., PMID:28431522
Structure of the Neisseria meningitidis Type IV pilus., PMID:27698424
Neisseria meningitidis Polynucleotide Phosphorylase Affects Aggregation, Adhesion, and Virulence., PMID:26930706
The phosphocarrier protein HPr of Neisseria meningitidis interacts with the transcription regulator CrgA and its deletion affects capsule production, cell adhesion, and virulence., PMID:26858137
Neisseria cinerea isolates can adhere to human epithelial cells by type IV pilus-independent mechanisms., PMID:26813911
Characterization of a Unique Tetrasaccharide and Distinct Glycoproteome in the O-Linked Protein Glycosylation System of Neisseria elongata subsp. glycolytica., PMID:26483525
Structural and functional studies of the Pseudomonas aeruginosa minor pilin, PilE., PMID:26359492
Characterization of motility and piliation in pathogenic Neisseria., PMID:25925502
Characterization of a novel antisense RNA in the major pilin locus of Neisseria meningitidis influencing antigenic variation., PMID:25755192
Deciphering the complex three-way interaction between the non-integrin laminin receptor, galectin-3 and Neisseria meningitidis., PMID:25274119
Pathogenic Neisseria meningitidis utilizes CD147 for vascular colonization., PMID:24880614
Sequence, distribution and chromosomal context of class I and class II pilin genes of Neisseria meningitidis identified in whole genome sequences., PMID:24690385
The hypervariable region of meningococcal major pilin PilE controls the host cell response via antigenic variation., PMID:24520062
The use of high-throughput DNA sequencing in the investigation of antigenic variation: application to Neisseria species., PMID:24466206
Complete posttranslational modification mapping of pathogenic Neisseria meningitidis pilins requires top-down mass spectrometry., PMID:24459079
Control of pili and sialyltransferase expression in Neisseria gonorrhoeae is mediated by the transcriptional regulator CrgA., PMID:24433334
Ght protein of Neisseria meningitidis is involved in the regulation of lipopolysaccharide biosynthesis., PMID:24296673
A combined mass spectrometry strategy for complete posttranslational modification mapping of Neisseria meningitidis major pilin., PMID:24259208
Pro-inflammatory cytokines can act as intracellular modulators of commensal bacterial virulence., PMID:24107297
Sigma factor RpoN (σ54) regulates pilE transcription in commensal Neisseria elongata., PMID:23899162
Prevalence and genetic diversity of two adhesion-related genes, pilE and nadA, in Neisseria meningitidis in China., PMID:23290624
Opc expression, LPS immunotype switch and pilin conversion contribute to serum resistance of unencapsulated meningococci., PMID:23028802
Meningococcal PilV potentiates Neisseria meningitidis type IV pilus-mediated internalization into human endothelial and epithelial cells., PMID:22988016
The meningococcal minor pilin PilX is responsible for type IV pilus conformational changes associated with signaling to endothelial cells., PMID:22778100
Large-scale study of the interactions between proteins involved in type IV pilus biology in Neisseria meningitidis: characterization of a subcomplex involved in pilus assembly., PMID:22486968
Neisserial Correia repeat-enclosed elements do not influence the transcription of pil genes in Neisseria gonorrhoeae and Neisseria meningitidis., PMID:21856854
Testing the vaccine potential of PilV, PilX and ComP, minor subunits of Neisseria meningitidis type IV pili., PMID:21803096
Structural characterization of outer membrane components of the type IV pili system in pathogenic Neisseria., PMID:21304951
Sequence conservation of pilus subunits in Neisseria meningitidis., PMID:20457291
Molecular characterization and identification of proteins regulated by Hfq in Neisseria meningitidis., PMID:19374669
Genetic and functional analyses of PptA, a phospho-form transferase targeting type IV pili in Neisseria gonorrhoeae., PMID:17951381
Alternative Neisseria spp. type IV pilin glycosylation with a glyceramido acetamido trideoxyhexose residue., PMID:17804791
Neisseria gonorrhoeae O-linked pilin glycosylation: functional analyses define both the biosynthetic pathway and glycan structure., PMID:17608667
Meningococcal biofilm formation: structure, development and phenotypes in a standardized continuous flow system., PMID:17121595
Analysis of the Piv recombinase-related gene family of Neisseria gonorrhoeae., PMID:15687191
Unique modifications with phosphocholine and phosphoethanolamine define alternate antigenic forms of Neisseria gonorrhoeae type IV pili., PMID:15249686
For research use only. Not for human or drug use.
