Catalog No.
PHK66501
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human PREB (Met1-Ser388).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
PREB, Prolactin regulatory element-binding protein, Mammalian guanine nucleotide exchange factor mSec12, SEC12
Purification
Purified by antigen affinity column.
Accession
Q9HCU5
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Human genetic variation shapes the antibody repertoire across B cell development., PMID:40475565
Insights from the bottom-up development of LGR5-targeting immunotherapeutics., PMID:40405910
Long-term B cell memory emerges at uniform relative rates in the human immune response., PMID:40020190
Mycovirus-Containing Aspergillus flavus Alters Transcription Factors in Normal and Acute Lymphoblastic Leukemia Cells., PMID:39408690
Profiling the impact of anti-human CD20 monoclonal antibodies on lymphocyte B cell subsets and their precursors in the bone marrow and in lymphoid tissues in an immunocompromised mouse engrafted with human cells., PMID:39374887
Transcriptional function of E2A, Ebf1, Pax5, Ikaros and Aiolos analyzed by in vivo acute protein degradation in early B cell development., PMID:39179932
Pre-B cell receptor acts as a selectivity switch for galectin-1 at the pre-B cell surface., PMID:39058594
RAG1/2 induces double-stranded DNA breaks at non-Ig loci in the proximity of single sequence repeats in developing B cells., PMID:39046890
Results of the Simultaneous Combination of Ponatinib and Blinatumomab in Philadelphia Chromosome-Positive ALL., PMID:39028925
YY1-mediated enhancer-promoter communication in the immunoglobulin μ locus is regulated by MSL/MOF recruitment., PMID:38990722
Case report: Sequential inotuzumab, blinatumomab, and chemotherapy with concurrent donor lymphocyte infusions induce complete remission in relapsed pre-B acute lymphoblastic leukemia., PMID:38895070
Fluoxetine Successfully Treats Intracranial Enterovirus E18 Infection in a Patient with CD79a Deficiency Arising from Segmental Uniparental Disomy of Chromosome 19., PMID:38805163
Clinical and Immunologic Features of a Patient With Homozygous FNIP1 Variant., PMID:38748614
Antigen-independent, autonomous B cell receptor signaling drives activated B cell DLBCL., PMID:38512136
Flow cytometric detection of leukemic blasts in Libyan pediatric patients with acute lymphoblastic leukemia., PMID:38394044
Influence of pre-B cell receptor deficiency on the immunoglobulin repertoires in peripheral blood B cells before and after immunization., PMID:38271880
Landscape of protein-protein interactions during hepatitis C virus assembly and release., PMID:38230952
Research Note: Isolation and immunomodulatory activity of bursal peptide, a novel peptide from avian immune system developments., PMID:38042040
Autonomous B-cell receptor signaling and genetic aberrations in chronic lymphocytic leukemia-phenotype monoclonal B lymphocytosis in siblings of patients with chronic lymphocytic leukemia., PMID:37439337
Comparison of Immune-Related Gene Expression in Two Chicken Breeds Following Infectious Bronchitis Virus Vaccination., PMID:37238072
Spi-C and PU.1 Counterregulate Rag1 and Igκ Transcription to Effect Vκ-Jκ Recombination in Small Pre-B Cells., PMID:37195219
Results of salvage therapy with mini-hyper-CVD and inotuzumab ozogamicin with or without blinatumomab in pre-B acute lymphoblastic leukemia., PMID:37131217
Igh and Igk loci use different folding principles for V gene recombination due to distinct chromosomal architectures of pro-B and pre-B cells., PMID:37085514
Astrocytes express aberrant immunoglobulins as putative gatekeeper of astrocytes to neuronal progenitor conversion., PMID:37015912
The evolution of acute lymphoblastic leukemia research and therapy at MD Anderson over four decades., PMID:36927623
Puppet masters of B-cell progenitor acute lymphoblastic leukemia: The preB cell receptor and the interleukin 7 receptor α., PMID:36805963
Myeloid-like B cells boost emergency myelopoiesis through IL-10 production during infection., PMID:36719648
A CRISPR/Cas9-mediated screen identifies determinants of early plasma cell differentiation., PMID:36685499
miR-142 favors naïve B cell residence in peripheral lymph nodes., PMID:36439112
Loss of early B cell protein λ5 decreases bone mass and accelerates skeletal aging., PMID:36189270
Asymmetrical forward and reverse developmental trajectories determine molecular programs of B cell antigen receptor editing., PMID:35930652
RNA exosome drives early B cell development via noncoding RNA processing mechanisms., PMID:35658015
The mammalian SKIV2L RNA exosome is essential for early B cell development., PMID:35658009
Spatial Stochastic Model of the Pre-B Cell Receptor., PMID:35482702
The Small GTPase RHOA Links SLP65 Activation to PTEN Function in Pre B Cells and Is Essential for the Generation and Survival of Normal and Malignant B Cells., PMID:35371049
HLA-G-ILT2 interaction contributes to suppression of bone marrow B cell proliferation in acquired aplastic anemia., PMID:35041051
Nemo-Dependent, ATM-Mediated Signals from RAG DNA Breaks at Igk Feedback Inhibit V κ Recombination to Enforce Igκ Allelic Exclusion., PMID:34965965
THYROID DISEASE IN THE LATE OBSERVATION PERIOD UPON CHEMO AND RADIOTHERAPY IN CHILDREN/SURVIVORS OF ACUTE LYMPHOBLASTIC LEUKEMIA., PMID:34965557
Hygiene Hypothesis as the Etiology of Kawasaki Disease: Dysregulation of Early B Cell Development., PMID:34830213
VpreB surrogate light chain expression in B-lineage ALL: a report from the Children's Oncology Group., PMID:34662891
RAG1 splicing mutation causes enhanced B cell differentiation and autoantibody production., PMID:34622798
Remodelling of Ca2+ homeostasis is linked to enlarged endoplasmic reticulum in secretory cells., PMID:34560367
Radiofrequency EMF irradiation effects on pre-B lymphocytes undergoing somatic recombination., PMID:34135382
Dermatan Sulfate Is a Potential Regulator of IgH via Interactions With Pre-BCR, GTF2I, and BiP ER Complex in Pre-B Lymphoblasts., PMID:34113352
A comparison of the effects of rituximab versus other immunotherapies for MOG-IgG-associated central nervous system demyelination: A meta-analysis., PMID:34091176
PON2 subverts metabolic gatekeeper functions in B cells to promote leukemogenesis., PMID:33531346
CD79a promotes CNS-infiltration and leukemia engraftment in pediatric B-cell precursor acute lymphoblastic leukemia., PMID:33452446
The Ig heavy chain protein but not its message controls early B cell development., PMID:33229554
Case Report: A Case of X-Linked Agammaglobulinemia With High Serum IgE Levels and Allergic Rhinitis., PMID:33224144
For research use only. Not for human or drug use.
