Catalog No.
PHG37401
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human ARHGAP5 (Ser12-Lys248).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Rho-type GTPase-activating protein 5, ARHGAP5, RHOGAP5, p190-B, Rho GTPase-activating protein 5
Purification
Purified by antigen affinity column.
Accession
Q13017
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Interaction of p190RhoGAP with C-terminal domain of p120-catenin modulates endothelial cytoskeleton and permeability., PMID:23653363
Transforming growth factor-beta1 regulates macrophage migration via RhoA., PMID:16705092
PTP-PEST couples membrane protrusion and tail retraction via VAV2 and p190RhoGAP., PMID:16513648
Cell surface transglutaminase promotes RhoA activation via integrin clustering and suppression of the Src-p190RhoGAP signaling pathway., PMID:16452636
Characterization of membrane-localized and cytosolic Rac-GTPase-activating proteins in human neutrophil granulocytes: contribution to the regulation of NADPH oxidase., PMID:11311150
Activation of beta1 integrin signaling stimulates tyrosine phosphorylation of p190RhoGAP and membrane-protrusive activities at invadopodia., PMID:9417037
p190-B, a new member of the Rho GAP family, and Rho are induced to cluster after integrin cross-linking., PMID:8537347
Changes in tyrosine-phosphorylated p190 and its association with p120 type I and p100 type II rasGAPs during myelomonocytic differentiation of human leukemic cells., PMID:7756172
For research use only. Not for human or drug use.
