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Recombinant ASFV CD2v/pEP402R/CD2H Protein, C-His

Catalog #:   EVV27601 Specific References (92) DATASHEET
Applications: ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Expression system: Mammalian Cells
Accession: YP_009927182.1
Protein length: Asp17-Tyr206
Overview

Catalog No.

EVV27601

Expression system

Mammalian Cells

Species

African swine fever virus

Protein length

Asp17-Tyr206

Predicted molecular weight

25.04 kDa

Nature

Recombinant

Endotoxin level

Please contact with the lab for this information.

Purity

>90% as determined by SDS-PAGE.

Accession

YP_009927182.1

Applications

ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress

Form

Lyophilized

Storage buffer

Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.

Reconstitution

Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.

Shipping

In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Alternative Names

hypothetical protein IM014_gp092, EP402R CDS

Data Image
References

Development and characterization of recombinant ASFV CD2v protein nanoparticle-induced monoclonal antibody. PMID: 35358580

Development of a Dual ELISA for the Detection of CD2v-Unexpressed Lower-Virulence Mutational ASFV. PMID: 34833090

African Swine Fever Virus CD2v Protein Induces β-Interferon Expression and Apoptosis in Swine Peripheral Blood Mononuclear Cells. PMID: 34452346

Identification of Linear B Cell Epitopes on CD2V Protein of African Swine Fever Virus by Monoclonal Antibodies. PMID: 35311572

The recombinant pseudorabies virus expressing African swine fever virus CD2v protein is safe and effective in mice. PMID: 33198749

Deletion of the CD2v Gene from the Genome of ASFV-Kenya-IX-1033 Partially Reduces Virulence and Induces Protection in Pigs. PMID: 36146726

Expression of extracellular domain of ASFV CD2v protein in mammalian cells and identification of B cell epitopes. PMID: 36356676

An Update on African Swine Fever Virology. PMID: 31533244

Subsequent Immunization of Pigs with African Swine Fever Virus (ASFV) Seroimmunotype IV Vaccine Strain FK-32/135 and by Recombinant Plasmid DNA Containing the CD2v Derived from MK-200 ASFV Seroimmunotype III Strain Does Not Protect from Challenge with ASFV Seroimmunotype III. PMID: 37243111

Differential diagnosis of the infection caused by wild-type or CD2v-deleted ASFV strains by quantum dots-based immunochromatographic assay. PMID: 35255156

CD2v Interacts with Adaptor Protein AP-1 during African Swine Fever Infection. PMID: 25915900

African swine fever virus evasion of host defences. PMID: 30959069

Development of an indirect ELISA for the identification of African swine fever virus wild-type strains and CD2v-deleted strains. PMID: 36157191

Processing and localization of the african swine fever virus CD2v transmembrane protein. PMID: 21248037

The CD2v protein of African swine fever virus interacts with the actin-binding adaptor protein SH3P7. PMID: 14718626

Molecular Characterization of African Swine Fever Virus, China, 2018. PMID: 30141772

Development and characterization of monoclonal antibodies against the extracellular domain of African swine fever virus structural protein, CD2v. PMID: 36466651

Roles of African Swine Fever Virus Structural Proteins in Viral Infection. PMID: 29978065

Identification of Two Novel Linear B Cell Epitopes on the CD2v Protein of African Swine Fever Virus Using Monoclonal Antibodies. PMID: 36680174

Construction and Evaluation of Recombinant Pseudorabies Virus Expressing African Swine Fever Virus Antigen Genes. PMID: 35498728

Generation and Evaluation of an African Swine Fever Virus Mutant with Deletion of the CD2v and UK Genes. PMID: 33327488

African Swine Fever Virus Envelope Glycoprotein CD2v Interacts with Host CSF2RA to Regulate the JAK2-STAT3 Pathway and Inhibit Apoptosis to Facilitate Virus Replication. PMID: 37022174

Identification of a new cell-penetrating peptide derived from the african swine fever virus CD2v protein. PMID: 34006158

Host Responses to Live-Attenuated ASFV (HLJ/18-7GD). PMID: 36146810

African Swine Fever Virus HLJ/18 CD2v Suppresses Type I IFN Production and IFN-Stimulated Genes Expression through Negatively Regulating cGMP-AMP Synthase-STING and IFN Signaling Pathways. PMID: 36971697

African swine fever virus CD2v and C-type lectin gene loci mediate serological specificity. PMID: 25524164

[In silico prediction of B- and T-cell epitopes in the CD2v protein of african swine fever virus (African swine fever virus, Asfivirus, Asfarviridae).]. PMID: 32515566

The African Swine Fever Virus with MGF360 and MGF505 Deleted Reduces the Apoptosis of Porcine Alveolar Macrophages by Inhibiting the NF-κB Signaling Pathway and Interleukin-1β. PMID: 34835302

Development of an ELISA Method to Differentiate Animals Infected with Wild-Type African Swine Fever Viruses and Attenuated HLJ/18-7GD Vaccine Candidate. PMID: 36016353

Deletion of CD2-Like (CD2v) and C-Type Lectin-Like (EP153R) Genes from African Swine Fever Virus Georgia-∆9GL Abrogates Its Effectiveness as an Experimental Vaccine. PMID: 33092057

Growth Kinetics and Protective Efficacy of Attenuated ASFV Strain Congo with Deletion of the EP402 Gene. PMID: 34203302

African Swine Fever Virus Hemadsorption Inhibition Assay. PMID: 35575893

Molecular profile of African swine fever virus (ASFV) circulating in Vietnam during 2019-2020 outbreaks. PMID: 33454861

ASFV proteins presented at the surface of T7 phages induce strong antibody responses in mice. PMID: 36965632

Identification of T-cell epitopes in African swine fever virus CD2v and C-type lectin proteins. PMID: 30628881

African swine fever virus proteins involved in evading host defence systems. PMID: 15207450

Flow cytometry-based multiplexing antibody detection for diagnosis of African swine fever virus. PMID: 36038241

Evaluation of Cellular Immunity with ASFV Infection by Swine Leukocyte Antigen (SLA)-Peptide Tetramers. PMID: 34835070

Molecular Characterization of African Swine Fever Virus From 2019-2020 Outbreaks in Guangxi Province, Southern China. PMID: 35782548

The Development of a Multiplex Real-Time Quantitative PCR Assay for the Differential Detection of the Wild-Type Strain and the MGF505-2R, EP402R and I177L Gene-Deleted Strain of the African Swine Fever Virus. PMID: 35883301

Differential antibody responses in sows and finishing pigs naturally infected with African swine fever virus under field conditions. PMID: 34799123

Identification of a linear B-cell epitope on the African swine fever virus CD2v protein. PMID: 36706875

Development and efficacy of a novel mRNA cocktail for the delivery of African swine fever virus antigens and induction of immune responses., PMID:40298440

Characterization of African swine fever virus in Angola, 2024., PMID:40131561

Computational insights in CD58 binding to ASFV CD2v and in silico optimization of nanobody designs against the interface., PMID:40092189

A triple protein-based ELISA for differential detection of ASFV antibodies., PMID:39723184

From structure prediction to function: defining the domain on the African swine fever virus CD2v protein required for binding to erythrocytes., PMID:39688401

How Does African Swine Fever Virus Evade the cGAS-STING Pathway?, PMID:39599510

A plant-based oligomeric CD2v extracellular domain antigen exhibits equivalent immunogenicity to the live attenuated vaccine ASFV-G-∆I177L., PMID:39412651

Protection Evaluation of a New Attenuated ASFV by Deletion of the L60L and CD2v Genes against Homologous Challenge., PMID:39339941

Towards Safe African Swine Fever Vaccines: The A137R Gene as a Tool to Reduce Virulence and a Promising Serological DIVA Marker Candidate., PMID:39272254

Development of novel monoclonal antibodies for blocking NF-κB activation induced by CD2v protein in African swine fever virus., PMID:38846950

Preparation and epitope analysis of monoclonal antibodies against African swine fever virus DP96R protein., PMID:38734611

Nanobodies against African swine fever virus p72 and CD2v proteins as reagents for developing two cELISAs to detect viral antibodies., PMID:38588947

Generation and Characterization of Recombinant Pseudorabies Virus Delivering African Swine Fever Virus CD2v and p54., PMID:38203508

A Robust Quadruple Protein-Based Indirect ELISA for Detection of Antibodies to African Swine Fever Virus in Pigs., PMID:38004769

The CD2v protein of African swine fever virus inhibits macrophage migration and inflammatory cytokines expression by downregulating EGR1 expression through dampening ERK1/2 activity., PMID:37968713

A candidate nanoparticle vaccine comprised of multiple epitopes of the African swine fever virus elicits a robust immune response., PMID:37964304

A protective multiple gene-deleted African swine fever virus genotype II, Georgia 2007/1, expressing a modified non-haemadsorbing CD2v protein., PMID:37781934

Signal peptide and N-glycosylation of N-terminal-CD2v determine the hemadsorption of African swine fever virus., PMID:37768082

Mucosal and cellular immune responses elicited by nasal and intramuscular inoculation with ASFV candidate immunogens., PMID:37720232

Mammalian Cell-Line-Expressed CD2v Protein of African Swine Fever Virus Provides Partial Protection against the HLJ/18 Strain in the Early Infection Stage., PMID:37515155

A new vaccination regimen using adenovirus-vectored vaccine confers effective protection against African swine fever virus in swine., PMID:37401832

Deletion of the CD2 Gene in the Virulent ASFV Congo Strain Affects Viremia in Domestic Swine, but Not the Virulence., PMID:37370512

An Intracellular Epitope of ASFV CD2v Protein Elicits Humoral and Cellular Immune Responses., PMID:37370477

Subsequent Immunization of Pigs with African Swine Fever Virus (ASFV) Seroimmunotype IV Vaccine Strain FK-32/135 and by Recombinant Plasmid DNA Containing the CD2v Derived from MK-200 ASFV Seroimmunotype III Strain Does Not Protect from Challenge with ASFV Seroimmunotype III., PMID:37243111

Evaluation of humoral and cellular immune responses induced by a cocktail of recombinant African swine fever virus antigens fused with OprI in domestic pigs., PMID:37237390

African Swine Fever Virus Envelope Glycoprotein CD2v Interacts with Host CSF2RA to Regulate the JAK2-STAT3 Pathway and Inhibit Apoptosis to Facilitate Virus Replication., PMID:37022174

African Swine Fever Virus HLJ/18 CD2v Suppresses Type I IFN Production and IFN-Stimulated Genes Expression through Negatively Regulating cGMP-AMP Synthase-STING and IFN Signaling Pathways., PMID:36971697

ASFV proteins presented at the surface of T7 phages induce strong antibody responses in mice., PMID:36965632

Dynamics of Serological and Mucosal Antibody Responses against African Swine Fever Viruses in Experimentally Infected Pigs., PMID:40303747

Molecular Characterization of African Swine Fever Viruses Circulating in Can Tho City, Vietnam., PMID:36779206

Identification of a linear B-cell epitope on the African swine fever virus CD2v protein., PMID:36706875

Identification of Two Novel Linear B Cell Epitopes on the CD2v Protein of African Swine Fever Virus Using Monoclonal Antibodies., PMID:36680174

Development and characterization of monoclonal antibodies against the extracellular domain of African swine fever virus structural protein, CD2v., PMID:36466651

Expression of extracellular domain of ASFV CD2v protein in mammalian cells and identification of B cell epitopes., PMID:36356676

Development of an indirect ELISA for the identification of African swine fever virus wild-type strains and CD2v-deleted strains., PMID:36157191

Co-Deletion of A238L and EP402R Genes from a Genotype IX African Swine Fever Virus Results in Partial Attenuation and Protection in Swine., PMID:36146830

Host Responses to Live-Attenuated ASFV (HLJ/18-7GD)., PMID:36146810

Flow cytometry-based multiplexing antibody detection for diagnosis of African swine fever virus., PMID:36038241

Development of an ELISA Method to Differentiate Animals Infected with Wild-Type African Swine Fever Viruses and Attenuated HLJ/18-7GD Vaccine Candidate., PMID:36016353

First Report of a Complete Genome Sequence of a Variant African Swine Fever Virus in the Mekong Delta, Vietnam., PMID:35890041

Comparison of mucosal immune responses to African swine fever virus antigens intranasally delivered with two different viral vectors., PMID:35849881

African Swine Fever Virus Hemadsorption Inhibition Assay., PMID:35575893

Development and characterization of recombinant ASFV CD2v protein nanoparticle-induced monoclonal antibody., PMID:35358580

Identification of Linear B Cell Epitopes on CD2V Protein of African Swine Fever Virus by Monoclonal Antibodies., PMID:35311572

Differential diagnosis of the infection caused by wild-type or CD2v-deleted ASFV strains by quantum dots-based immunochromatographic assay., PMID:35255156

Live pig markets are hotspots for spread of African swine fever virus in Nigeria., PMID:35179830

Molecular characterization of African swine fever viruses from Burkina Faso, 2018., PMID:35151326

In silico analysis of highly conserved cytotoxic T-cell epitopes in the structural proteins of African swine fever virus., PMID:34903918

The African Swine Fever Virus with MGF360 and MGF505 Deleted Reduces the Apoptosis of Porcine Alveolar Macrophages by Inhibiting the NF-κB Signaling Pathway and Interleukin-1β., PMID:34835302

Evaluation of Cellular Immunity with ASFV Infection by Swine Leukocyte Antigen (SLA)-Peptide Tetramers., PMID:34835070

Datasheet
$ 480
Product specifications
100 μg 480 1 mg 2880

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For research use only. Not for human or drug use.

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Recombinant ASFV CD2v/pEP402R/CD2H Protein, C-His [EVV27601]
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