Research Grade Anrukinzumab (DHE07706)

Catalog No.

DHE07706

Expression system

Mammalian Cells

Species reactivity

Human

Host species

Humanized

Isotype

IgG1-kappa

Clonality

Monoclonal

Target

IL13, NC30, Interleukin-13, IL-13

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P35225

Applications

Research Grade Biosimilar

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Alternative Names

IMA-638, CAS: 910649-32-0

Clone ID

Anrukinzumab

A Critical Evaluation of Anti-IL-13 and Anti-IL-4 Strategies in Severe Asthma, PMID: 27637004

A mechanistic PK/PD model for two anti-IL13 antibodies explains the difference in total IL-13 accumulation observed in clinical studies, PMID: 27049478

A pharmacokinetic comparison of anrukinzumab, an anti- IL-13 monoclonal antibody, among healthy volunteers, asthma and ulcerative colitis patients, PMID: 25614144

Anrukinzumab, an anti-interleukin 13 monoclonal antibody, in active UC: efficacy and safety from a phase IIa randomised multicentre study, PMID: 25567115

Modulating Interleukins and their Receptors Interactions with Small Chemicals Using In Silico Approach for Asthma, PMID: 30068279

The role of interleukin-13 in chronic inflammatory intestinal disorders, PMID: 30844559

Document Download

Research Grade Anrukinzumab.pdf