Catalog No.
PHC59201
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human UBB (Met1-Gly76).
Applications
ELISA, IHC, WB
Recommended Dilution
| Application |
Dilution |
| ELISA |
1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000 |
Target
Polyubiquitin-B,UBB
Purification
Purified by antigen affinity column.
Accession
P0CG47
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Note
For research use only.
Urinary excretion of tubular brush-border antigens among lead exposed workers., PMID:7847742
The Mallory body as an aggresome: in vitro studies., PMID:11784119
Coexpression and accumulation of ubiquitin +1 and ZZ proteins in livers of children with alpha(1)-antitrypsin deficiency., PMID:12007022
The role of the ubiquitin-proteasome pathway in the formation of mallory bodies., PMID:12231209
The mechanism of cytokeratin aggresome formation: the role of mutant ubiquitin (UBB+1)., PMID:12710947
Heat shock proteins are present in mallory bodies (cytokeratin aggresomes) in human liver biopsy specimens., PMID:12710948
Disease-specific accumulation of mutant ubiquitin as a marker for proteasomal dysfunction in the brain., PMID:14597671
Accumulation of aberrant ubiquitin induces aggregate formation and cell death in polyglutamine diseases., PMID:15198995
Mallory body forming cells express the preneoplastic hepatocyte phenotype., PMID:16413534
Expression of mutant ubiquitin (UBB+1) and p62 in myotilinopathies and desminopathies., PMID:17931355
Mutant ubiquitin-mediated beta-secretase stability via activation of caspase-3 is related to beta-amyloid accumulation in ischemic striatum in rats., PMID:19844237
A novel PRNP Y218N mutation in Gerstmann-Sträussler-Scheinker disease with neurofibrillary degeneration., PMID:20613639
A unique homologue of the eukaryotic protein-modifier ubiquitin present in the bacterium Bacteroides fragilis, a predominant resident of the human gastrointestinal tract., PMID:21885481
Cellular protein quality control and the evolution of aggregates in spinocerebellar ataxia type 3 (SCA3)., PMID:21916928
Identification and characterization of RING-finger ubiquitin ligase UBR7 in mammalian spermatozoa., PMID:24664117
PBMC transcriptome profiles identifies potential candidate genes and functional networks controlling the innate and the adaptive immune response to PRRSV vaccine in Pietrain pig., PMID:28278192
Antigenic mimicry of ubiquitin by the gut bacterium Bacteroides fragilis: a potential link with autoimmune disease., PMID:30076785
Upregulation of ubiquitinated proteins and their degradation pathway in muscle atrophy induced by cisplatin in mice., PMID:32738330
Identification of key genes and imbalance of immune cell infiltration in immunoglobulin A associated vasculitis nephritis by integrated bioinformatic analysis., PMID:37026011
The role of PCSK9 in heart failure and other cardiovascular diseases-mechanisms of action beyond its effect on LDL cholesterol., PMID:38886277
An Uncommon Overlap Syndrome Between Ankylosing Spondylitis and Amyotrophic Lateral Sclerosis-Case Report., PMID:39459490
Integrative Modeling in the Age of Machine Learning: A Summary of HADDOCK Strategies in CAPRI Rounds 47-55., PMID:39739354
For research use only. Not for human or drug use.
