Catalog No.
YMJ48301
Expression system
E. coli
Species
Mus musculus (Mouse)
Protein length
Gly203-Ala303
Predicted molecular weight
23.47 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9Z0J7
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Mic1, GDF-15, Sbf, Growth/differentiation factor 15, Macrophage inhibitory cytokine 1, Gdf15, MIC-1
Omaveloxolone, But Not Dimethyl Fumarate, Improves Cardiac Function in Friedreich's Ataxia Mice With Severe Cardiomyopathy., PMID:40501183
Associations between physical activity and CVD-related metabolomic and proteomic biomarkers., PMID:40498722
Inflammatory and vascular biomarkers as predictors of all-cause death and cardiovascular outcomes in an Australian community-based cohort., PMID:40495286
The AMPK/GDF15 Axis: A Novel Target for the Neuroprotective Effects of Metformin in Ischemic Stroke., PMID:40489027
In-silico identification and experimental validation of shared genes and pathways to decipher the molecular links between COPD and MASLD., PMID:40482557
Serum growth differentiation factor 15 associates with extra-glandular manifestations and disease activity of primary Sjögren's syndrome., PMID:40481066
The relationship between inflammatory factors and major adverse cardiovascular events in atherosclerosis coronary artery ectasia: a prospective, cohort study., PMID:40476575
Bone, dentin and cementum differentially influence the differentiation of osteoclast-like cells., PMID:40473827
Growth Differentiation Factor 15 Induces Gastric Fundus Contraction Involving Cholinergic Excitation: Morphofunctional Evidence in Rodent Models., PMID:40464681
Role of GDF-15 and NRG-1 as predictive markers of coronary artery disease., PMID:40459638
MACanalyzeR scRNAseq analysis tool reveals PPARγHIGH/GDF15HIGH lipid-associated macrophages facilitate thermogenic expansion in BAT., PMID:40450001
Brain-acting hepatokines: its impact on energy balance and metabolism., PMID:40443802
Biomarkers of Calcification, Endothelial Injury, and Platelet-Endothelial Interaction in Patients with Aortic Valve Stenosis., PMID:40430015
[A comprehensive study of Alzheimer's disease biomarkers in plasma and cerebrospinal fluid]., PMID:40420450
Super-resolution imaging informed scRNA sequencing analysis reveals the critical role of GDF15 in rejuvenating aged hematopoietic stem cells., PMID:40416726
GDF15 suppresses abdominal aortic aneurysm by upregulating AREG expression to adjust macrophage polarization., PMID:40414071
Effects of exercise conducted prior to phenylketonuria-type meal on appetite, satiety hormones and energy expenditure: a randomised cross-over trial., PMID:40410377
Characterization of feline nonsteroidal anti-inflammatory drug activated gene-1 (fNAG-1) and its protective function in kidney cells., PMID:40399974
Desensitizing Effect of Intra-Tumoral GDF-15 on Immunotherapy in Patients With Advanced Non-Small Cell Lung Cancer., PMID:40396532
Interplay between sarcopenia, GDF-15, and the efficacy of nivolumab plus ipilimumab in patients with mismatch repair deficient metastatic colorectal cancer: final survival analysis of the phase II GERCOR NIPICOL study., PMID:40389373
Damnacanthal exerts anti-cancer effects in breast cancer cells via NAG-1 upregulation, CRM1 downregulation, and induction of autophagy., PMID:40381674
Hepatic estrogen-related receptor gamma is a key regulator of GDF15 production in acute and chronic liver injury., PMID:40379080
Age-Associated Increase in Growth Differentiation Factor 15 Levels Correlates With Central Arterial Stiffness and Predicts All-Cause Mortality in a Sardinian Population Cohort., PMID:40371596
Diagnostic and Prognostic Evaluation of Novel Biomarkers Compared to ESC 0/1 h and 0/3 h Algorithms in Patients with Suspected Non-ST-Elevation Myocardial Infarction., PMID:40363990
Macrophage Depletion Alleviates Immunosenescence in Diabetic Kidney by Modulating GDF-15 and Klotho., PMID:40362229
The Potential of Cardiac Biomarkers in Differentiating Disease Subtypes in Patients with Systemic Sclerosis: Focus on GDF15, MR-pro ANP, and suPAR., PMID:40362179
Randomized Phase II Study of Nab-Paclitaxel and Gemcitabine With or Without Tocilizumab as First-Line Treatment in Advanced Pancreatic Cancer: Survival and Cachexia., PMID:40354592
First-in-Human Study to Evaluate the Safety and Efficacy of Anti-GDF15 Antibody AZD8853 in Patients with Advanced/Metastatic Solid Tumors., PMID:40354065
Biomarkers of oxidative and mitochondrial stress are associated with accelerated pace of aging at midlife in a birth cohort., PMID:40341365
Dual-responsive nanoparticles targeting ACE-II senescence for therapeutic mitigation of acute lung injury., PMID:40340852
ADORE: an open platform study of ruxolitinib in combination with other novel therapies in patients with myelofibrosis., PMID:40334082
Verbascoside attenuates myocardial ischemia/reperfusion-induced ferroptosis following heterotopic heart transplantation via modulating GDF15/GPX4/SLC7A11 pathway., PMID:40325032
Circulating and hepatic levels of growth differentiation factor 15 in patients with metabolic dysfunction-associated steatotic liver disease., PMID:40317579
Social isolation, loneliness and the relationship with serum biomarkers, functional parameters and mortality in older adults., PMID:40317389
NAG-1/GDF15 as a tumor suppressor in colorectal cancer: inhibition of β-catenin and NF-κB pathways via interaction with EpCAM., PMID:40316530
The plasma proteome is linked to echocardiographic parameters and stages of diastolic dysfunction, across the ejection fraction spectrum., PMID:40311691
Revisiting the role of GDF15 in atherosclerosis in mouse and human., PMID:40307459
Growth differentiation factor 15: a promising biomarker in oral cancer., PMID:40296737
Decipher the single-cell level responses to chemotherapy in pancreatic ductal adenocarcinoma by a cross-time context graph model., PMID:40294840
Beyond a Single Marker: An Update on the Comprehensive Evaluation of Right Ventricular Dysfunction in Pulmonary Thromboembolism., PMID:40283221
GDF15 drives de novo lipogenesis and contributes to ovarian cancer metastasis., PMID:40280199
Biology of RET receptor and its ligands: focus on the nervous system., PMID:40272927
Longitudinal changes in blood-borne geroscience biomarkers: results from a population-based study., PMID:40272732
The association between serum growth differentiation factor 15 and insulin resistance in women diagnosed with polycystic ovary syndrome., PMID:40263510
1000-plex antibody array proteomic screen uncovers PGRPS, Haptoglobin, Serpin A4 and Fibrinogen as potential stool biomarkers of pediatric inflammatory bowel disease., PMID:40252987
The composition of single-donor apheresis platelet concentrates is influenced by the age of the donor., PMID:40251396
Chemical Affinity Capture of Plasma Extracellular Vesicles Enables Efficient and Large-Scale Proteomic Identification of Prostate Cancer Biomarkers., PMID:40248970
Cardiovascular Biomarkers: Tools for Precision Diagnosis and Prognosis., PMID:40244022
GDF15 links adipose tissue lipolysis with anxiety., PMID:40234625
Biomarker and cognitive decline in atrial fibrillation: a prospective cohort study., PMID:40234472
For research use only. Not for human or drug use.
