Catalog No.
PXX09501
Species reactivity
Porphyromonas gingivalis
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Porphyromonas gingivalis kgp/prtK (Asp229-Pro683).
Tested applications
ELISA: 1:4000-1:8000, IHC：1:50-1:200, WB: 1:500-1:4000
Target
Lys-gingipain W83, 3.4.22.47, Lysine specific cysteine protease, Lysine-specific cysteine proteinase, Porphypain, PrtK48, Lys-gingipain catalytic subunit, 39 kDa adhesin, PrtK39, 15 kDa adhesin, PrtK15, 44 kDa adhesin, PrtK44, kgp, prtK, prtP
Concentration
0.74 mg/ml
Purification
Purified by antigen affinity column.
Accession
Q51817
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Impacts of Porphyromonas gingivalis periodontitis on rheumatoid arthritis autoimmunity., PMID:37098654
Kgp DNA Vaccine Prevents Experimental Periodontitis., PMID:34918502
Development and Optimization of a Rapid Colorimetric Membrane Immunoassay for Porphyromonas gingivalis., PMID:33820889
Existence of natural mouse IgG mAbs recognising epitopes shared by malondialdehyde acetaldehyde adducts and Porphyromonas gingivalis., PMID:33445998
Identification and Modification of Porphyromonas gingivalis Cysteine Protease, Gingipain, Ideal for Screening Periodontitis., PMID:32582160
Novel synthetic peptide derived from Porphyromonas gingivalis Lys-gingipain detects IgG-mediated host response in periodontitis., PMID:31838319
Role of Acetyltransferase PG1842 in Gingipain Biogenesis in Porphyromonas gingivalis., PMID:30249709
Rapid Chair-Side Test for Detection of Porphyromonas gingivalis., PMID:28182517
Generating and Purifying Fab Fragments from Human and Mouse IgG Using the Bacterial Enzymes IdeS, SpeB and Kgp., PMID:27914089
Presence of Porphyromonas gingivalis in esophagus and its association with the clinicopathological characteristics and survival in patients with esophageal cancer., PMID:26788120
Development and evaluation of a saliva-based chair-side diagnostic for the detection of Porphyromonas gingivalis., PMID:26387647
Prospects for treatment of Porphyromonas gingivalis-mediated disease - immune-based therapy., PMID:26387645
Structure and mechanism of cysteine peptidase gingipain K (Kgp), a major virulence factor of Porphyromonas gingivalis in periodontitis., PMID:25266723
kgp, rgpA, and rgpB DNA vaccines induce antibody responses in experimental peri-implantitis., PMID:24921431
The role of RgpA in the pathogenicity of Porphyromonas gingivalis in the murine periodontitis model., PMID:23909600
Cleavage of IgG1 in gingival crevicular fluid is associated with the presence of Porphyromonas gingivalis., PMID:23116446
The K1K2 region of Lys-gingipain of Porphyromonas gingivalis blocks induction of HLA expression by gamma interferon., PMID:22802347
Diagnostic evaluation of a nanobody with picomolar affinity toward the protease RgpB from Porphyromonas gingivalis., PMID:21569755
Cleavage of protease-activated receptors on an immortalized oral epithelial cell line by Porphyromonas gingivalis gingipains., PMID:19608609
Porphyromonas gingivalis selectively up-regulates the HIV-1 coreceptor CCR5 in oral keratinocytes., PMID:17675516
Role of CD80 and CD86 in host immune responses to the recombinant hemagglutinin domain of Porphyromonas gingivalis gingipain and in the adjuvanticity of cholera toxin B and monophosphoryl lipid A., PMID:17629367
[Clinical association of gingipain K-caspase like subdomain expression of Porphyromonas gingivalis with puberty gingivitis]., PMID:17462155
Kgp and RgpB, but not RgpA, are important for Porphyromonas gingivalis virulence in the murine periodontitis model., PMID:17220315
VimA is part of the maturation pathway for the major gingipains of Porphyromonas gingivalis W83., PMID:17074907
Characterization of proteinase-adhesin complexes of Porphyromonas gingivalis., PMID:16849802
Vaccination with recombinant adhesins from the RgpA-Kgp proteinase-adhesin complex protects against Porphyromonas gingivalis infection., PMID:16839648
Production of protective antibodies against Porphyromonas gingivalis strains by immunization with recombinant gingipain domains., PMID:16831217
Porphyromonas gingivalis-induced platelet aggregation in plasma depends on Hgp44 adhesin but not Rgp proteinase., PMID:16359325
Gingipain-specific IgG in the sera of patients with periodontal disease is necessary for opsonophagocytosis of Porphyromonas gingivalis., PMID:16253083
Inactivation of vimF, a putative glycosyltransferase gene downstream of vimE, alters glycosylation and activation of the gingipains in Porphyromonas gingivalis W83., PMID:15972484
Effectiveness of the B subunit of cholera toxin in potentiating immune responses to the recombinant hemagglutinin/adhesin domain of the gingipain Kgp from Porphyromonas gingivalis., PMID:15955601
Altered gingipain maturation in vimA- and vimE-defective isogenic mutants of Porphyromonas gingivalis., PMID:15731033
The C-terminal domains of the gingipain K polyprotein are necessary for assembly of the active enzyme and expression of associated activities., PMID:15554977
The vimE gene downstream of vimA is independently expressed and is involved in modulating proteolytic activity in Porphyromonas gingivalis W83., PMID:15385452
Suppression of pathogenicity of Porphyromonas gingivalis by newly developed gingipain inhibitors., PMID:15361547
Serum antibodies against the hemoglobin-binding domain (HA2) of Porphyromonas gingivalis., PMID:15206915
Porphyromonas gingivalis gingipains: the molecular teeth of a microbial vampire., PMID:14683427
Antibody responses of periodontitis patients to gingipains of Porphyromonas gingivalis., PMID:14653388
Antibody responses to Porphyromonas gingivalis infection in a murine abscess model--involvement of gingipains and responses to re-infection., PMID:14632916
Gingipains as candidate antigens for Porphyromonas gingivalis vaccine., PMID:14529148
A naturally occurring NAR variable domain binds the Kgp protease from Porphyromonas gingivalis., PMID:11959108
Immunization with the RgpA-Kgp proteinase-adhesin complexes of Porphyromonas gingivalis protects against periodontal bone loss in the rat periodontitis model., PMID:11953385
Major outer membrane proteins and proteolytic processing of RgpA and Kgp of Porphyromonas gingivalis W50., PMID:11903053
LuxS-dependent quorum sensing in Porphyromonas gingivalis modulates protease and haemagglutinin activities but is not essential for virulence., PMID:11882711
Role of RgpA, RgpB, and Kgp proteinases in virulence of Porphyromonas gingivalis W50 in a murine lesion model., PMID:11705929
Functional characteristics of antibodies induced by Arg-gingipain (HRgpA) and Lys-gingipain (Kgp) from Porphyromonas gingivalis., PMID:11442844
Specific antibodies to Porphyromonas gingivalis Lys-gingipain by DNA vaccination inhibit bacterial binding to hemoglobin and protect mice from infection., PMID:11292714
Proteolysis of human monocyte CD14 by cysteine proteinases (gingipains) from Porphyromonas gingivalis leading to lipopolysaccharide hyporesponsiveness., PMID:10861079
RgpA-Kgp peptide-based immunogens provide protection against Porphyromonas gingivalis challenge in a murine lesion model., PMID:10858222
Serum immunoglobulin G (IgG) and IgG subclass responses to the RgpA-Kgp proteinase-adhesin complex of Porphyromonas gingivalis in adult periodontitis., PMID:10768963
For research use only. Not for human or drug use.
