Catalog No.
YHB87501
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ala356-Asp705
Predicted molecular weight
41.91 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P00736
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
C1R, Complement component 1 subcomponent r, Complement C1r subcomponent
Identification of a Novel Homozygous C1QB Mutation in an Iranian Girl: Expanding the Clinical Spectrum of C1q Deficiency., PMID:40506420
TNFRSF11B-modified umbilical cord mesenchymal stem cells as a novel strategy for bone-related diseases by suppressing osteoclast activity., PMID:40380204
Combining GWAS Summary Data and Proteomics Identified Potential Drug Targets in Dementia., PMID:40266545
Impact of a Heterozygous C1RR301P/WT Mutation on Collagen Metabolism and Inflammatory Response in Human Gingival Fibroblasts., PMID:40214433
The structural characteristics and expression characteristics of C1S in response to GCRV infection in grass carp., PMID:40058677
diaPASEF Analysis for HLA-I Peptides Enables Quantification of Common Cancer Neoantigens., PMID:40044040
Mendelian randomization identifies proteins involved in neurodegenerative diseases., PMID:40037332
Novel drug targets for delirium based on genetic causality., PMID:40023257
Persistence of a Proteomic Signature After a Hypertensive Disorder of Pregnancy., PMID:39981573
Blocking activation of the C1r zymogen defines a novel mode of complement inhibition., PMID:39947467
Guianensin, a Blackfly Salivary Protein, Inhibits the Lectin Pathway of Complement., PMID:39924859
Evaluating SCUBE-1 as Predictive Biomarker for Hypertension-Mediated Organ Damage: A Comparative Study., PMID:39867205
Exploring genetic associations and drug targets for mitochondrial proteins and schizophrenia risk., PMID:39863625
Unraveling antibody-induced structural dynamics in the ADAMTS13 CUB1-2 domains via HDX-MS., PMID:39774799
Complement classical and alternative pathway activation contributes to diabetic kidney disease progression: a glomerular proteomics on kidney biopsies., PMID:39753879
The assessment of the relationship between the development of cardiovascular diseases and SCUBE-1 level in individuals exposed to loud noise., PMID:39705419
Genetic insights into the effect of trace elements on cardiovascular diseases: multi-omics Mendelian randomization combined with linkage disequilibrium score regression analysis., PMID:39691718
Characterising a Novel Therapeutic Target for Psoriasis, TYK2, Using Functional Genomics., PMID:39684939
Divergent changes in complement pathway gene expression in schizophrenia and bipolar disorder: Links to inflammation and neurogenesis in the subependymal zone., PMID:39616737
[Study on serum proteomic characteristics of workers with rare earth samarium oxide pneumoconiosis]., PMID:39604234
Maternal Serum SCUBE-1: A Novel Ischemic Marker in Preeclampsia., PMID:39590594
New insights into the immunomodulatory potential of sialic acid on monocyte-derived dendritic cells., PMID:39487861
Identification of Plasma Protein Biomarkers for Predicting Lung Cancer., PMID:39477293
Protein biomarkers in assessing kidney quality before transplantation‑current status and future perspectives (Review)., PMID:39370783
Immunodeficiency: Complement disorders., PMID:39294906
Unraveling the CDK9/PP2A/ERK Network in Transcriptional Pause Release and Complement Activation in KRAS-mutant Cancers., PMID:39254172
Generation of rabbit single-chain variable fragments with different physicochemical and biological properties by complementary determining region-grafting technology., PMID:39198103
Downregulation of C1R promotes hepatocellular carcinoma development by activating HIF-1α-regulated glycolysis., PMID:39150096
The Establishment of Complement System Is from Gene Duplication and Domain Shuffling., PMID:39125697
Expression and function of the major histocompatibility complex (MHC) class I chain-related A (MICA)*010 in NK cell killing activity., PMID:39116667
Causal relationship between complement C1QB and colorectal cancer: a drug target Mendelian randomization study., PMID:39109334
A novel missense variant in CAT gene causing acatalasemia with gangrenous periodontitis (Takahara's disease)., PMID:39079473
Comparative Proteomic Profiling of Blood Plasma Revealed Marker Proteins Involved in Temporal Lobe Epilepsy., PMID:39063177
Recombinant Ixodes scapularis Calreticulin Binds Complement Proteins but Does Not Protect Borrelia burgdorferi from Complement Killing., PMID:39057787
DNA methylome analysis reveals epigenetic alteration of complement genes in advanced metabolic dysfunction-associated steatotic liver disease., PMID:39048522
Plasma SCUBE2 as a novel biomarker associates with survival outcomes in patients with sepsis-associated acute kidney injury., PMID:39034165
Proteomic profiling of human plasma extracellular vesicles identifies PF4 and C1R as novel biomarker in sarcopenia., PMID:39009419
Familial aggregation of diffuse cutaneous systemic sclerosis: Interplay of C1r gene defect, susceptible HLA haplotype and autoantibodies., PMID:38923752
The Impact of Acute EBV Infection on Changes in the Serum Proteome in Children-A Pilot Study., PMID:38921769
C1s targeting antibodies inhibit the growth of cutaneous squamous carcinoma cells., PMID:38866870
Multifunctional interaction of CihC/FbpC orthologs of relapsing fever spirochetes with host-derived proteins involved in adhesion, fibrinolysis, and complement evasion., PMID:38726006
Tumor Cell-Derived Complement Component C1r Acts as a Prognostic Biomarker and Promotes Esophageal Squamous Cell Carcinoma Progression., PMID:38682192
The molecular determinants of classical pathway complement inhibition by OspEF-related proteins of Borrelia burgdorferi., PMID:38552741
Complement C1s deficiency in a male Caucasian patient with systemic lupus erythematosus: a case report., PMID:38469558
Could signal peptide complement C1r/C1s, Uegf, and Bmp1, and epidermal growth factor-containing protein 1 be a therapeutic target in the pathogenesis of preeclampsia?, PMID:38451587
Tandem Mass Tag-Labeled Quantitative Proteome Analyses Identify C1R and A2M as Novel Serum Biomarkers in Pregnant Women with Obstructive Sleep Apnea., PMID:38407963
Complex changes in serum protein levels in COVID-19 convalescents., PMID:38396092
Herpesvirus activated NF-κB-mediated antigen processing and presentation to aggravate trichloroethylene-induced hypersensitivity dermatitis., PMID:38242488
Comparative transcriptome analysis reveals potential regulatory mechanisms of genes and immune pathways following Vibrio harveyi infection in red drum (Sciaenops ocellatus)., PMID:38242261
Inhibition of the C1s Protease and the Classical Complement Pathway by 6-(4-Phenylpiperazin-1-yl)Pyridine-3-Carboximidamide and Chemical Analogs., PMID:38149922
For research use only. Not for human or drug use.
