Catalog No.
EMB94002
Expression system
Insect Cells
Species
Mus musculus (Mouse)
Protein length
Met1-Asn108
Predicted molecular weight
13.13 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P01325
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Insulin-1, Insulin-1 B chain, Insulin-1 A chain, Ins1, Ins-1
CircCBP Inhibits Influenza A Virus Replication by Interfering the vRNP Activity and Enhancing Antiviral Immune Response., PMID:40503899
METRNL represses beta-to-alpha cell trans-differentiation to maintain beta cell function under diabetic metabolic stress in mice., PMID:40495021
Endoplasmic reticulum stress and forkhead box protein O1 inhibition mediate palmitic acid and high glucose-induced β-cell dedifferentiation., PMID:40487627
Time dynamics of elevated glucose and beta-hydroxybutyrate on beta cell mitochondrial metabolism., PMID:40387167
Ophiopogonin D improves pancreatic islet cell dedifferentiation to treat diabetes by regulating the GRP78/ROS/PDX1 signaling pathway., PMID:40365319
The Impact of Major and Minor Phytocannabinoids on the Maintenance and Function of INS-1 β-Cells Under High-Glucose and High-Lipid Conditions., PMID:40363798
The Beneficial Impact of a Novel Pancreatic Polypeptide Analogue on Islet Cell Lineage., PMID:40362452
Aldolase-regulated G3BP1/2+ condensates control insulin mRNA storage in beta cells., PMID:40355555
Circadian synchronization differentially modifies cytokine-mediated transcriptomic remodeling and cell death in INS-1 cells and mouse islets., PMID:40352732
Identification of RC3H1 as antiviral host factor binding to the non-structural protein 1 of Influenza A virus via a 3-stage computational pipeline and cell-based analysis., PMID:40287742
Molecular mapping and functional validation of GLP-1R cholesterol binding sites in pancreatic beta cells., PMID:40270220
Endogenous mucosal phosphatases characterization in duodenum brush border membrane of laying hens., PMID:40241716
Atractylenolide-Ⅲ binds non-structural protein-1 to suppress influenza A by modulating macrophage polarization and alternative polyadenylation., PMID:40220413
Malvidin-3-glucoside induces insulin secretion by activating the PLC/IP3 pathway and enhancing Ca2+ influx in INS-1 pancreatic β-cells., PMID:40216851
MIR192 Upregulates GLP-1 Receptor and Improves Statin-Induced Impairment of Insulin Secretion., PMID:40166140
Restriction of influenza A virus replication by host DCAF7-CRL4B axis., PMID:40145735
Evaluating Probenecid or Oseltamivir Inhibition of Influenza A Virus Replication Through Plaque Assay or Fluorescent Focus Assay Using Non-Structural Protein 1-H1N1 Venus Reporter Virus., PMID:40143264
Rhoifolin Improves Glycometabolic Control in Streptozotocin-Induced Diabetic Rats by Up-Regulating the Expression of Insulin Signaling Proteins and Down-Regulating the MAPK/JNK Pathway., PMID:40143138
Peptidylglycine alpha-amidating monooxygenase is important in mice for beta-cell cilia formation and insulin secretion but promotes diabetes risk through beta-cell independent mechanisms., PMID:40120979
In vitro and in vivo antidiabetic evaluation of new Coumarin and Chromone derivatives: Design, synthesis and molecular modeling., PMID:40101577
Nonstructural Protein 1 of Influenza A (NS1A) Demonstrates Strain-Specific dsRNA Binding Capabilities., PMID:40079391
TBC1D30 regulates proinsulin and insulin secretion and is the target of a genomic association signal for proinsulin., PMID:40064677
Eukaryotic RNA binding protein hnRNPH1 suppresses influenza A virus replication through interaction with virus NS1 protein., PMID:40052960
Klotho protects INS-1 pancreatic β-cells from senescence and enhances mitochondrial function., PMID:40018267
Evolutionary rewiring of the dynamic network underpinning allosteric epistasis in NS1 of the influenza A virus., PMID:39977319
Molecular Observations on the Regulation of hIAPP Aggregation Process and Enhancement of Autophagy by the Short Peptide LPFYPN and Its Modified Peptides of Coix Seed Prolamins., PMID:39950826
Increased Steroidogenic Acute Regulatory Protein Contributes to Cholesterol-induced β-Cell Dysfunction., PMID:39928527
Biochemical and biophysical characterization of inositol-tetrakisphosphate 1-kinase inhibitors., PMID:39922495
Cab45G trafficking through the insulin secretory pathway is altered in human type 2 diabetes., PMID:39898024
An Underlying Mechanism for the Altered Hypoglycemic Effects of Nateglinide in Rats with Acute Peripheral Inflammation., PMID:39880623
Vitamin D augments insulin secretion via calcium influx and upregulation of voltage calcium channels: Findings from INS-1 cells and human islets., PMID:39864489
DOC2b enrichment mitigates proinflammatory cytokine-induced CXCL10 expression by attenuating IKKβ and STAT-1 signaling in human islets., PMID:39805534
RTP4 restricts influenza A virus infection by targeting the viral NS1 protein., PMID:39798334
The Glucose-Lowering Effect of Mesembryanthemum crystallinum and D-Pinitol: Studies on Insulin Secretion in INS-1 Cells and the Reduction of Blood Glucose in Diabetic Rats., PMID:39796627
Single and Combined Impact of Semaglutide, Tirzepatide, and Metformin on β-Cell Maintenance and Function Under High-Glucose-High-Lipid Conditions: A Comparative Study., PMID:39796271
The Aryl Hydrocarbon Receptor (AhR) Is a Novel Gene Involved in Proper Physiological Functions of Pancreatic β-Cells., PMID:39791758
LGR4 is essential for maintaining β-cell homeostasis through suppression of RANK., PMID:39788290
DOC2b enrichment mitigates proinflammatory cytokine-induced CXCL10 expression by attenuating IKKβ and STAT-1 signaling in human islets., PMID:39763877
Implications of cyantraniliprole sublethal doses on the population dynamics and gene expression of Aphis gossypii Glover (Hemiptera: Aphididae)., PMID:39710084
Dexmedetomidine suppresses glucose-stimulated insulin secretion in pancreatic β-cells., PMID:39704036
[Salidroside alleviates high glucose and ethanol-induced pyroptosis in insulinoma cells]., PMID:39701714
Microfluidic chip systems for characterizing glucose-responsive insulin-secreting cells equipped with FailSafe kill-switch., PMID:39696686
NLRP3 inflammasome activation and disruption of IRS-1/PI3K/AKT signaling: Potential mechanisms of arsenic-induced pancreatic beta cells dysfunction in rats., PMID:39657381
Nitration of Tyr37 alters the aggregation pathway of hIAPP and enhances its cytotoxicity., PMID:39643176
Spint1 disruption in mouse pancreas leads to glucose intolerance and impaired insulin production involving HEPSIN/MAFA., PMID:39627229
Lipid droplet protein Perilipin 2 is critical for the regulation of insulin secretion through beta cell lipophagy and glucagon expression in pancreatic islets., PMID:39605485
1-Deoxynojirimycin affects high glucose-induced pancreatic beta-cell dysfunction through regulating CEBPA expression and AMPK pathway., PMID:39546764
Bioinformatics Analysis and Experimental Findings Reveal the Therapeutic Actions and Targets of Cyathulae Radix Against Type 2 Diabetes Mellitus., PMID:39534794
CD59 double knockout mice express a CD59ba hybrid fusion protein that mediates insulin secretion., PMID:39530539
Spirulina Unleashed: A Pancreatic Symphony to Restore Glycemic Balance and Improve Hyperlipidemia and Antioxidant Properties by Transcriptional Modulation of Genes in a Rat Model., PMID:39517296
For research use only. Not for human or drug use.
