Catalog No.
YHA25501
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Asp60-Cys143
Predicted molecular weight
38.06 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O14645
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Axonemal dynein light intermediate polypeptide 1, Inner dynein arm light chain, axonemal, hp28, DNALI1
Cilia Plays a Pivotal Role in the Hypersecretion of Airway Mucus in Mice., PMID:40231527
Deficiency in DNAH12 causes male infertility by impairing DNAH1 and DNALI1 recruitment in humans and mice., PMID:40146200
LRRC56 deletion causes primary ciliary dyskinesia in mice characterized by dynein arms defects., PMID:39912490
DNAH3 deficiency causes flagellar inner dynein arm loss and male infertility in humans and mice., PMID:39503742
Exploring nasopharyngeal carcinoma genetics: Bioinformatics insights into pathways and gene associations., PMID:39352166
Primary Ciliary Dyskinesia Associated Disease-Causing Variants in CCDC39 and CCDC40 Cause Axonemal Absence of Inner Dynein Arm Heavy Chains DNAH1, DNAH6, and DNAH7., PMID:39056782
Application of sperm motion kinematics and motility-related proteins for prediction of male fertility., PMID:38359560
DNALI1 Promotes Neurodegeneration after Traumatic Brain Injury via Inhibition of Autophagosome-Lysosome Fusion., PMID:38348540
Dnali1 is required for sperm motility and male fertility in mice., PMID:37993789
Novel axonemal protein ZMYND12 interacts with TTC29 and DNAH1, and is required for male fertility and flagellum function., PMID:37934199
Dynein axonemal heavy chain 10 deficiency causes primary ciliary dyskinesia in humans and mice., PMID:37314648
Identification of hub genes associated with head and neck squamous cell carcinoma by integrated bioinformatics approach and RNA-seq validation analysis., PMID:37168331
DNALI1 interacts with the MEIG1/PACRG complex within the manchette and is required for proper sperm flagellum assembly in mice., PMID:37083624
miR-34a-5p as molecular hub of pathomechanisms in Huntington's disease., PMID:37013480
Comparative transcriptome analysis identified crucial genes and pathways affecting sperm motility in the reproductive tract of drakes with different libido., PMID:36881978
DNALI1 deficiency causes male infertility with severe asthenozoospermia in humans and mice by disrupting the assembly of the flagellar inner dynein arms and fibrous sheath., PMID:36792588
Homozygous mutation in DNALI1 leads to asthenoteratozoospermia by affecting the inner dynein arms., PMID:36726469
Subtyping children with asthma by clustering analysis of mRNA expression data., PMID:36159986
Functional analysis of the 1p34.3 risk locus implicates GNL2 in high-grade serous ovarian cancer., PMID:34965383
CCDC114, DNAI2 and TOP2A involves in the effects of tibolone treatment on postmenopausal endometrium., PMID:34116668
Novel Biallelic DNAH1 Variations Cause Multiple Morphological Abnormalities of the Sperm Flagella., PMID:33989052
Sexually dimorphic expression and regulatory sequence of dnali1 in the olive flounder Paralichthys olivaceus., PMID:33877529
Differential expression analysis and identification of sex-related genes by gonad transcriptome sequencing in estradiol-treated and non-treated Ussuri catfish Pseudobagrus ussuriensis., PMID:33523351
Immunofluorescence Analysis as a Diagnostic Tool in a Spanish Cohort of Patients with Suspected Primary Ciliary Dyskinesia., PMID:33182294
Integrated analysis of proteomics and metabolomics reveals the potential sex determination mechanism in Odontobutis potamophila., PMID:31401171
Dysregulation of sputum columnar epithelial cells and products in distinct asthma phenotypes., PMID:31264263
Transcription factor TAp73 and microRNA-449 complement each other to support multiciliogenesis., PMID:31068677
Bioinformatic identification of candidate biomarkers and related transcription factors in nasopharyngeal carcinoma., PMID:30935420
CFAP300: Mutations in Slavic Patients with Primary Ciliary Dyskinesia and a Role in Ciliary Dynein Arms Trafficking., PMID:30916986
Downregulation and Aberrant Localization of Forkhead Box J1 in Allergic Nasal Mucosa., PMID:29635245
ZMYND10 is mutated in primary ciliary dyskinesia and interacts with LRRC6., PMID:23891469
Deletions and point mutations of LRRC50 cause primary ciliary dyskinesia due to dynein arm defects., PMID:19944400
Gene expression analysis of frontotemporal lobar degeneration of the motor neuron disease type with ubiquitinated inclusions., PMID:17569064
The murine Dnali1 gene encodes a flagellar protein that interacts with the cytoplasmic dynein heavy chain 1., PMID:16496424
For research use only. Not for human or drug use.
