Catalog No.
YHE58501
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ser2-Ser62
Predicted molecular weight
19.00 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P48539
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
PCP4, Calmodulin regulator protein PCP4, Purkinje cell protein 4, Brain-specific polypeptide PEP-19, PEP19
Deep learning analyses of splicing variants identify the link of PCP4 with amyotrophic lateral sclerosis., PMID:39852553
Number of subfields of the rat dorsal subiculum defined by NOS and PCP4 immunoreactivity changes according to different levels of observation., PMID:39755232
Heat Stress Induces Alterations in Gene Expression of Actin Cytoskeleton and Filament of Cellular Components Causing Gut Disruption in Growing-Finishing Pigs., PMID:39272260
CAMK2G Promotes Neuronal Differentiation and Inhibits Migration in Neuroblastoma., PMID:39266386
Proteomic changes in the hippocampus of large mammals after total-body low dose radiation., PMID:38427613
Identification of hippocampal area CA2 in hamster and vole brain., PMID:38405991
Immunohistochemical field parcellation of the human hippocampus along its antero-posterior axis., PMID:38180568
The epithelial transcriptome and mucosal microbiota are altered for goats fed with a low-protein diet., PMID:37731924
Screening and validation of plasma cell-derived, purinergic, and calcium signalling-related genetic signature to predict prognosis and PD-L1/PD-1 blockade responses in lung adenocarcinoma., PMID:37468608
PCP4 Promotes Alzheimer's Disease Pathogenesis by Affecting Amyloid-β Protein Precursor Processing., PMID:37302034
Defining hippocampal area CA2 in the fox (Vulpes vulpes) brain., PMID:37159095
Characteristic Analysis of Featured Genes Associated with Cholangiocarcinoma Progression., PMID:36979826
Morphological and molecular markers of mouse area CA2 along the proximodistal and dorsoventral hippocampal axes., PMID:36762588
Molecular Mechanism of Long Noncoding RNA SNHG14 in Osteogenic Differentiation of Bone Marrow-Derived Mesenchymal Stem Cells through the NEDD4L/FOXA2/PCP4 Axis., PMID:36644009
Exercise mitigates calpain induced Purkinje cell loss in diabetes., PMID:36150460
Estrogen differentially regulates transcriptional landscapes of preoptic and arcuate kisspeptin neuron populations., PMID:36093104
Pep19 Has a Positive Effect on Insulin Sensitivity and Ameliorates Both Hepatic and Adipose Tissue Phenotype of Diet-Induced Obese Mice., PMID:35456900
Circ_0019693 promotes osteogenic differentiation of bone marrow mesenchymal stem cell and enhances osteogenesis-coupled angiogenesis via regulating microRNA-942-5p-targeted purkinje cell protein 4 in the development of osteoporosis., PMID:35030971
PCP4/PEP19 and HER2 Are Novel Prognostic Markers in Mucoepidermoid Carcinoma of the Salivary Gland., PMID:35008217
Laminar Organization of the Entorhinal Cortex in Macaque Monkeys Based on Cell-Type-Specific Markers and Connectivity., PMID:34949991
The Bioinformatics Analysis of Aldosterone-Producing Adenoma and Verification of Differentially Expressed Genes., PMID:34675975
Evaluation of CD109, PCP4 and SEMA3D genes for their association with Ovine Johne's disease in Turkish sheep., PMID:33612073
Postnatal Developmental Expression Profile Classifies the Indusium Griseum as a Distinct Subfield of the Hippocampal Formation., PMID:33511122
Exercise-mitigated sex-based differences in aging: from genetic alterations to heart performance., PMID:33337964
GNG13 Is a Potential Marker of the State of Health of Alzheimer's Disease Patients' Cerebellum., PMID:33057964
PCP4/PEP19 downregulates neurite outgrowth via transcriptional regulation of Ascl1 and NeuroD1 expression in human neuroblastoma M17 cells., PMID:32641824
Runx2 Regulates Mouse Tooth Root Development Via Activation of WNT Inhibitor NOTUM., PMID:32569388
miR-122 Exerts Inhibitory Effects on Osteoblast Proliferation/Differentiation in Osteoporosis by Activating the PCP4-Mediated JNK Pathway., PMID:32199130
Airway Ciliary Beating Affected by the Pcp4 Dose-Dependent [Ca2+]i Increase in Down Syndrome Mice, Ts1Rhr., PMID:32178446
Peptides from Natural or Rationally Designed Sources Can Be Used in Overweight, Obesity, and Type 2 Diabetes Therapies., PMID:32121443
Overexpression of human wtTDP-43 causes impairment in hippocampal plasticity and behavioral deficits in CAMKII-tTa transgenic mouse model., PMID:31705957
Antimicrobial peptides Pep19-2.5 and Pep19-4LF inhibit Streptococcus mutans growth and biofilm formation., PMID:31112769
Transcriptomic profile of the subiculum-projecting VIP GABAergic neurons in the mouse CA1 hippocampus., PMID:31098764
Internal structure of the rat subiculum characterized by diverse immunoreactivities and septotemporal differences., PMID:30768950
Expression, Regulation, and Function of the Calmodulin Accessory Protein PCP4/PEP-19 in Myometrium., PMID:30744532
PCP4/PEP19 upregulates aromatase gene expression via CYP19A1 promoter I.1 in human breast cancer SK-BR-3 cells., PMID:30038708
Upregulation of PCP4 in human aldosterone-producing adenomas fosters human adrenocortical tumor cell growth via AKT and AMPK pathway., PMID:31938214
Purkinje Cell Protein 4 Expression Is Associated With DNA Methylation Status in Aldosterone-Producing Adenoma., PMID:29294065
New insights into the gene expression associated to amyotrophic lateral sclerosis., PMID:29241710
Microarray analysis of copy-number variations and gene expression profiles in prostate cancer., PMID:28700469
Gene networks in neurodegenerative disorders., PMID:28623007
Antisense oligonucleotide therapy for spinocerebellar ataxia type 2., PMID:28405024
Brain ventriculomegaly in Down syndrome mice is caused by Pcp4 dose-dependent cilia dysfunction., PMID:28069794
PEP-19 modulates calcium binding to calmodulin by electrostatic steering., PMID:27876793
Prognostic gene expression profiling in esophageal cancer: a systematic review., PMID:27852047
Immunohistochemical investigation of the internal structure of the mouse subiculum., PMID:27664459
MS imaging and mass spectrometric synaptosome profiling identify PEP-19/pcp4 as a synaptic molecule involved in spatial learning in mice., PMID:27760390
Peptide 19 of Porphyromonas gingivalis Heat Shock Protein Is a Potent Inducer of Low-Density Lipoprotein Oxidation., PMID:27712463
A Systems View of the Differences between APOE ε4 Carriers and Non-carriers in Alzheimer's Disease., PMID:27462267
PCP4/PEP19 promotes migration, invasion and adhesion in human breast cancer MCF-7 and T47D cells., PMID:27384474
For research use only. Not for human or drug use.
