Catalog No.
PMF79701
Species reactivity
Mouse
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Mouse EFNB1 (Asn31-Gly165).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Ephrin-B1 (CEK5 receptor ligand) (CEK5-L) (EFL-3) (ELK ligand) (ELK-L) (EPH-related receptor tyrosine kinase ligand 2) (LERK-2) (Stimulated by retinoic acid gene 1 protein) [Cleaved into: Ephrin-B1 C-terminal fragment (Ephrin-B1 CTF), Ephrin-B1 intracellular domain (Ephrin-B1 ICD)]
Purification
Purified by antigen affinity column.
Accession
P52795
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Cdc42 Activation in Anti-nephrin Antibody-Induced Nephropathy., PMID:40459930
Ephrin-B1 regulates cell surface residency of heparan sulfate proteoglycans (HSPGs) and complexes with the HSPG CD44V3-10 and fibroblast growth factor receptors., PMID:40294072
Synbindin Downregulation Participates in Slit Diaphragm Dysfunction., PMID:34515036
The zinc fingers and homeoboxes 2 protein ZHX2 and its interacting proteins regulate upstream pathways in podocyte diseases., PMID:32059999
Abnormalities in cortical interneuron subtypes in ephrin-B mutant mice., PMID:29904965
Nephrin-Binding Ephrin-B1 at the Slit Diaphragm Controls Podocyte Function through the JNK Pathway., PMID:29602834
Role of EFNB1 and EFNB2 in Mouse Collagen-Induced Arthritis and Human Rheumatoid Arthritis., PMID:25779027
Stimulation of EphB2/ephrin-B1 signalling by tumour necrosis factor alpha in human dental pulp stem cells., PMID:25643922
Claudin-5 levels are reduced from multiple cell types in human failing hearts and are associated with mislocalization of ephrin-B1., PMID:25440958
The Eph tyrosine kinase receptors EphB2 and EphA2 are novel proteolytic substrates of tissue factor/coagulation factor VIIa., PMID:25281742
EphB2 contributes to human naive B-cell activation and is regulated by miR-185., PMID:24803541
Enhanced expression of EphrinB1 is associated with lymph node metastasis and poor prognosis in breast cancer., PMID:24240587
Targeting ERBB receptors shifts their partners and triggers persistent ERK signaling through a novel ERBB/EFNB1 complex., PMID:23811940
Targeted disruption of ephrin B1 in cells of myeloid lineage increases osteoclast differentiation and bone resorption in mice., PMID:22403721
Comparison of three quantitative phosphoproteomic strategies to study receptor tyrosine kinase signaling., PMID:22013880
Complementary expression and repulsive signaling suggest that EphB receptors and ephrin-B ligands control cell positioning in the gastric epithelium., PMID:21959989
Complementary expression of EphB receptors and ephrin-B ligand in the pyloric and duodenal epithelium of adult mice., PMID:21818578
Transsynaptic EphB/Ephrin-B signaling regulates growth of presynaptic boutons required for classical conditioning., PMID:21653848
Altered intestinal epithelial homeostasis in mice with intestine-specific deletion of the Krüppel-like factor 4 gene., PMID:21070761
Developmental expression of Eph and ephrin family genes in mammalian small intestine., PMID:20112066
Ephrin B1 regulates bone marrow stromal cell differentiation and bone formation by influencing TAZ transactivation via complex formation with NHERF1., PMID:19995908
Proteomics analysis of A33 immunoaffinity-purified exosomes released from the human colon tumor cell line LIM1215 reveals a tissue-specific protein signature., PMID:19837982
The phosphorylation of ephrin-B2 ligand promotes glioma cell migration and invasion., PMID:19728339
Therapeutic targets in the podocyte: findings in anti-slit diaphragm antibody-induced nephropathy., PMID:19662599
Slit diaphragm dysfunction in proteinuric states: identification of novel therapeutic targets for nephrotic syndrome., PMID:19266252
Enhancement of lymphocyte migration and cytokine production by ephrinB1 system in rheumatoid arthritis., PMID:17942634
EphrinB1-EphB signaling regulates thymocyte-epithelium interactions involved in functional T cell development., PMID:17668899
Ephrin-B1 localizes at the slit diaphragm of the glomerular podocyte., PMID:17667985
Ephrin-B2 forward signaling regulates somite patterning and neural crest cell development., PMID:17223098
EphB/ephrin-B interaction mediates adult stem cell attachment, spreading, and migration: implications for dental tissue repair., PMID:17204606
Distribution of EphB receptors and ephrin-B1 in the developing vertebrate spinal cord., PMID:16786562
Eph kinases and ephrins support thrombus growth and stability by regulating integrin outside-in signaling in platelets., PMID:15994237
Inhibition of integrin-mediated cell adhesion but not directional cell migration requires catalytic activity of EphB3 receptor tyrosine kinase. Role of Rho family small GTPases., PMID:15536074
The phosphorylation of EphB2 receptor regulates migration and invasion of human glioma cells., PMID:15126357
Ephrin B1 is expressed on human luteinizing granulosa cells in corpora lutea of the early luteal phase: the possible involvement of the B class Eph-ephrin system during corpus luteum formation., PMID:12970314
Human dendritic cells express neuronal Eph receptor tyrosine kinases: role of EphA2 in regulating adhesion to fibronectin., PMID:12907451
Control of hippocampal dendritic spine morphology through ephrin-A3/EphA4 signaling., PMID:12496762
Trans-synaptic Eph receptor-ephrin signaling in hippocampal mossy fiber LTP., PMID:12052960
Synergistic induction of tumor antigens by Wnt-1 signaling and retinoic acid revealed by gene expression profiling., PMID:11832495
Ephrins stimulate neurite outgrowth during early cortical neurogenesis., PMID:11746437
Ephrin B1 is expressed on neuroepithelial cells in correlation with neocortical neurogenesis., PMID:11306625
Tyrosine phosphorylation of the human guanylyl cyclase C receptor., PMID:11120586
Spinal motor axons and neural crest cells use different molecular guides for segmental migration through the rostral half-somite., PMID:10699981
Eph receptors and ephrins demarcate cerebellar lobules before and during their formation., PMID:10495276
Origins and formation of microvasculature in the developing kidney., PMID:9736245
Eph receptors discriminate specific ligand oligomers to determine alternative signaling complexes, attachment, and assembly responses., PMID:9499402
Ligand for EPH-related kinase (LERK) 7 is the preferred high affinity ligand for the HEK receptor., PMID:9195962
Lerk2 (ephrin-B1) is a collapsing factor for a subset of cortical growth cones and acts by a mechanism different from AL-1 (ephrin-A5)., PMID:9268508
Ligands for EPH-related receptor tyrosine kinases that require membrane attachment or clustering for activity., PMID:7973638
For research use only. Not for human or drug use.
