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Recombinant Streptococcus pyogenes M protein Protein, N-His

Catalog #:   YXX21703 Specific References (50) DATASHEET
Applications: ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Expression system: E. coli
Accession: Q6RI58
Protein length: [Ala1-Ala50] & [Ala1-Ala50]
Overview

Catalog No.

YXX21703

Expression system

E. coli

Species

Streptococcus pyogenes

Protein length

[Ala1-Ala50] & [Ala1-Ala50]

Predicted molecular weight

14.48 kDa

Nature

Recombinant

Endotoxin level

Please contact with the lab for this information.

Purity

>90% as determined by SDS-PAGE.

Accession

Q6RI58

Applications

ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress

Form

Lyophilized

Storage buffer

Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.

Reconstitution

Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.

Shipping

In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Alternative Names

M protein

Data Image
References

Prevalence and emm typing of multi-drug resistant Streptococcus pyogenes in tertiary care health settings., PMID:40500764

Household molecular epidemiology of Streptococcus pyogenes carriage and infection in The Gambia., PMID:40378280

[Genomic characterization of group A Streptococcus of different emm-type in Tianjin City from 2011 to 2024]., PMID:40374361

Epidemiological and genomic characterisation of an outbreak of Streptococcus pyogenes emm5.23., PMID:40319945

Group A Streptococcus vaccine Development: An Indian public health imperative., PMID:40252837

Additional biomarkers and emm types associated with group A streptococcal toxic shock syndrome: a Japanese nationwide observational study., PMID:40193020

Post-pandemic upsurge in Group A Streptococcus infections at an Italian tertiary university hospital., PMID:40135916

Fibrinogen-binding M-related proteins facilitate the recruitment of plasminogen by Streptococcus pyogenes., PMID:40100134

Structure-Based Development of a Covalent Inhibitor Targeting Streptococcus Pyogenes over Staphylococcus Aureus Sortase A., PMID:40072260

Toxic Shock Syndrome Caused by Streptococcus dysgalactiae Subspecies equisimilis: A Report of a Rare Pediatric Case., PMID:40062160

Streptococcus pyogenes Activates Human Platelets via Streptolysin S-Mediated Calcium Ion Influx., PMID:40031874

Characteristics of Streptococcus pyogenes causing invasive infections among adults in Portugal, 2016-2019: Pre-COVID-19 expansion of the M1UK sublineage., PMID:40021403

Low-dose interleukin 2 therapy halts the progression of post-streptococcal autoimmune complications in a rat model of rheumatic heart disease., PMID:39998162

Streptococcus pyogenes emm Type 3.93 Emergence, the Netherlands and England., PMID:39983683

Unveiling the Group A Streptococcus Vaccine-Based L-Rhamnose from Backbone of Group A Carbohydrate: Current Insight Against Acute Rheumatic Fever to Reduce the Global Burden of Rheumatic Heart Disease., PMID:39959434

Streptococcus pyogenes bloodstream infections in an Italian hospital: A ten-year genomic picture., PMID:39955886

Influence of component structural arrangement on cholesterol-antigen conjugate immunogenicity and antisera bactericidal activity against group A Streptococcus., PMID:39952060

Studying the Oncolytic Activity of Streptococcus pyogenes Strains Against Hepatoma, Glioma, and Pancreatic Cancer In Vitro and In Vivo., PMID:39858844

Group a Streptococcus remains viable inside fibrin clots and gains access to human plasminogen for subsequent fibrinolysis and dissemination., PMID:39804237

Genomic epidemiology of invasive Group A Streptococcus infections in Argentina, 2023: high prevalence of emm1-global and detection of emm1 hypervirulent lineages., PMID:39611833

A phase 1 randomized controlled trial of a peptide-based group A streptococcal vaccine in healthy volunteers., PMID:39563457

Clinical and microbiological characterization of invasive group a Streptococcus infection in children in Japan: A single-center experience., PMID:39549831

High-resolution cryo-EM analysis of a Streptococcus pyogenes M-protein/human plasminogen complex., PMID:39500317

Group A Streptococcus vulvovaginitis in Spain, 2011-2023: antibiotic resistance and emm-type distribution., PMID:39480589

M proteins of group A Streptococcus bind hyaluronic acid via arginine-arginine/serine-arginine motifs., PMID:39436142

Serological Responses to Target Streptococcus pyogenes Vaccine Antigens in Patients With Proven Invasive β-Hemolytic Streptococcal Infections., PMID:39383256

A Rapid Molecular Detection Tool for Toxigenic M1UK  Streptococcus pyogenes., PMID:39206960

Nationwide upsurge in invasive disease in the context of longitudinal surveillance of carriage and invasive Streptococcus pyogenes 2009-2023, the Netherlands: a molecular epidemiological study., PMID:39194268

An acute rheumatic fever immune signature comprising inflammatory markers, IgG3, and Streptococcus pyogenes-specific antibodies., PMID:39184444

Immunogenicity of a 30-valent M protein mRNA group A Streptococcus vaccine., PMID:39141987

Molecular characterization of Streptococcus pyogenes (StrepA) non-invasive isolates during the 2022-2023 UK upsurge., PMID:39133528

Dihydrothiazolo ring-fused 2-pyridone antimicrobial compounds treat Streptococcus pyogenes skin and soft tissue infection., PMID:39093975

[Prevalence of the M1UK sublineage among emm1 Streptococcus pyogenes invasive strains isolated in the Czech Republic from December 2022 to May 2023]., PMID:39060098

Molecular Methods Enhance the Detection of Pyoderma-Related Streptococcus pyogenes and emm-Type Distribution in Children., PMID:39008379

Divergent effects of emm types 1 and 12 on invasive group A streptococcal infections-results of a retrospective cohort study, Germany 2023., PMID:38990040

Emergent emm4 group A Streptococcus evidences a survival strategy during interaction with immune effector cells., PMID:38888310

Conservation of C4BP-binding sequence patterns in Streptococcus pyogenes M and Enn proteins., PMID:38879009

Chimeric hepatitis B surface antigen virus-like particles expressing the strep A epitope p*17 elicit a humoral immune response in mice., PMID:38765111

Global epidemiological comparison of Streptococcus pyogenes emm-types associated with pharyngitis and pharyngeal carriage., PMID:38759867

[A rare cause of acute abdomen in a young immunocompetent woman]., PMID:38748278

The hinge-engineered IgG1-IgG3 hybrid subclass IgGh47 potently enhances Fc-mediated function of anti-streptococcal and SARS-CoV-2 antibodies., PMID:38678029

Efficacy of Alum-Adjuvanted Peptide and Carbohydrate Conjugate Vaccine Candidates against Group A Streptococcus Pharyngeal Infection in a Non-Human Primate Model., PMID:38675764

Recombinational exchange of M-fibril and T-pilus genes generates extensive cell surface diversity in the global group A Streptococcus population., PMID:38587426

Quantification of Adaptive Immune Responses Against Protein-Binding Interfaces in the Streptococcal M1 Protein., PMID:38527648

Streptococcal Toxic Shock Syndrome Caused by a Streptococcus pyogenes emm22 Genotype with a CsrS Mutation: a Case Report., PMID:38417865

Dihydrothiazolo ring-fused 2-pyridone antimicrobial compounds treat Streptococcus pyogenes skin and soft tissue infection., PMID:38260261

Molecular characterization of the interaction between human IgG and the M-related proteins from Streptococcus pyogenes., PMID:38176650

Population of invasive group A streptococci isolates from a German tertiary care center is dominated by the hypertoxigenic virulent M1UK genotype., PMID:38064158

A novel invasive Streptococcus pyogenes variant sublineage derived through recombinational replacement of the emm12 genomic region., PMID:38057343

SIgA structures bound to Streptococcus pyogenes M4 and human CD89 provide insights into host-pathogen interactions., PMID:37872175

Datasheet
$ 313
Product specifications
100 μg 313 1 mg 1629

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For research use only. Not for human or drug use.

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Recombinant Streptococcus pyogenes M protein Protein, N-His [YXX21703]
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