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Research Grade Vadastuximab (DHD37503)

Host species:Chimeric
Isotype:IgG1-kappa
Applications:Research Grade Biosimilar
Expression system:Mammalian Cells
Overview

Catalog No.

DHD37503

Expression system

Mammalian Cells

Species reactivity

Human

Host species

Chimeric

Isotype

IgG1-kappa

Clonality

Monoclonal

Target

Myeloid cell surface antigen CD33, Sialic acid-binding Ig-like lectin 3, Siglec-3, CD33, gp67, SIGLEC3

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P20138

Applications

Research Grade Biosimilar

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Alternative Names

SGN-CD33A, h2H12ec-SGD-1910, h2H12ec-mc-val-ala-SGD-1882, CAS: 1436390-63-4

Clone ID

Vadastuximab

Data Image
  • SDS-PAGE
    SDS PAGE for Vadastuximab
References

Investigational CD33-targeted therapeutics for acute myeloid leukemia, PMID: 29534618

CD33-Targeted Therapies: Beating the Disease or Beaten to Death?, PMID: 32875599

A phase 1 trial of vadastuximab talirine combined with hypomethylating agents in patients with CD33-positive AML, PMID: 30045838

A phase 1 trial of vadastuximab talirine as monotherapy in patients with CD33-positive acute myeloid leukemia, PMID: 29196412

Emerging therapies for acute myeloid leukemia, PMID: 28420416

Antibody-drug conjugates (ADCs) delivering pyrrolobenzodiazepine (PBD) dimers for cancer therapy, PMID: 32543981

ADCs Show Promise in Leukemias, PMID: 27388473

How can one optimize induction therapy in AML?, PMID: 29156199

Datasheet

Document Download

Research Grade Vadastuximab.pdf

 

$ 328
Product specifications
100 μg 328 1 mg 1314

Contact Information

Order: order@antibodysystem.com

Mail: support@antibodysystem.com

Distributor list

For research use only. Not for human or drug use.

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Research Grade Vadastuximab [DHD37503]
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