Catalog No.
YRN44701
Expression system
E. coli
Species
Rattus norvegicus (Rat)
Protein length
Arg26-Lys218
Predicted molecular weight
25 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q8VI81
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Fibroblast growth factor, FGF, Fgf19, FGF15, Fgf8a
Lactobacillus rhamnosus GG maintains gut microbiota stability and promotes intestinal adaptation via activated intestinal farnesoid X receptor signaling in short bowel syndrome., PMID:40425822
ZeXieYin formula alleviates atherosclerosis by regulating SBAs levels through the FXR/FGF15 pathway and restoring intestinal barrier integrity., PMID:40414923
Inhibition of Farnesoid-x-receptor signaling during abdominal sepsis by dysbiosis exacerbates gut barrier dysfunction., PMID:40399878
Platycodonis radix polysaccharides suppress progression of high-fat-induced obesity through modulation of intestinal microbiota and metabolites., PMID:40354675
Hepatic and intestinal tissue-specific Fxr deficiency alters bile acid homeostasis in female mice., PMID:40338063
Salvianolic acid B attenuates hypercholesterolemia via modulating the gut microbiota and bile acid metabolism., PMID:40334726
Epiberberine ameliorates ulcerative colitis by regulating bile acids hepatoenteral circulation through intestinal FXR., PMID:40334429
The role of gut microbiota on skeletal muscle strength in LDLR knockdown aging mice., PMID:40312444
Suppressed intestinal secondary bile acids in moxifloxacin-induced hyperglycemia: studies in normal and diabetic GK rats., PMID:40255568
Gut Microbiota and Its Metabolite Taurine-β-Muricholic Acid Contribute to Antimony- and/or Copper-Induced Liver Inflammation., PMID:40244173
Lactococcus petauri LZys1 modulates gut microbiota, diminishes ileal FXR-FGF15 signaling, and regulates hepatic function., PMID:40243350
Schisandra chinensis lignans ameliorate hepatic inflammation and steatosis in methionine choline-deficient diet-fed mice by modulating the gut-liver axis., PMID:40222688
Nobiletin Enhances Skeletal Muscle Mass and Modulates Bile Acid Composition in Diet-Induced Obese Mice., PMID:40193085
Farnesoid X Receptor Regulated Sepsis-Induced Abnormal Bile Acid Metabolism via the Fibroblast Growth Factor 15/Fibroblast Growth Factor Receptor 4 Pathway., PMID:40192065
Short-chain fatty acids alleviate cholestatic liver injury by improving gut microbiota and bile acid metabolism., PMID:40186906
Alterations in intestinal bile acid transport provide a therapeutic target in patients with post-bariatric hypoglycaemia., PMID:40186075
Triterpenoids from ilicis rotundae cortex ameliorate hyperlipidemia by affecting bile acids-hepatointestinal FXR axis., PMID:40023069
Oat β-glucan prevents high fat diet induced obesity by targeting ileal Farnesoid X receptor-fibroblast growth factor 15 signaling., PMID:40020836
Alpha-aminobutyric acid ameliorates diet-induced metabolic dysfunction-associated steatotic liver disease (MASLD) progression in mice via enhancing AMPK/SIRT1 pathway and modulating the gut-liver axis., PMID:40015656
Activation of gut FXR improves the metabolism of bile acids, intestinal barrier, and microbiota under cholestatic condition caused by GCDCA in mice., PMID:39982108
Sanye tablet regulates gut microbiota and bile acid metabolism to attenuate hepatic steatosis., PMID:39971018
High-fat diet promotes gestational diabetes mellitus through modulating gut microbiota and bile acid metabolism., PMID:39935515
Galactooligosaccharide-Metabolism-Related Genes of Bifidobacterium pseudocatenulatum Contribute to the Regulation of Glucose and Lipid Metabolism in Type 2 Diabetic Mice., PMID:39801054
Deficiency of Epithelial PIEZO1 Alleviates Liver Steatosis Induced by High-Fat Diet in Mice., PMID:39781454
Ramulus Mori (Sangzhi) alkaloids ameliorate high-fat diet induced obesity in rats by modulating gut microbiota and bile acid metabolism., PMID:39758340
FGF19-Activated Hepatic Stellate Cells Release ANGPTL4 that Promotes Colorectal Cancer Liver Metastasis., PMID:39716892
Clostridium Scindens Protects Against Vancomycin-Induced Cholestasis and Liver Fibrosis by Activating Intestinal FXR-FGF15/19 Signaling., PMID:39680750
High-fat/high-sucrose diet results in a high rate of MASH with HCC in a mouse model of human-like bile acid composition., PMID:39670881
Ginsenosides From Panax ginseng Improves Hepatic Lipid Metabolism Disorders in HFD-Fed Rats by Regulating Gut Microbiota and Cholesterol Metabolism Signaling Pathways., PMID:39660634
Integrating network pharmacology and animal experimental validation to investigate the mechanism of lotus leaf in obesity., PMID:39647284
Liver-gut axis signaling regulates circadian energy metabolism in shift workers., PMID:39588921
Overexpression of TNFα in TNF∆ARE+/- mice increases hepatic periportal inflammation and alters bile acid signaling in mice., PMID:39585296
The role of FGF15/FGF19 in the development of the central nervous system, eyes and inner ears in vertebrates., PMID:39579736
Identification of chikusetsusaponin IVa as a novel lysine-specific demethylase 1 inhibitor that ameliorates high fat diet-induced MASLD in mice., PMID:39567752
A primer on the pleiotropic endocrine fibroblast growth factor FGF19/FGF15., PMID:39500656
Low polarity fraction of Radix Bupleuri alleviates chronic unpredictable mild stress-induced depression in rats through FXR modulating bile acid homeostasis in liver, gut, and brain., PMID:39489929
Abnormal enterohepatic circulation of bile acids caused by fructooligosaccharide supplementation along with a high-fat diet., PMID:39450588
The total alkaloids of Berberidis Cortex alleviate type 2 diabetes mellitus by regulating gut microbiota, inflammation and liver gluconeogenesis., PMID:39426578
Hepatic FXR-FGF4 is required for bile acid homeostasis via an FGFR4-LRH-1 signal node under cholestatic stress., PMID:39393353
Parenteral nutrition results in peripheral ileal to hepatic circadian discordance in mice., PMID:39301965
Characterization of FGF21 Sites of Production and Signaling in Mice., PMID:39253796
Lactobacillus acidophilus ameliorates cholestatic liver injury through inhibiting bile acid synthesis and promoting bile acid excretion., PMID:39205654
Yellow tea polysaccharides protect against non-alcoholic fatty liver disease via regulation of gut microbiota and bile acid metabolism in mice., PMID:39153277
Gut-muscle communication links FGF19 levels to the loss of lean muscle mass following rapid weight loss., PMID:39134173
Perfluorooctanoic acid (PFOA) and its alternative perfluorobutanoic acid (PFBA) alter hepatic bile acid profiles via different pathways., PMID:39122034
Fluoride induces hepatointestinal damage and vitamin B2 mitigation by regulating IL-17A and Bifidobacterium in ileum., PMID:39097090
Endocrine fibroblast growth factors in domestic animals., PMID:39059301
Nuclear factor interleukin 3 and metabolic dysfunction-associated fatty liver disease development., PMID:39048678
Bile Acid Injection Regulated Blood Glucose in T2DM Rats Via the TGR5/GLP-1 Rather than FXR/FGF15 Pathway., PMID:39038352
Pulsatilla decoction alleviates DSS-induced UC by activating FXR-ASBT pathways to ameliorate disordered bile acids homeostasis., PMID:38974033
For research use only. Not for human or drug use.
