Catalog No.
YHA25501
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Asp60-Cys143
Predicted molecular weight
38.06 kDa
Nature
Recombinant
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
O14645
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Axonemal dynein light intermediate polypeptide 1, Inner dynein arm light chain, axonemal, hp28, DNALI1
Note
For research use only.
The murine Dnali1 gene encodes a flagellar protein that interacts with the cytoplasmic dynein heavy chain 1., PMID:16496424
Gene expression analysis of frontotemporal lobar degeneration of the motor neuron disease type with ubiquitinated inclusions., PMID:17569064
Deletions and point mutations of LRRC50 cause primary ciliary dyskinesia due to dynein arm defects., PMID:19944400
ZMYND10 is mutated in primary ciliary dyskinesia and interacts with LRRC6., PMID:23891469
Downregulation and Aberrant Localization of Forkhead Box J1 in Allergic Nasal Mucosa., PMID:29635245
CFAP300: Mutations in Slavic Patients with Primary Ciliary Dyskinesia and a Role in Ciliary Dynein Arms Trafficking., PMID:30916986
Bioinformatic identification of candidate biomarkers and related transcription factors in nasopharyngeal carcinoma., PMID:30935420
Transcription factor TAp73 and microRNA-449 complement each other to support multiciliogenesis., PMID:31068677
Dysregulation of sputum columnar epithelial cells and products in distinct asthma phenotypes., PMID:31264263
Integrated analysis of proteomics and metabolomics reveals the potential sex determination mechanism in Odontobutis potamophila., PMID:31401171
Immunofluorescence Analysis as a Diagnostic Tool in a Spanish Cohort of Patients with Suspected Primary Ciliary Dyskinesia., PMID:33182294
Differential expression analysis and identification of sex-related genes by gonad transcriptome sequencing in estradiol-treated and non-treated Ussuri catfish Pseudobagrus ussuriensis., PMID:33523351
Sexually dimorphic expression and regulatory sequence of dnali1 in the olive flounder Paralichthys olivaceus., PMID:33877529
Novel Biallelic DNAH1 Variations Cause Multiple Morphological Abnormalities of the Sperm Flagella., PMID:33989052
CCDC114, DNAI2 and TOP2A involves in the effects of tibolone treatment on postmenopausal endometrium., PMID:34116668
Functional analysis of the 1p34.3 risk locus implicates GNL2 in high-grade serous ovarian cancer., PMID:34965383
Subtyping children with asthma by clustering analysis of mRNA expression data., PMID:36159986
Homozygous mutation in DNALI1 leads to asthenoteratozoospermia by affecting the inner dynein arms., PMID:36726469
DNALI1 deficiency causes male infertility with severe asthenozoospermia in humans and mice by disrupting the assembly of the flagellar inner dynein arms and fibrous sheath., PMID:36792588
Comparative transcriptome analysis identified crucial genes and pathways affecting sperm motility in the reproductive tract of drakes with different libido., PMID:36881978
miR-34a-5p as molecular hub of pathomechanisms in Huntington's disease., PMID:37013480
DNALI1 interacts with the MEIG1/PACRG complex within the manchette and is required for proper sperm flagellum assembly in mice., PMID:37083624
Identification of hub genes associated with head and neck squamous cell carcinoma by integrated bioinformatics approach and RNA-seq validation analysis., PMID:37168331
Dynein axonemal heavy chain 10 deficiency causes primary ciliary dyskinesia in humans and mice., PMID:37314648
Novel axonemal protein ZMYND12 interacts with TTC29 and DNAH1, and is required for male fertility and flagellum function., PMID:37934199
Dnali1 is required for sperm motility and male fertility in mice., PMID:37993789
DNALI1 Promotes Neurodegeneration after Traumatic Brain Injury via Inhibition of Autophagosome-Lysosome Fusion., PMID:38348540
Application of sperm motion kinematics and motility-related proteins for prediction of male fertility., PMID:38359560
Primary Ciliary Dyskinesia Associated Disease-Causing Variants in CCDC39 and CCDC40 Cause Axonemal Absence of Inner Dynein Arm Heavy Chains DNAH1, DNAH6, and DNAH7., PMID:39056782
Exploring nasopharyngeal carcinoma genetics: Bioinformatics insights into pathways and gene associations., PMID:39352166
DNAH3 deficiency causes flagellar inner dynein arm loss and male infertility in humans and mice., PMID:39503742
LRRC56 deletion causes primary ciliary dyskinesia in mice characterized by dynein arms defects., PMID:39912490
Deficiency in DNAH12 causes male infertility by impairing DNAH1 and DNALI1 recruitment in humans and mice., PMID:40146200
Cilia Plays a Pivotal Role in the Hypersecretion of Airway Mucus in Mice., PMID:40231527
For research use only. Not for human or drug use.
