Catalog No.
PHB43701
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human ALDH1A2 (Met1-Val422).
Applications
ELISA, IHC, WB
Recommended Dilution
| Application |
Dilution |
| ELISA |
1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000 |
Target
Retinaldehyde-specific dehydrogenase type 2, ALDH1A2, Retinal dehydrogenase 2, RALDH2, RALDH(II), Aldehyde dehydrogenase family 1 member A2, RALDH 2, RalDH2
Purification
Purified by antigen affinity column.
Accession
O94788
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Note
For research use only.
Distinct functions for Aldh1 and Raldh2 in the control of ligand production for embryonic retinoid signaling pathways., PMID:10570467
Hair cycle-specific immunolocalization of retinoic acid synthesizing enzymes Aldh1a2 and Aldh1a3 indicate complex regulation., PMID:15245423
Retinoic acid selectively inhibits death of basal vomeronasal neurons during late stage of neural circuit formation., PMID:19519663
Autoantigens in ovarian autoimmunity associated with unexplained infertility and premature ovarian failure., PMID:20522323
An effective vaccination approach augments anti-HIV systemic and vaginal immunity in mice with decreased HIV-1 susceptible α4β7high CD4+ T cells., PMID:23157585
Prophylactic effect of probiotics on the development of experimental autoimmune myasthenia gravis., PMID:23284891
Retinoic acid regulation by CYP26 in vertebrate lens regeneration., PMID:24384390
Retinoic acid primes human dendritic cells to induce gut-homing, IL-10-producing regulatory T cells., PMID:25027601
Secretory IgA in complex with Lactobacillus rhamnosus potentiates mucosal dendritic cell-mediated Treg cell differentiation via TLR regulatory proteins, RALDH2 and secretion of IL-10 and TGF-β., PMID:26972771
Beta 1-integrin ligation and TLR ligation enhance GM-CSF-induced ALDH1A2 expression in dendritic cells, but differentially regulate their anti-inflammatory properties., PMID:27897208
Microbiota metabolite short-chain fatty acid acetate promotes intestinal IgA response to microbiota which is mediated by GPR43., PMID:27966553
Microbiota Metabolite Short-Chain Fatty Acids Facilitate Mucosal Adjuvant Activity of Cholera Toxin through GPR43., PMID:31076530
CD137 Signaling Regulates Acute Colitis via RALDH2-Expressing CD11b-CD103+ DCs., PMID:32209473
Peanut protein acts as a TH2 adjuvant by inducing RALDH2 in human antigen-presenting cells., PMID:33378690
Lactobacillus Intestinalis Primes Epithelial Cells to Suppress Colitis-Related Th17 Response by Host-Microbe Retinoic Acid Biosynthesis., PMID:37983567
For research use only. Not for human or drug use.
