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Research Grade Enlimomab (DHC16002)

Host species:Mouse
Isotype:IgG2a-nd
Applications:Research Grade Biosimilar
Expression system:Mammalian Cells
Overview

Catalog No.

DHC16002

Expression system

Mammalian Cells

Species reactivity

Human

Host species

Mouse

Isotype

IgG2a-nd

Clonality

Monoclonal

Target

ICAM1, Major group rhinovirus receptor, CD54, ICAM-1, Intercellular adhesion molecule 1

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P05362

Applications

Research Grade Biosimilar

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Alternative Names

BI-RR-1, BIRR-1, CAS: 142864-19-5

Clone ID

Enlimomab

Data Image
  • SDS-PAGE
    SDS PAGE for Enlimomab
  • Bioactivity
    Detects CD54/ICAM1 in indirect ELISAs.
  • SEC-HPLC
    The purity of this product is >95% as determined by SEC-HPLC.
References

Safety, pharmacokinetics and biological activity of enlimomab (anti-ICAM-1 antibody): an open-label, dose escalation study in patients hospitalized for acute stroke, PMID: 9693236

Use of anti-ICAM-1 therapy in ischemic stroke: results of the Enlimomab Acute Stroke Trial, PMID: 11673584

A randomized multicenter trial of the anti-ICAM-1 monoclonal antibody (enlimomab) for the prevention of acute rejection and delayed onset of graft function in cadaveric renal transplantation: a report of the European Anti-ICAM-1 Renal Transplant Study Group, PMID: 10096530

Anti-leukocyte antibodies: LeukArrest (Hu23F2G) and Enlimomab (R6.5) in acute stroke, PMID: 12365824

Anti-ICAM-1 monoclonal antibody R6.5 (Enlimomab) promotes activation of neutrophils in whole blood, PMID: 9973515

Examination of several potential mechanisms for the negative outcome in a clinical stroke trial of enlimomab, a murine anti-human intercellular adhesion molecule-1 antibody: a bedside-to-bench study, PMID: 11692032

Clinical effects of inhibiting leukocyte adhesion with monoclonal antibody to intercellular adhesion molecule-1 (enlimomab) in the treatment of partial-thickness burn injury, PMID: 12777909

Inflammation as a therapeutic target in acute ischemic stroke treatment, PMID: 19849665

Neuroprotective agents in acute ischemic stroke, PMID: 12038658

Acute anti-inflammatory approaches to ischemic stroke, PMID: 20955437

The role of inflammation after acute stroke: utility of pursuing anti-adhesion molecule therapy, PMID: 9744839

Datasheet

Document Download

Research Grade Enlimomab.pdf

 

$ 328
Product specifications
100 μg 328 1 mg 1314

Contact Information

Order: order@antibodysystem.com

Mail: support@antibodysystem.com

Distributor list

For research use only. Not for human or drug use.

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Research Grade Enlimomab [DHC16002]
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