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Anti-Beta-2 adrenergic receptor Antibody (N430/26)

Catalog #:   RHC26905 Specific References (50) DATASHEET
Host species: Mouse
Isotype: IgG2a, kappa
Applications: IHC, WB
Overview

Catalog No.

RHC26905

Host species

Mouse

Isotype

IgG2a, kappa

Clonality

Monoclonal

Target

Beta-2 adrenergic receptor, ADRB2R, Beta-2 adrenoreceptor, ADRB2, B2AR, Beta-2 adrenoceptor

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Applications

IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

N430/26

Data Image
References

Circulating Autoantibodies Against Vasoactive Biomarkers Related to Orthostatic Intolerance in Long COVID Patients Compared to No-Long-COVID Populations: A Case-Control Study., PMID:40001603

Stress-experienced monocytes/macrophages lose anti-inflammatory function via β2-adrenergic receptor in skin allergic inflammation., PMID:39566608

Impact of Tumoral β2-Adrenergic Receptor Expression on Chemotherapeutic Response and Prognosis in Patients with Advanced Colorectal Cancer., PMID:39341920

Ligand-independent function of β2-adrenergic receptor affects IgE-mediated Ca2+ influx in mast cells., PMID:39191189

Identification of adrenergic presynaptic and postsynaptic protein locations at neuromuscular junctions, their decrease during aging, and recovery by nicotinamide mononucleotide administration., PMID:38935067

Optical control of nanobody-mediated protein activity modulation with a photocleavable fluorescent protein., PMID:38916284

β2-adrenergic receptor activation decreases the mechanical sensitivity of rat masticatory muscle afferent fibres., PMID:38894554

Increase of Cardiac Autoantibodies Against Beta-2-adrenergic Receptor During Acute Cellular Heart Transplant Rejection., PMID:38773844

Computational Modeling and Characterization of Peptides Derived from Nanobody Complementary-Determining Region 2 (CDR2) Targeting Active-State Conformation of the β2-Adrenergic Receptor (β2AR)., PMID:38672440

Exercise-induced β2-adrenergic Receptor Activation Enhances the Antileukemic Activity of Expanded γδ T-Cells via DNAM-1 Upregulation and PVR/Nectin-2 Recognition., PMID:38592213

Reply to: How carvedilol does not activate β2-adrenoceptors., PMID:38036502

β2-AR inhibition enhances EGFR antibody efficacy hampering the oxidative stress response machinery., PMID:37723219

β2-adrenergic receptor expression in patients receiving bevacizumab therapy for metastatic melanoma., PMID:37551424

The β2-adrenergic receptor agonist terbutaline upregulates T helper-17 cells in a protein kinase A-dependent manner., PMID:37438188

β2-adrenergic signaling promotes higher-affinity B cells and antibodies., PMID:37369341

Adrenergic receptor signaling regulates the CD40-receptor mediated anti-tumor immunity., PMID:37006295

Clinical and prognostic associations of autoantibodies recognizing adrenergic/muscarinic receptors in patients with heart failure., PMID:36883593

Mechanistic Links Between Obesity and Airway Pathobiology Inform Therapies for Obesity-Related Asthma., PMID:36656428

How Carvedilol activates β2-adrenoceptors., PMID:36402762

Antiasthmatic Compounds Targeting β2-Adrenergic Receptor from Perilla frutescens Improved Lung Inflammation by Inhibiting the NF-κB Signaling Pathway., PMID:36322828

Beta-2 Adrenergic Receptor Gene Expression in HER2-Positive Early-Stage Breast Cancer Patients: A Post-hoc Analysis of the NCCTG-N9831 (Alliance) Trial., PMID:34980541

Two-point immobilization of a conformation-specific beta2-adrenoceptor for recognizing the receptor agonists or antagonists inspired by binding-induced DNA assembly., PMID:34704989

Agonistic β2-Adrenergic Receptor Autoantibodies Characterize the Aqueous Humor of Patients With Primary and Secondary Open-Angle Glaucoma., PMID:34025634

Agonistic autoantibodies against ß2-adrenergic receptor influence retinal microcirculation in glaucoma suspects and patients., PMID:33961631

Functional Autoreactive Anti-β2 Adrenergic Antibodies May Contribute to Insulin Resistance Profile in Patients with Chronic Chagas Disease., PMID:33801107

Importance of β2AR elevation for re-endothelialization capacity mediated by late endothelial progenitor cells in hypertensive patients., PMID:33356961

Role of β2-adrenergic receptors in chronic obstructive pulmonary disease., PMID:33301808

Modular transient nanoclustering of activated β2-adrenergic receptors revealed by single-molecule tracking of conformation-specific nanobodies., PMID:33214152

Therapeutic potential of muscle growth promoters in a stress urinary incontinence model., PMID:32686522

Molecular basis of β-arrestin coupling to formoterol-bound β1-adrenoceptor., PMID:32555462

Unmasking features of the auto-epitope essential for β1 -adrenoceptor activation by autoantibodies in chronic heart failure., PMID:32436653

β adrenergic receptor modulated signaling in glioma models: promoting β adrenergic receptor-β arrestin scaffold-mediated activation of extracellular-regulated kinase 1/2 may prove to be a panacea in the treatment of intracranial and spinal malignancy and extra-neuraxial carcinoma., PMID:32303958

A Unifying Hypothesis of the Pathophysiology of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS): Recognitions from the finding of autoantibodies against ß2-adrenergic receptors., PMID:32247028

The pharmacological management of asthma-chronic obstructive pulmonary disease overlap syndrome (ACOS)., PMID:31955671

β-blockers Reverse Agonist-Induced β2-AR Downregulation Regardless of Their Signaling Profile., PMID:31947522

Single-cell Analysis of β2-Adrenergic Receptor Dynamics by Quantitative Fluorescence Microscopy., PMID:31840614

Computational design and characterization of nanobody-derived peptides that stabilize the active conformation of the β2-adrenergic receptor (β2-AR)., PMID:31719570

Autoantibodies Activating the β2-Adrenergic Receptor Characterize Patients With Primary and Secondary Glaucoma., PMID:31632387

Optogenetic activation of intracellular antibodies for direct modulation of endogenous proteins., PMID:31611691

Bitter Taste Receptors for Asthma Therapeutics., PMID:31379597

Ventilation following established ARDS: a preclinical model framework to improve predictive power., PMID:31278170

Post-Mortem Immunohistochemical Evidence of β2-Adrenergic Receptor Expression in the Adrenal Gland., PMID:31234562

Engineering of Nanobodies Recognizing the Human Chemokine Receptor CCR7., PMID:31137829

No evidence for humoral autoimmunity against cardiomyocytes, adrenergic or muscarinic receptors in patients with Tako-Tsubo cardiomyopathy., PMID:30554740

Treadmill exercise restores high fat diet-induced disturbance of hippocampal neurogenesis through β2-adrenergic receptor-dependent induction of thioredoxin-1 and brain-derived neurotrophic factor., PMID:30496734

Synergistic Effects of Weightlessness, Isoproterenol, and Radiation on DNA Damage Response and Cytokine Production in Immune Cells., PMID:30469384

Structural insights into binding specificity, efficacy and bias of a β2AR partial agonist., PMID:30327561

Role of S1P/S1PR3 axis in release of CCL20 from human bronchial epithelial cells., PMID:30192865

Autoimmune Responses in Severe Asthma., PMID:30088364

Prevalence and Determinants of Agonistic Autoantibodies Against α1-Adrenergic Receptors in Patients Screened Positive for Dementia: Results from the Population-Based DelpHi-Study., PMID:30010118

Datasheet
$ 328
Product specifications
100 μg 328 1 mg 1640

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For research use only. Not for human or drug use.

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Anti-Beta-2 adrenergic receptor Antibody (N430/26) [RHC26905]
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