Catalog No.
PHB26301
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human USP2 (Thr275-Met605).
Applications
ELISA, IHC, WB
Recommended Dilution
| Application |
Dilution |
| ELISA |
1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000 |
Target
Ubiquitin thioesterase 2, 41 kDa ubiquitin-specific protease, UBP41, Ubiquitin carboxyl-terminal hydrolase 2, Deubiquitinating enzyme 2, USP2, Ubiquitin-specific-processing protease 2
Purification
Purified by antigen affinity column.
Accession
O75604
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Note
For research use only.
Gene structure, alternate splicing, tissue distribution, cellular localization, and developmental expression pattern of mouse deubiquitinating enzyme isoforms Usp2-45 and Usp2-69., PMID:14686789
A new method of purification of proteasome substrates reveals polyubiquitination of 20 S proteasome subunits., PMID:17189251
Arabidopsis UDP-sugar pyrophosphorylase: evidence for two isoforms., PMID:18768324
Abnormal sperm development in pcd(3J)-/- mice: the importance of Agtpbp1 in spermatogenesis., PMID:21110128
Oxygen regulation of the epithelial Na channel in the collecting duct., PMID:21123494
Ubiquitin-specific protease 2a stabilizes MDM4 and facilitates the p53-mediated intrinsic apoptotic pathway in glioblastoma., PMID:24445145
A COFRADIC protocol to study protein ubiquitination., PMID:24816145
Usp2-69 overexpression slows down the progression of rat anti-Thy1.1 nephritis., PMID:27640956
The transcriptional response of mouse spleen B cells to IL-4: Comparison to the response of human peripheral blood B cells., PMID:30302405
Overexpression of Ubiquitin-Specific Protease 2 (USP2) in the Heart Suppressed Pressure Overload-Induced Cardiac Remodeling., PMID:32963492
Decreased USP2a Expression Inhibits Trophoblast Invasion and Associates With Recurrent Miscarriage., PMID:34489969
Antibody-free approach for ubiquitination profiling by selectively clicking the ubiquitination sites., PMID:36764771
Targeting USP2 regulation of VPRBP-mediated degradation of p53 and PD-L1 for cancer therapy., PMID:37024504
USP2 inhibition unleashes CD47-restrained phagocytosis and enhances anti-tumor immunity., PMID:40379682
For research use only. Not for human or drug use.
