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Anti-Microcystin-LR/RR Antibody (MC10E7) (RGN10001)

Host species:Mouse
Isotype:IgG2a, kappa
Applications:ELISA, SPR
Accession:ChEBI: 6925
Overview

Catalog No.

RGN10001

Species reactivity

General

Host species

Mouse

Isotype

IgG2a, kappa

Clonality

Monoclonal

Target

MC-LR, Microcystin-LR, Microcystin LR, Microcystis aeruginosa toxin, Toxin-LR, Cyanoginosin LRMC-RR, Microcystin-RR, Microcystin RR, Cyanoginosin RR

Concentration

1.17 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

ChEBI: 6925

Applications

ELISA, SPR

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

MC10E7

Data Image
References

Cloning and plant-based production of antibody MC10E7 for a lateral flow immunoassay to detect [4-arginine]microcystin in freshwater. PMID: 28421663

Analysis of dissolved microcystins in surface water samples from Kovada Lake, Turkey. PMID: 19395066

Multidimensional biochemical detection of microcystins in liquid chromatography. PMID: 11816581

Microcystin-LR ameliorates pulmonary fibrosis via modulating CD206+ M2-like macrophage polarization. PMID: 32075954

The latest advances in the reproductive toxicity of microcystin-LR. PMID: 32991922

Immunoassay technology: Research progress in microcystin-LR detection in water samples. PMID: 34689091

Photocatalytic degradation of microcystin-LR by modified TiO2 photocatalysis: A review. PMID: 32673915

Determination of microcystin-LR, employing aptasensors. PMID: 30121422

Fenton-based technologies as efficient advanced oxidation processes for microcystin-LR degradation. PMID: 33207450

Microcystin-LR induces apoptosis in Juvenile Eriocheir sinensis via the mitochondrial pathway. PMID: 35500400

Mechanisms of microcystin-LR-induced cytoskeletal disruption in animal cells. PMID: 25981867

Microcystin-LR induced microfilament rearrangement and cell invasion by activating ERK/VASP/ezrin pathway in DU145 cells. PMID: 35248587

Epitopes prediction for microcystin-LR by molecular docking. PMID: 34717216

Behavior and fate of microcystin-LR in soils amended with biochar and peat. PMID: 35961568

Microcystin-LR and okadaic acid-induced cellular effects: a dualistic response. PMID: 14741332

Using soil amendments to reduce microcystin-LR bioaccumulation in lettuce. PMID: 34648839

Tumor promoters--microcystin-LR, nodularin and TNF-α and human cancer development. PMID: 21269254

The role of PP2A-associated proteins and signal pathways in microcystin-LR toxicity. PMID: 25922137

Atmospheric chemical processes of microcystin-LR at the interface of sea spray aerosol. PMID: 35085608

Effects of microcystin-LR and cylindrospermopsin on plant-soil systems: A review of their relevance for agricultural plant quality and public health. PMID: 27702441

Microcystin-LR exposure disrupts the insulin signaling pathway in C2C12 mice muscle cell line. PMID: 31714646

The toxicology of microcystin-LR: occurrence, toxicokinetics, toxicodynamics, diagnosis and treatment. PMID: 11577938

First Report on Microcystin-LR Occurrence in Water Reservoirs of Eastern Cuba, and Environmental Trigger Factors. PMID: 35324706

Excluding interference and detecting Microcystin-LR in the natural lakes and cells based a unique fluorescence method. PMID: 35810636

Microcystin-LR degradation kinetics during chlorination: Role of water quality conditions. PMID: 32823198

Ultrasensitive Aptasensor for Microcystin-LR Detection in Food Samples Based on Target-Activated Assembly of Y-Shaped Hairpin Probes. PMID: 36524375

Qualitative and quantitative detection of microcystin-LR based on SERS-FET dual-mode biosensor. PMID: 35671700

Genotoxicity of microcystin-LR in mammalian cells: Implication from peroxynitrite produced by mitochondria. PMID: 32179236

The monthly variation tendency of microcystin-LR levels in the Huangpu River (China) by applications of ELISA and HPLC. PMID: 35347625

Rapid detoxification of Microcystin-LR by selective catalytic hydrogenation of the Adda moiety using TiO2-supported Pd catalysts. PMID: 34687684

Subacute and sublethal ingestion of microcystin-LR impairs lung mitochondrial function by an oligomycin-like effect. PMID: 35598755

Photodegradation of microcystin-LR by pyridyl iron porphyrin immobilized on NaY zeolite. PMID: 32293595

Microcystin-LR, a cyanobacterial toxin affects root development by changing levels of PIN proteins and auxin response in Arabidopsis roots. PMID: 34088085

Microcystin-LR Enrichment from Freshwater by a Recombinant Plant-derived Antibody Using Sol-Gel-Glass Immunoextraction. PMID: 30318489

Degradation of cyanotoxin microcystin-LR in synthetic and natural waters by chemical-free UV/VUV radiation. PMID: 31374374

Adsorption and regeneration on iron-activated biochar for removal of microcystin-LR. PMID: 33497982

Evaluating the microcystin-LR-degrading potential of bacteria growing in extreme and polluted environments. PMID: 37129688

Microcystin-LR induces anoikis resistance to the hepatocyte uptake transporter OATP1B3-expressing cell lines. PMID: 25456266

Microcystin-LR stabilizes c-myc protein by inhibiting protein phosphatase 2A in HEK293 cells. PMID: 24607848

Microcystin-LR promotes epithelial-mesenchymal transition in colorectal cancer cells through PI3-K/AKT and SMAD2. PMID: 27856280

Microcystin-LR disrupts insulin signaling by hyperphosphorylating insulin receptor substrate 1 and glycogen synthase. PMID: 28984034

Removal of microcystin-LR and microcystin-RR by graphene oxide: adsorption and kinetic experiments. PMID: 23764611

Microcystin-LR regulates circadian clock and antioxidant gene expression in cultured rat cardiomyocytes. PMID: 30337942

Removal of microcystin-LR from aqueous solution using Moringa oleifera Lam. seeds. PMID: 30816867

Microcystin-LR induces autophagy and apoptosis in rat Sertoli cells in vitro. PMID: 24047964

Microcystin-LR exposure induced nephrotoxicity by triggering apoptosis in female zebrafish. PMID: 30290360

Microcystin-LR and chemically degraded microcystin-LR electrochemical oxidation. PMID: 22377975

Ultrasensitive detection of microcystin-LR with gold immunochromatographic assay assisted by a molecular imprinting technique. PMID: 30722906

Understanding microcystin-LR antibody binding interactions using in silico docking and in vitro mutagenesis. PMID: 32725153

Combined toxic effects of anatoxin-a and microcystin-LR on submerged macrophytes and biofilms. PMID: 31978825

Photodegradation of microcystin-LR using graphene-TiO2/sodium alginate aerogels. PMID: 30143110

Microcystin-LR induces protein phosphatase 2A alteration in a human liver cell line. PMID: 23436320

Occurrence of microcystin-LR in vegetated lagoons used for urban runoff management. PMID: 30772435

Electrochemical degradation of microcystin-LR. PMID: 15717787

The differential effects of microcystin-LR on mitochondrial DNA in the hippocampus and cerebral cortex. PMID: 29729571

Microcystin (-LR) affects hormones level of male mice by damaging hypothalamic-pituitary system. PMID: 22178782

Selective and easy detection of microcystin-LR in freshwater using a bioactivated sensor based on multiwalled carbon nanotubes on filter paper. PMID: 34325323

Anaerobic degradation of microcystin-LR by an indigenous bacterial Enterobacter sp. YF3. PMID: 31818227

Microcystin-LR causes cytotoxicity effects in rat testicular Sertoli cells. PMID: 22301162

Adsorption of microcystin-LR onto kaolinite, illite and montmorillonite. PMID: 30611067

Microcystin-LR sorption and desorption by diverse biochars: Capabilities, and elucidating mechanisms from novel insights of sorption domains and site energy distribution. PMID: 32916485

Effect of microcystin-LR on human placental villous trophoblast differentiation in vitro. PMID: 25346179

Ultrasensitive photoelectrochemical microcystin-LR immunosensor using carboxyl-functionalized graphene oxide enhanced gold nanoclusters for signal amplification. PMID: 34711309

A novel SERS-based aptasensor for ultrasensitive sensing of microcystin-LR. PMID: 30583362

Microcystin-LR in Brazilian aquaculture production systems. PMID: 20369568

Microcystin-LR does not induce alterations to transcriptomic or metabolomic profiles of a model heterotrophic bacterium. PMID: 29240841

Structural basis of microcystinase activity for biodegrading microcystin-LR. PMID: 31310980

Antioxidant Activity of Silymarin in Microcystin-LR Cardiac and Pulmonary Induced Injuries on Mice. PMID: 33274863

An aptamer based fluorometric microcystin-LR assay using DNA strand-based competitive displacement. PMID: 31197617

An examination of microcystin-LR accumulation and toxicity using tethered bilayer lipid membranes (tBLMs). PMID: 30521837

Microcystin-LR promotes melanoma cell invasion and enhances matrix metalloproteinase-2/-9 expression mediated by NF-κB activation. PMID: 22992115

Microcystin-LR-caused ROS generation involved in p38 activation and tau hyperphosphorylation in neuroendocrine (PC12) cells. PMID: 24142891

Microcystin-LR causes sexual hormone disturbance in male rat by targeting gonadotropin-releasing hormone neurons. PMID: 27773737

Investigating the microbial dynamics of microcystin-LR degradation in Lake Erie sand. PMID: 33592515

Aptamer-Target Recognition-Promoted Ratiometric Electrochemical Strategy for Evaluating the Microcystin-LR Residue in Fish without Interferences. PMID: 35012307

Impacts of algal organic matter and humic substances on microcystin-LR removal and their biotransformation during the biodegradation process. PMID: 35964751

Proteasome as a Molecular Target of Microcystin-LR. PMID: 26090622

Microcystin-LR modulates selected immune parameters and induces necrosis/apoptosis of carp leucocytes. PMID: 20821480

Microcystin LR degradation by Pseudomonas aeruginosa alkaline protease. PMID: 9569941

Multiple pathways for the anaerobic biodegradation of microcystin-LR in the enriched microbial communities from Lake Taihu. PMID: 34995687

Safety assessment of graphene oxide and microcystin-LR complex: a toxicological scenario beyond physical mixture. PMID: 35392949

Microcystin-LR reduces the synthesis of gonadotropin-releasing hormone by activating multiple signaling pathways resulting in decrease of testosterone in mice. PMID: 29945085

Electrochemical detection of microcystin-LR based on its deleterious effect on DNA. PMID: 29759219

Thermally enhanced adsorption and persulfate oxidation-driven regeneration on FeCl3-activated biochar for removal of microcystin-LR in water. PMID: 34426274

Light-sheet skew rays enhanced U-shaped fiber-optic fluorescent immunosensor for Microcystin-LR. PMID: 33341317

Separation of Microcystin-LR by Cyclodextrin-Functionalized Magnetic Composite of Colloidal Graphene and Porous Silica. PMID: 25906257

Acute toxic effects of microcystin-LR on crayfish (Procambarus clarkii): Insights from antioxidant system, histopathology and intestinal flora. PMID: 36918491

Distribution of microcystin-LR to testis of male Sprague-Dawley rats. PMID: 24150695

Non-enzymatic portable optical sensors for microcystin-LR. PMID: 29479587

Microcystin-leucine arginine (MC-LR) induces bone loss and impairs bone micro-architecture by modulating host immunity in mice: Implications for bone health. PMID: 29626823

Microcystin-LR degradation by solar photo-Fenton, UV-A/photo-Fenton and UV-C/H2O2: a comparative study. PMID: 23178743

Low-temperature catalytic aqueous phase oxidation of microcystin-LR with iron-doped TiO2 pillared clay catalysts. PMID: 32100642

Exploring the interaction of microcystin-LR with proteins and DNA. PMID: 18675338

The localization of exogenous microcystin LR taken up by a non-microcystin producing cyanobacterium. PMID: 25064273

Microcystin-LR leads to oxidative damage and alterations in antioxidant defense system in liver and gills of Brycon amazonicus (SPIX & AGASSIZ, 1829). PMID: 29024772

Microcystin-LR-induced ultrastructural changes in rats. PMID: 2106745

Allium sativum mitigates oxidative damages induced by Microcystin-LR in heart and liver tissues of mice. PMID: 34217748

Fluorescence Spectra Predict Microcystin-LR and Disinfection Byproduct Formation Potential in Lake Water. PMID: 30561985

Overexpression of carboxylesterase contributes to the attenuation of cyanotoxin microcystin-LR toxicity. PMID: 28163251

Effect of varying pH and co-existing microcystin-LR on time- and concentration-dependent cadmium sorption by goethite-modified biochar derived from distillers' grains. PMID: 35595000

Cell density-dependent regulation of microcystin synthetase genes (mcy) expression and microcystin-LR production in Microcystis aeruginosa that mimics quorum sensing. PMID: 34020285

Mechanism for the Potential Inhibition Effect of Microcystin-LR Disinfectant By-Products on Protein Phosphatase 2A. PMID: 36548775

A novel CRISPR/Cas14a system integrated with 2D porphyrin metal-organic framework for microcystin-LR determination through a homogeneous competitive reaction. PMID: 34799170

Ozonation degradation of microcystin-LR in aqueous solution: intermediates, byproducts and pathways. PMID: 24981743

Optimization on preparation of Fe3O4/chitosan as potential matrix material for the removal of microcystin-LR and its evaluation of adsorption properties. PMID: 31805328

Characterization of microcystin-LR removal process in the presence of probiotic bacteria. PMID: 22115989

Comprehensive proteomic and phosphoproteomic reveal that Microcystin-LR contributed to the malignant progression of gastric cancer by estrogenic potency. PMID: 36436660

Effect of Microcystis aeruginosa-Associated Microcystin-LR on the Survival of 2 Life Stages of Freshwater Mussel (Lampsilis siliquoidea). PMID: 31233235

Effects of arginine on the growth and microcystin-LR production of Microcystis aeruginosa in culture. PMID: 30245426

Detoxification of microcystin-LR in water by Portulaca oleracea cv. PMID: 23999063

P44/42 MAPK signal pathway-mediated hyperphosphorylation of paxillin and redistribution of E-cadherin was involved in microcystin-LR-reduced cellular adhesion in a human liver cell line. PMID: 29505932

Microcystin-LR inhibited hippocampal long-term potential via regulation of the glycogen synthase kinase-3β pathway. PMID: 23701903

Datasheet
$ 372
Product specifications
100 μg 372 1 mg 1860

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Anti-Microcystin-LR/RR Antibody (MC10E7) [RGN10001]
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