Catalog No.
PHB43701
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human ALDH1A2 (Met1-Val422).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Retinaldehyde-specific dehydrogenase type 2, ALDH1A2, Retinal dehydrogenase 2, RALDH2, RALDH(II), Aldehyde dehydrogenase family 1 member A2, RALDH 2, RalDH2
Purification
Purified by antigen affinity column.
Accession
O94788
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Lactobacillus Intestinalis Primes Epithelial Cells to Suppress Colitis-Related Th17 Response by Host-Microbe Retinoic Acid Biosynthesis., PMID:37983567
Peanut protein acts as a TH2 adjuvant by inducing RALDH2 in human antigen-presenting cells., PMID:33378690
CD137 Signaling Regulates Acute Colitis via RALDH2-Expressing CD11b-CD103+ DCs., PMID:32209473
Microbiota Metabolite Short-Chain Fatty Acids Facilitate Mucosal Adjuvant Activity of Cholera Toxin through GPR43., PMID:31076530
Microbiota metabolite short-chain fatty acid acetate promotes intestinal IgA response to microbiota which is mediated by GPR43., PMID:27966553
Beta 1-integrin ligation and TLR ligation enhance GM-CSF-induced ALDH1A2 expression in dendritic cells, but differentially regulate their anti-inflammatory properties., PMID:27897208
Secretory IgA in complex with Lactobacillus rhamnosus potentiates mucosal dendritic cell-mediated Treg cell differentiation via TLR regulatory proteins, RALDH2 and secretion of IL-10 and TGF-β., PMID:26972771
Retinoic acid primes human dendritic cells to induce gut-homing, IL-10-producing regulatory T cells., PMID:25027601
Retinoic acid regulation by CYP26 in vertebrate lens regeneration., PMID:24384390
Prophylactic effect of probiotics on the development of experimental autoimmune myasthenia gravis., PMID:23284891
An effective vaccination approach augments anti-HIV systemic and vaginal immunity in mice with decreased HIV-1 susceptible α4β7high CD4+ T cells., PMID:23157585
Autoantigens in ovarian autoimmunity associated with unexplained infertility and premature ovarian failure., PMID:20522323
Retinoic acid selectively inhibits death of basal vomeronasal neurons during late stage of neural circuit formation., PMID:19519663
Hair cycle-specific immunolocalization of retinoic acid synthesizing enzymes Aldh1a2 and Aldh1a3 indicate complex regulation., PMID:15245423
Distinct functions for Aldh1 and Raldh2 in the control of ligand production for embryonic retinoid signaling pathways., PMID:10570467
For research use only. Not for human or drug use.
