The m6A and immune regulatory gene signature predicts the prognosis and correlates with immune infiltration of head and neck squamous cell carcinoma., PMID:39524706
Interleukin-11 signaling plays limited roles for liver fibrosis in a mouse model of metabolic dysfunction-associated steatohepatitis., PMID:39536410
Effects of intranasal administration with a symbiotic strain of Bacillus velezensis NSV2 on nasal cavity mucosal barrier in lambs., PMID:39565462
Expression profiling of antimicrobial peptides and immune-related genes in Nile tilapia following Pseudomonas putida infection and nano-titanium dioxide gel exposure., PMID:39577786
Ershen Zhenwu Decoction suppresses myocardial fibrosis of chronic heart failure with heart-kidney Yang deficiency by down-regulating the Ras Homolog Gene Family Member A/Rho-Associated Coiled-Coil Kinases signaling pathway., PMID:39580131
Integrated Transcriptome Profiling and Pan-Cancer Analyses Reveal Oncogenic Networks and Tumor-Immune Modulatory Roles for FABP7 in Brain Cancers., PMID:39596296
The dichotomic role of cytokines in aging., PMID:39621124
Breast cancer stem cell-derived exosomal lnc-PDGFD induces fibroblast-niche formation and promotes lung metastasis., PMID:39633064
Prevent and Reverse Metabolic Dysfunction-Associated Steatohepatitis and Hepatic Fibrosis via mRNA-Mediated Liver-Specific Antibody Therapy., PMID:39639502
Study of Neuroinflammation in the Rat Hippocampus during Ethanol Exposure and Pharmacological Correction with Azithromycin: New Data and Future Perspectives., PMID:39647820
More and more pleiotropy within the IL-6 family of cytokines., PMID:39673075
Higher Intraocular Levels of Inflammatory Factors are Related to Retinal Vascular and Neurodegeneration in Myopic Retinopathy., PMID:39677296
Potential Biomarkers in Myocardial Fibrosis: A Bioinformatic Analysis., PMID:39699450
Didecyldimethylammonium chloride-induced lung fibrosis may be associated with phospholipidosis., PMID:39710153
De novo discovery of cyclic peptide inhibitors of IL-11 signaling., PMID:39756345
Single cell and spatial analysis of immune-hot and immune-cold tumours identifies fibroblast subtypes associated with distinct immunological niches and positive immunotherapy response., PMID:39757146
Bone Marrow Mesenchymal Stem Cells Ameliorate Diabetes and Diabetic Renal Fibrosis by Modulating the Inflammatory Factor IL-11., PMID:39757600
Pharmacokinetic and Metabolomic Studies with BBT-059 in Nonhuman Primates Exposed to Total-Body Gamma Radiation., PMID:39786949
Inhalable siRNA Targeting IL-11 Nanoparticles Significantly Inhibit Bleomycin-Induced Pulmonary Fibrosis., PMID:39791575
Decreased expression of LEF1 caused defective decidualization by inhibiting IL-11 expression in patients with adenomyosis., PMID:39794729
Sinensetin attenuates LPS-induced acute pulmonary inflammation in mice and RAW264.7 cells by modulating NF-κB p65-mediated immune resistance and STAT3-mediated tissue resilience., PMID:39827664
Role of Adenosine A1 Receptor in Sleep Deprivation-Induced Neuroinflammation: Insights on Rapid Eye Movement Sleep and Fear Extinction Memory Recall in Rats., PMID:39830563
Long-term increase in soluble interleukin-6 receptor levels in convalescents after mild COVID-19 infection., PMID:39835136
Exploring the therapeutic effect of human recombinant IL11 on lesioned OA human osteochondral explants., PMID:39856704
Transforming growth factor beta induces interleukin-11 expression in osteoarthritis., PMID:39879889
Potential benefits of ketone therapy as a novel immunometabolic treatment for schizophrenia., PMID:39892306
TME-responsive nanocomposite hydrogel with targeted capacity for enhanced synergistic chemoimmunotherapy of MYC-amplified osteosarcoma., PMID:39897587
Edaravone dexborneol alleviates pericyte-mediated fibrosis depositing extracellular matrix through TGF-β1/IL-11 in cerebral small vessel disease., PMID:39910578
Site-specific immunoglobulin G N-glycosylation is associated with gastric cancer progression., PMID:39920693
Comparative analysis of salivary cytokine profiles and oral microbial composition in caries-active and caries-free children., PMID:39921084
Spatial proteomics identifies a CRTC-dependent viral signaling pathway that stimulates production of interleukin-11., PMID:39921859
IL-11 regulates the biosynthesis of PGE2 through JAK1/STAT3 signaling pathway in bovine granulosa cells., PMID:39986217
Biofunctionalization of Collagen Barrier Membranes with Bone-Conditioned Medium, as a Natural Source of Growth Factors, Enhances Osteoblastic Cell Behavior., PMID:40004074
PDK2-enhanced glycolysis aggravates fibrosis via IL11 signaling pathway in Graves' orbitopathy., PMID:40018034
Exploring immunological and molecular mechanisms involved in obsessive-compulsive disorder with comorbid neurodevelopmental disorders., PMID:40036942
Interleukin-11 expressed in the polyp-enriched fibroblast subset is a potential therapeutic target in Peutz-Jeghers syndrome., PMID:40070038
IL-11 promotes Ang II-induced autophagy inhibition and mitochondrial dysfunction in atrial fibroblasts., PMID:40092733
Biomarkers of the Complement System in Cancer., PMID:40152065
The signature based on interleukin family and receptors identified IL19 and IL20RA in promoting nephroblastoma progression through STAT3 pathway., PMID:40185911
Sodium propionate protects against bronchopulmonary dysplasia by inhibiting IL-17-mediated apoptosis of alveolar epithelial cells., PMID:40188136
Development of a Long-Acting Interleukin-11 Antagonist for the Treatment of Renal Fibrosis., PMID:40198895
Toxic effects and transcriptome analysis of the early life stages of Larimichthys crocea exposed to the bloom-forming dinoflagellate Alexandrium tamarense., PMID:40252594
Therapeutic effect of nintedanib in orbital fibroblasts in patients with Graves' orbitopathy., PMID:40289264
COVID-19 mRNA-1273 vaccination induced mast cell activation with strongly elevated Th2 cytokines in a systemic mastocytosis patient., PMID:40299000
Inhalable myofibroblast targeting nanoparticles for synergistic treatment of pulmonary fibrosis., PMID:40305619
"Maladaptive stress-coping behavior in CX3CR1-deficient mice: Impact of adolescent stress and alcohol exposure on neuroimmune responses and inflammation"., PMID:40339639
[Shenge powder inhibits myocardial fibrosis in rats with post-myocardial infarction heart failure through LOXL2/TGF-β1/IL-11 signaling pathway]., PMID:40342293
Genetic Insights Into Craniosynostosis: Identification of Novel IL11RA Variants in Chinese Pediatric Patients., PMID:40353334
Combined Oral Contraceptives Modulate Apoptosis via IL-11/PI3K/AKT Pathway in Rat With Premature Ovarian Insufficiency., PMID:40485524
Prognostic significance of IL11RA and its methylation in lung adenocarcinoma., PMID:40530134
Interleukin-11 classic but not trans-signaling is essential for fertility in mice. PMID: 28864002
[Interleukin-11, 12, 13, 14, 15, 16, 17, 18 (IL-11, 12, 13, 14, 15, 16, 17, 18)]. PMID: 16149457
Preclinical pharmacologic basis for clinical use of rhIL-11 as an effective platelet-support agent. PMID: 11033834
Interleukin (IL)-11--mediated signal transduction. PMID: 7545369
IL-11 system participates in pulmonary artery remodeling and hypertension in pulmonary fibrosis. PMID: 36376885
[International therapeutics]. PMID: 14974887
Preclinical biology of interleukin 11: a multifunctional hematopoietic cytokine with potent thrombopoietic activity. PMID: 8528095
The clinical development of recombinant human interleukin 11 (NEUMEGA rhIL-11 growth factor). PMID: 11012229
Complex pattern of interleukin-11-induced inflammation revealed by mathematically modeling the dynamics of C-reactive protein. PMID: 25231819
miR-10396b-3p inhibits mechanical stress-induced ligamentum flavum hypertrophy by targeting IL-11. PMID: 34042220
A polymorphic dinucleotide repeat in the 5' flanking region of the human interleukin 11 (IL11) gene. PMID: 9553159
Estrogen receptor variant ERα46 and insulin receptor drive in primary breast cancer cells growth effects and interleukin 11 induction prompting the motility of cancer-associated fibroblasts. PMID: 34841688
Decreased interleukin-11 levels in the semen of infertile males. PMID: 29573586
The interleukin-11/receptor complex: rational design of agonists/antagonists and immunoassays potentially useful in human therapy. PMID: 9851534
Interleukin 11 treatment alters the protein content of Galpha(i2) and adipogenic transcription factors in 3T3-L1 adipocytes. PMID: 15207245
Thrombopoietic activity of recombinant human interleukin 11 in cancer patients receiving chemotherapy. PMID: 8765426
The cloning and biological characterization of recombinant human interleukin 11. PMID: 1535352
Review of a novel hematopoietic cytokine, interleukin-11. PMID: 8454414
Effect of interleukin 11 on normal and pathological thrombopoiesis. PMID: 8765427
CD39+ Fibroblasts Enhance Myofibroblast Activation by Promoting IL-11 Secretion in Hypertrophic Scars. PMID: 34537192
MEK/ERK/RUNX2 Pathway-Mediated IL-11 Autocrine Promotes the Activation of Müller Glial Cells during Diabetic Retinopathy. PMID: 36154781
Interleukin-11 is important for vascular smooth muscle phenotypic switching and aortic inflammation, fibrosis and remodeling in mouse models. PMID: 33082445
Use of thrombopoietic growth factors in acute leukemia. PMID: 10720151
Biologic and structural differences of thrombopoietic growth factors. PMID: 10831285
[Function, molecular structure and gene expression of interleukin-11 (IL-11/AGIF)]. PMID: 1433976
Mutational Analysis of Interleukin-11 and its Consequences on Cancer and COVID-19 Related Cytokine Storm -An Extensive Molecular Dynamics Study. PMID: 35382714
IL-11: insights in asthma from overexpression transgenic modeling. PMID: 11590369
Interactions between glucocorticoids and cytokines in the bone microenvironment. PMID: 12114264
The role of IL-II in hematopoiesis as revealed by a targeted mutation of its receptor. PMID: 11012177
Interleukin-11: a multifunctional growth factor derived from the hematopoietic microenvironment. PMID: 7512836
Interleukin-11: review of molecular, cell biology, and clinical use. PMID: 9166826
Hematopoietic, immunomodulatory and epithelial effects of interleukin-11. PMID: 10482979
Management of chemotherapy-induced thrombocytopenia: current status of thrombopoietic agents. PMID: 19245931
Expression, Purification, and Characterization of Interleukin-11 Orthologues. PMID: 27916836
Emerging roles for IL-11 signaling in cancer development and progression: Focus on breast cancer. PMID: 26209885
More than a sidekick: the IL-6 family cytokine IL-11 links inflammation to cancer. PMID: 20610798
Understanding the link between the IL-6 cytokine family and pregnancy: implications for future therapeutics. PMID: 21895473
Preeclampsia-related increase of interleukin-11 expression in human decidual cells. PMID: 20668109
Structural Understanding of Interleukin 6 Family Cytokine Signaling and Targeted Therapies: Focus on Interleukin 11. PMID: 32765502
Regulation of osteoblast differentiation by interleukin-11 via AP-1 and Smad signaling. PMID: 21931225
Interleukin-11: its biology and prospects for clinical use. PMID: 10483899
[Interleukin-11, an IL-6 like cytokine]. PMID: 21485496
The expression analysis of Fra-1 gene and IL-11 protein in Iranian patients with ulcerative colitis. PMID: 29914371
Interleukin 11 regulates endometrial cancer cell adhesion and migration via STAT3. PMID: 22614117
Cytokine therapy in rheumatoid arthritis. PMID: 9836382
Critical Conditions for Studying Interleukin-11 Signaling In Vitro and Avoiding Experimental Artefacts. PMID: 34570432
Regulation of interleukin-11 expression in ovulatory follicles of the rat ovary. PMID: 28521851
Generation of Soluble Interleukin-11 and Interleukin-6 Receptors: A Crucial Function for Proteases during Inflammation. PMID: 27493449
Human cytomegalovirus replication induces endothelial cell interleukin-11. PMID: 29807687
Interleukin-11 alters placentation and causes preeclampsia features in mice. PMID: 26655736
Cytokine signalling via gp130 in gastric cancer. PMID: 19665497
Interleukin-11: a novel stroma-derived cytokine. PMID: 1307488
Leukemia inhibitory factor and interleukin-11: critical regulators in the establishment of pregnancy. PMID: 19647472
Re-thinking the role of IL-11 in liver injury. PMID: 34183810
Interleukin-11 up-regulates endoplasmic reticulum stress induced target, PDIA4 in human first trimester placenta and in vivo in mice. PMID: 28487027
Inactivation of IL11 signaling causes craniosynostosis, delayed tooth eruption, and supernumerary teeth. PMID: 21741611
Roles of interleukin-11 during acute bacterial pneumonia. PMID: 31415618
Interleukin 11 is upregulated in preeclampsia and leads to inflammation and preeclampsia features in mice. PMID: 29195119
The biology of interleukin 11. PMID: 8401258
Interleukin 11: an overview. PMID: 8111307
Interleukin-11. A gp130 cytokine. PMID: 9917860
Different roles of interleukin 6 and interleukin 11 in the liver: implications for therapy. PMID: 32530750
A panoramic review and in silico analysis of IL-11 structure and function. PMID: 27312790
Generation of and characterization of anti-IL-11 antibodies using newly established Il11-deficient mice. PMID: 30268501
Split2 Protein-Ligation Generates Active IL-6-Type Hyper-Cytokines from Inactive Precursors. PMID: 29136368
The cytokine interleukin-11 crucially links bone formation, remodeling and resorption. PMID: 33940443
Interleukin-11 and its receptor. PMID: 1292471
IL-11 drives postsurgical hepatocellular carcinoma recurrence. PMID: 31402232
Toward development of interleukin-11 as a medical countermeasure for use in radiological/nuclear emergencies. PMID: 24591015
Interleukin-6 and interleukin-11: same same but different. PMID: 23740659
IL-11 signaling as a therapeutic target for cancer. PMID: 25917632
Interleukin-11: A Multifunctional Cytokine with Intrinsically Disordered Regions. PMID: 27334537
High-affinity interaction between interleukin-11 and S100P protein. PMID: 26551460
The pro-regenerative effects of hyperIL6 in drug-induced liver injury are unexpectedly due to competitive inhibition of IL11 signaling. PMID: 34435951
Interleukin-11: A Potential Biomarker and Molecular Therapeutic Target in Non-Small Cell Lung Cancer. PMID: 35883698
Targeting IL-11 signaling in colon cancer. PMID: 24163267
[fosB/IL-11]. PMID: 15035097
Therapeutic Targeting of IL-11 for Chronic Lung Disease. PMID: 33612289
[Interleukin-11 in Pathologies of the Nervous System]. PMID: 36976735
[The role of interleukin-11 in osteosarcoma]. PMID: 32078699
The role of IL-11 in immunity and cancer. PMID: 26826523
Monomeric state of S100P protein: Experimental and molecular dynamics study. PMID: 31103949
Interleukin 11 is upregulated in uterine lavage and endometrial cancer cells in women with endometrial carcinoma. PMID: 20553623
Oprelvekin. Genetics Institute. PMID: 11890354
Interleukin (IL)11 mediates protein secretion and modification in human extravillous trophoblasts. PMID: 21840908
Antibody-mediated neutralization of IL11 signalling reduces ERK activation and cardiac fibrosis in a mouse model of severe pressure overload. PMID: 33462828
IL-11 in multiple sclerosis. PMID: 26452137
The role of proteolysis in interleukin-11 signaling. PMID: 34624437
Fibroblast-specific IL11 signaling drives chronic inflammation in murine fibrotic lung disease. PMID: 32656894
Interleukin 11. PMID: 7950912
Emerging roles for Interleukin-11 in disease. PMID: 31161823
Review: LIF and IL11 in trophoblast-endometrial interactions during the establishment of pregnancy. PMID: 20129664
IL11: A Specific Repressor of Tumor-Specific CD4+ T Cells. PMID: 34021007
Hepatocyte Specific gp130 Signalling Underlies APAP Induced Liver Injury. PMID: 35806094
Oxygen-Glucose Deprivation Promoted Fibroblast Senescence and Collagen Expression via IL11. PMID: 36292942
Interleukin-11. PMID: 7532057
Hepatectomy promotes recurrence of liver cancer by enhancing IL-11-STAT3 signaling. PMID: 31375423
Osteoblast/osteocyte-derived interleukin-11 regulates osteogenesis and systemic adipogenesis. PMID: 36424386
Emerging roles for IL-11 in inflammatory diseases. PMID: 34689057
Interleukin-11 treatment protected against cerebral ischemia/reperfusion injury. PMID: 31096144
Targeting endogenous kidney regeneration using anti-IL11 therapy in acute and chronic models of kidney disease. PMID: 36470928
IL-11 is a crucial determinant of cardiovascular fibrosis. PMID: 29160304
IL11 Stimulates IL33 Expression and Proinflammatory Fibroblast Activation across Tissues. PMID: 36012165
Inhaled siRNA nanoparticles targeting IL11 inhibit lung fibrosis and improve pulmonary function post-bleomycin challenge. PMID: 35731866
For research use only. Not for human or drug use.
