Anti-Human CADM3/NECL-1/TSLL1 Polyclonal Antibody

Catalog No.

PHK84301

Species reactivity

Human

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human CADM3/NECL-1/TSLL1 (Asn25-His330).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

TSLL1, Immunoglobulin superfamily member 4B, Brain immunoglobulin receptor, NECL1, CADM3, Synaptic cell adhesion molecule 3, Cell adhesion molecule 3, IgSF4B, NECL-1, Nectin-like protein 1, TSLC1-like protein 1, SynCAM3, SYNCAM3, IGSF4B

Purification

Purified by antigen affinity column.

Accession

Q8N126

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Clinical significance of low expression of CADM3 in breast cancer and preliminary exploration of related mechanisms., PMID:38515057

Pseudo-Dystonia and Marked Intrafamilial Variability in CADM3-Related Disease., PMID:37196599

Circ004463 promotes fibroblast proliferation and collagen I synthesis by sponging miR-23b and regulating CADM3/MAP4K4 via activation of AKT/ERK pathways., PMID:36502948

Cataloguing experimentally confirmed 80.7 kb-long ACKR1 haplotypes from the 1000 Genomes Project database., PMID:34039276

A CADM3 variant causes Charcot-Marie-Tooth disease with marked upper limb involvement., PMID:33889941

Differential Contribution of Cadm1-Cadm3 Cell Adhesion Molecules to Peripheral Myelinated Axons., PMID:33397712

Undifferentiated pleomorphic sarcomas with PRDM10 fusions have a distinct gene expression profile., PMID:31313299

Mass spectrometry-based analysis of cerebrospinal fluid from arthritis patients-immune-related candidate proteins affected by TNF blocking treatment., PMID:30770760

Necl-4/Cadm4 recruits Par-3 to the Schwann cell adaxonal membrane., PMID:30585357

miR-140-5p suppresses retinoblastoma cell proliferation, migration, and invasion by targeting CEMIP and CADM3., PMID:29808799

Cadm3 (Necl-1) interferes with the activation of the PI3 kinase/Akt signaling cascade and inhibits Schwann cell myelination in vitro., PMID:27658374

Label-Free LC-MS/MS Proteomic Analysis of Cerebrospinal Fluid Identifies Protein/Pathway Alterations and Candidate Biomarkers for Amyotrophic Lateral Sclerosis., PMID:26401960

Genetic deletion of Cadm4 results in myelin abnormalities resembling Charcot-Marie-Tooth neuropathy., PMID:23825401

Synaptic adhesion molecules in Cadm family at the neuromuscular junction., PMID:23505055

Localization of Cadm2a and Cadm3 proteins during development of the zebrafish nervous system., PMID:21456004

Embryonic corneal Schwann cells express some Schwann cell marker mRNAs, but no mature Schwann cell marker proteins., PMID:19387082

Loss of NECL1, a novel tumor suppressor, can be restored in glioma by HDAC inhibitor-Trichostatin A through Sp1 binding site., PMID:19062177

Nectin-like molecule 1 is a glycoprotein with a single N-glycosylation site at N290KS which influences its adhesion activity., PMID:18420026

Crystal structure of the V domain of human Nectin-like molecule-1/Syncam3/Tsll1/Igsf4b, a neural tissue-specific immunoglobulin-like cell-cell adhesion molecule., PMID:16467305

Isolation of the TSLL1 and TSLL2 genes, members of the tumor suppressor TSLC1 gene family encoding transmembrane proteins., PMID:11536053

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