Pan-cancer analysis supports MAPK12 as a potential prognostic and immunotherapeutic target in multiple tumor types, including in THCA. PMID: 36420075
miR-187 inhibits tumor growth and invasion by directly targeting MAPK12 in osteosarcoma. PMID: 28810556
P38 kinase in gastrointestinal cancers. PMID: 37248432
Loss-of-function RNAi screens in breast cancer cells identify AURKB, PLK1, PIK3R1, MAPK12, PRKD2, and PTK6 as sensitizing targets of rapamycin activity. PMID: 25193464
The Role of p38γ in Cancer: From review to outlook. PMID: 34671218
Initial activation of STAT2 induced by IAV infection is critical for innate antiviral immunity. PMID: 36148221
Oncogenes in melanoma: an update. PMID: 24468268
Inhibiting MAPK14 showed anti-prolactinoma effect. PMID: 32894113
Biology of endothelin receptors in the collecting duct. PMID: 19494799
Cardiac protection by pirfenidone after myocardial infarction: a bioinformatic analysis. PMID: 35304529
Phosphotyrosine profiling of curcumin-induced signaling. PMID: 27307780
Genes Whose Gain or Loss of Function Changes Type 1, 2A, 2X, or 2B Muscle Fibre Proportions in Mice-A Systematic Review. PMID: 36361732
Comprehensive characterization of clonality of driver genes revealing their clinical relevance in colorectal cancer. PMID: 35962343
Machine learning identifies molecular regulators and therapeutics for targeting SARS-CoV2-induced cytokine release. PMID: 34486798
Comparative proteomics reveals genetic mechanisms of body weight in Hu sheep and Dorper sheep. PMID: 35995385
The Dystrophin Glycoprotein Complex Regulates the Epigenetic Activation of Muscle Stem Cell Commitment. PMID: 29681515
Tyrosine Phosphorylation Profiling Revealed the Signaling Network Characteristics of CAMKK2 in Gastric Adenocarcinoma. PMID: 35646067
The role of MAPK11/12/13/14 (p38 MAPK) protein in dopamine agonist-resistant prolactinomas. PMID: 34814904
p38δ MAPK regulates aggresome biogenesis by phosphorylating SQSTM1 in response to proteasomal stress. PMID: 29930081
Dysregulated mitogen-activated protein kinase pathway mediated cell cycle disruption in sporadic parathyroid tumors. PMID: 31535356
DNMT1 and p38γ are inversely expressed in reactive non-metastatic lymph nodes burdened with colorectal adenocarcinoma. PMID: 35847731
Reciprocal allosteric regulation of p38γ and PTPN3 involves a PDZ domain-modulated complex formation. PMID: 25314968
MAP kinase genes and colon and rectal cancer. PMID: 23027623
CXC Chemokines as Therapeutic Targets and Prognostic Biomarkers in Skin Cutaneous Melanoma Microenvironment. PMID: 33767987
p38 MAPK regulates the Wnt inhibitor Dickkopf-1 in osteotropic prostate cancer cells. PMID: 26913608
Promoter DNA hypermethylation and gene repression in undifferentiated Arabidopsis cells. PMID: 18827894
A network-based approach to identify protein kinases critical for regulating srebf1 in lipid deposition causing obesity. PMID: 34327622
Compartmentalizing proximal FGFR1 signaling in ovine placental artery endothelial cell caveolae. PMID: 22674390
Genome-Wide Detection of CNVs and Association With Body Weight in Sheep Based on 600K SNP Arrays. PMID: 32582291
Gene Expression Profiling of the Sciatic Nerve in Streptozotocin-Induced Diabetic Rats with Peripheral Neuropathy. PMID: 32566679
Dual-specificity phosphatase DUSP6 has tumor-promoting properties in human glioblastomas. PMID: 21499306
Two-dimensional phosphate-affinity gel electrophoresis for the analysis of phosphoprotein isotypes. PMID: 19156764
Inhibition of REST Suppresses Proliferation and Migration in Glioblastoma Cells. PMID: 27153061
Evolutionary history of the vertebrate mitogen activated protein kinases family. PMID: 22046431
Regulation of the epithelial Na+ channel by endothelin-1 in rat collecting duct. PMID: 18667482
Microarray study of gene expression in uterine leiomyoma. PMID: 18566572
The role of signaling pathways on proliferation and self-renewal of cultured bovine primitive germ cells. PMID: 29259399
The IDO inhibitor 1-methyl tryptophan activates the aryl hydrocarbon receptor response in mesenchymal stromal cells. PMID: 29190885
The implication from RAS/RAF/ERK signaling pathway increased activation in epirubicin treated triple negative breast cancer. PMID: 29296238
Higher levels of TIMP-1 expression are associated with a poor prognosis in triple-negative breast cancer. PMID: 27130446
Enhanced ABL-inhibitor-induced MAPK-activation in T315I-BCR-ABL-expressing cells: a potential mechanism of altered leukemogenicity. PMID: 22089930
Transcriptomic investigation reveals toxic damage due to tilmicosin and potential resistance against tilmicosin in primary chicken myocardial cells. PMID: 33248551
Biphasic regulation of ENaC by TGF-{alpha} and EGF in renal epithelial cells. PMID: 19297452
A synthetic lethal siRNA screen identifying genes mediating sensitivity to a PARP inhibitor. PMID: 18388863
Role of yes-associated protein 1, angiomotin, and mitogen-activated kinase kinase 1/2 in development of the bovine blastocyst. PMID: 29228123
A robust 11-genes prognostic model can predict overall survival in bladder cancer patients based on five cohorts. PMID: 32843852
Additive Effects of Zinc Chloride on the Suppression of Hepatitis A Virus Replication by Interferon in Human Hepatoma Huh7 Cells. PMID: 33144437
Extended kinase profile and properties of the protein kinase inhibitor nilotinib. PMID: 19922818
Revealing synergistic mechanism of multiple components in Stauntonia brachyanthera Hand.-Mazz. for gout by virtual screening and system pharmacological approach. PMID: 31344517
A functional dynein-microtubule network is required for NGF signaling through the Rap1/MAPK pathway. PMID: 17822405
Aldosterone stimulates proliferation of cardiac fibroblasts by activating Ki-RasA and MAPK1/2 signaling. PMID: 12388314
4-1BB triggers IL-13 production from T cells to limit the polarized, Th1-mediated inflammation. PMID: 17389581
RIPK1 regulates survival of human melanoma cells upon endoplasmic reticulum stress through autophagy. PMID: 26018731
Analysis of miRNA and mRNA reveals core interaction networks and pathways of dexamethasone-induced immunosuppression in chicken bursa of Fabricius. PMID: 33711668
Endothelin-1 induces hypertrophy and inhibits apoptosis in human airway smooth muscle cells. PMID: 16920889
Exposure to ionizing radiation induced persistent gene expression changes in mouse mammary gland. PMID: 23216862
p38γ MAPK Is a Therapeutic Target for Triple-Negative Breast Cancer by Stimulation of Cancer Stem-Like Cell Expansion. PMID: 26077647
Muscle molecular adaptations to endurance exercise training are conditioned by glycogen availability: a proteomics-based analysis in the McArdle mouse model. PMID: 29315579
Targeted degradation of ENaC in response to PKC activation of the ERK1/2 cascade. PMID: 12540365
Modulation of rap activity by direct interaction of Galpha(o) with Rap1 GTPase-activating protein. PMID: 10419452
Differential Expression of the Sphingolipid Pathway Is Associated with Sensitivity to the PP2A Activator FTY720 in Colorectal Cancer Cell Lines. PMID: 34768523
Potential role of sodium-proton exchangers in the low concentration arsenic trioxide-increased intracellular pH and cell proliferation. PMID: 23236503
Gene structure, molecular characterization and transcriptional expression of two p38 isoforms (MAPK11 and MAPK14) from rock bream (Oplegnathus fasciatus). PMID: 26363230
Exploring the cyclooxygenase 2 (COX2)/15d-Δ(12,14)PGJ(2) system in hamster Sertoli cells: regulation by FSH/testosterone and relevance to glucose uptake. PMID: 22974512
Luteolin Targets the Toll-Like Receptor Signaling Pathway in Prevention of Hepatic and Adipocyte Fibrosis and Insulin Resistance in Diet-Induced Obese Mice. PMID: 30282902
Aspirin and alterations in DNA repair proteins in the SW480 colorectal cancer cell line. PMID: 20514442
Systemic anthrax lethal toxin therapy produces regressions of subcutaneous human melanoma tumors in athymic nude mice. PMID: 17189417
Therapeutic metformin/AMPK activation promotes the angiogenic phenotype in the ERalpha negative MDA-MB-435 breast cancer model. PMID: 18256928
Crosstalk between mAChRM3 and β2AR, via acetylcholine PI3/PKC/PBEP1/Raf-1 MEK1/2/ERK1/2 pathway activation, in human bronchial epithelial cells after long-term cigarette smoke exposure. PMID: 29175450
Frequency of actionable alterations in epidermal growth factor receptor (EGFR) wild type non-small cell lung cancer: experience of the Wide Catchment Area of Romagna (AVR). PMID: 30233859
Activation of the MAPK11/12/13/14 (p38 MAPK) pathway regulates the transcription of autophagy genes in response to oxidative stress induced by a novel copper complex in HeLa cells. PMID: 24905917
ROS, Hsp27, and IKKbeta mediate dextran sodium sulfate (DSS) activation of IkappaBa, NFkappaB, and IL-8. PMID: 19085995
Pro-oncogenic role of alternative p38 mitogen-activated protein kinases p38γ and p38δ, linking inflammation and cancer in colitis-associated colon cancer. PMID: 25217523
Monomethyl selenium--specific inhibition of MMP-2 and VEGF expression: implications for angiogenic switch regulation. PMID: 11170262
Ex Vivo Perfusion With Adenosine A2A Receptor Agonist Enhances Rehabilitation of Murine Donor Lungs After Circulatory Death. PMID: 26262504
Diet and lifestyle factors interact with MAPK genes to influence survival: the Breast Cancer Health Disparities Study. PMID: 24993294
Kinin B1 receptor upregulation by angiotensin II and endothelin-1 in rat vascular smooth muscle cells: receptors and mechanisms. PMID: 20833961
miR-200 promotes the mesenchymal to epithelial transition by suppressing multiple members of the Zeb2 and Snail1 transcriptional repressor complexes. PMID: 25798844
[Mitogen-activated protein kinase genes of Artemisia annua and their expression analysis under Cadmium stress]. PMID: 28875663
Early induction of cytokines/cytokine receptors and Cox2, and activation of NF-κB in 4-nitroquinoline 1-oxide-induced murine oral cancer model. PMID: 22561872
Associations of saposin C, Src, and androgen receptor upregulate the expression and function of androgen receptor in human prostate cancer cells. PMID: 21328455
Regulation of Na+ transport by aldosterone: signaling convergence and cross talk between the PI3-K and MAPK1/2 cascades. PMID: 15039143
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