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Recombinant HCMV/HHV-5 UL123/IE1 Protein, N-GST & C-His

Catalog #:   YVV37301 Specific References (24) DATASHEET
Applications: ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Expression system: E. coli
Accession: AMO64957.1
Protein length: Asp12-Glu382
Overview

Catalog No.

YVV37301

Expression system

E. coli

Species

Human cytomegalovirus (HCMV/HHV-5)

Protein length

Asp12-Glu382

Predicted molecular weight

70.60 kDa

Nature

Recombinant

Endotoxin level

Please contact with the lab for this information.

Purity

>90% as determined by SDS-PAGE.

Accession

AMO64957.1

Applications

ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress

Form

Lyophilized

Storage buffer

Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.

Reconstitution

Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.

Shipping

In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Alternative Names

regulatory protein IE1, UL123

Data Image
  • SDS-PAGE
    SDS-PAGE for Recombinant Human betaherpesvirus 5 (HHV-5) UL123/IE1 protein
References

Triple lysine and nucleosome-binding motifs of the viral IE19 protein are required for human cytomegalovirus S-phase infections., PMID:38695580

Structure elucidation and antiviral activity of a cold water-extracted mannogalactofucan Ts1-1A from Trametes sanguinea against human cytomegalovirus in vitro., PMID:38616079

Human MicroRNAs Attenuate the Expression of Immediate Early Proteins and HCMV Replication during Lytic and Latent Infection in Connection with Enhancement of Phosphorylated RelA/p65 (Serine 536) That Binds to MIEP., PMID:35269913

Productive Infection of Human Breast Cancer Cell Lines with Human Cytomegalovirus (HCMV)., PMID:34070980

Cytomegalovirus Immediate-Early Proteins Promote Stemness Properties in Glioblastoma., PMID:26239477

Natural antisense transcripts of UL123 packaged in human cytomegalovirus virions., PMID:23884634

Allitridin inhibits human cytomegalovirus replication in vitro., PMID:23426791

Tissue and cell-specific transcriptional activity of the human cytomegalovirus immediate early gene promoter (UL123) in zebrafish., PMID:23347918

Coordination of late gene transcription of human cytomegalovirus with viral DNA synthesis: recombinant viruses as potential therapeutic vaccine candidates., PMID:23231449

RNA interference-mediated targeting of human cytomegalovirus immediate-early or early gene products inhibits viral replication with differential effects on cellular functions., PMID:22438545

Human cytomegalovirus infection alters PC3 prostate carcinoma cell adhesion to endothelial cells and extracellular matrix., PMID:17032497

Human cytomegalovirus IE1-72 activates ataxia telangiectasia mutated kinase and a p53/p21-mediated growth arrest response., PMID:16103197

Human cytomegalovirus proteins pp65 and immediate early protein 1 are common targets for CD8+ T cell responses in children with congenital or postnatal human cytomegalovirus infection., PMID:14764694

Human cytomegalovirus proteins PP65 and IEP72 are targeted to distinct compartments in nuclei and nuclear matrices of infected human embryo fibroblasts., PMID:14624464

Human cytomegalovirus enhances chemokine production by lipopolysaccharide-stimulated lamina propria macrophages., PMID:11865414

Quantitative competitive NASBA for measuring mRNA expression levels of the immediate early 1, late pp67, and immune evasion genes US3, US6 and US11 in cells infected with human cytomegalovirus., PMID:11445144

Direct quantification of human cytomegalovirus immediate-early and late mRNA levels in blood of lung transplant recipients by competitive nucleic acid sequence-based amplification., PMID:11136779

Disruption of PML-associated nuclear bodies by IE1 correlates with efficient early stages of viral gene expression and DNA replication in human cytomegalovirus infection., PMID:10936087

Strong conservation of the constitutive activity of the IE1/2 transcriptional control region in wild-type strains of human cytomegalovirus., PMID:9880020

The N-terminal 303 amino acids of the human cytomegalovirus envelope glycoprotein B (UL55) and the exon 4 region of the major immediate early protein 1 (UL123) induce a cytotoxic T-cell response., PMID:8735546

Multiple regulatory events influence human cytomegalovirus DNA polymerase (UL54) expression during viral infection., PMID:8523551

The dominant phosphoprotein pp65 (UL83) of human cytomegalovirus is dispensable for growth in cell culture., PMID:7666500

Structural Organization of the Spliced Immediate-Early Gene Complex that Encodes the Major Acidic Nuclear (IE1) and Transactivator (IE2) Proteins of African Green Monkey Cytomegalovirus., PMID:11725047

Humoral immune response against human cytomegalovirus (HCMV)-specific proteins after HCMV infection in lung transplantation as detected with recombinant and naturally occurring proteins., PMID:7535179

Datasheet
$ 313
Product specifications
100 μg 313 1 mg 1629

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For research use only. Not for human or drug use.

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Recombinant HCMV/HHV-5 UL123/IE1 Protein, N-GST & C-His [YVV37301]
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