Catalog No.
YHE77101
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Arg80-Ser228
Predicted molecular weight
43.74 kDa
Nature
Recombinant
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P50539
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
BHLHC11, Max-interacting protein 1, MXI1, Max interactor 1, bHLHc11, Class C basic helix-loop-helix protein 11
Note
For research use only.
Identification and characterization of lncRNA mediated transcriptional dysregulation dictates lncRNA roles in glioblastoma., PMID:26943771
Restoration of MYC-repressed targets mediates the negative effects of GM-CSF on RUNX1-ETO leukemogenicity., PMID:27389055
A positive feedback loop between ROS and Mxi1-0 promotes hypoxia-induced VEGF expression in human hepatocellular carcinoma cells., PMID:28065785
Transcriptional reprogramming in yeast using dCas9 and combinatorial gRNA strategies., PMID:28298224
Mxi1-0 regulates the growth of human umbilical vein endothelial cells through extracellular signal-regulated kinase 1/2 (ERK1/2) and interleukin-8 (IL-8)-dependent pathways., PMID:28575053
CRISPRi repression of nonhomologous end-joining for enhanced genome engineering via homologous recombination in Yarrowia lipolytica., PMID:28832943
Effect of Huaier On the Proliferation of Mesangial Cells in Anti-Thy-1 Nephritis., PMID:28848114
Interaction of RNA-binding protein HuR and miR-466i regulates GM-CSF expression., PMID:29222492
An integrative analysis of DNA methylation in osteosarcoma., PMID:29234590
Identification of novel fusion transcripts in multiple myeloma., PMID:29453220
S6K1 phosphorylation-dependent degradation of Mxi1 by β-Trcp ubiquitin ligase promotes Myc activation and radioresistance in lung cancer., PMID:29507620
CRISPR-Mediated Genome Editing and Gene Repression in Scheffersomyces stipitis., PMID:29917323
FOXO3a-dependent up-regulation of Mxi1-0 promotes hypoxia-induced apoptosis in endothelial cells., PMID:30118760
Anti-CRISPR-based biosensors in the yeast S. cerevisiae., PMID:30123320
Screening of key candidate genes and pathways for osteocytes involved in the differential response to different types of mechanical stimulation using a bioinformatics analysis., PMID:30413886
A CRISPR Interference Platform for Efficient Genetic Repression in Candida albicans., PMID:30760609
Optogenetic Repressors of Gene Expression in Yeasts Using Light-Controlled Nuclear Localization., PMID:31719930
RUNX1 contributes to the mesenchymal subtype of glioblastoma in a TGFβ pathway-dependent manner., PMID:31754093
Guide RNA Engineering Enables Dual Purpose CRISPR-Cpf1 for Simultaneous Gene Editing and Gene Regulation in Yarrowia lipolytica., PMID:32208677
FTO Inhibition Enhances the Antitumor Effect of Temozolomide by Targeting MYC-miR-155/23a Cluster-MXI1 Feedback Circuit in Glioma., PMID:32680921
MiR-93/miR-375: Diagnostic Potential, Aggressiveness Correlation and Common Target Genes in Prostate Cancer., PMID:32784653
A MXI1-NUTM1 fusion protein with MYC-like activity suggests a novel oncogenic mechanism in a subset of NUTM1-rearranged tumors., PMID:32873880
A CRISPR activation and interference toolkit for industrial Saccharomyces cerevisiae strain KE6-12., PMID:32884066
UBE2O targets Mxi1 for ubiquitination and degradation to promote lung cancer progression and radioresistance., PMID:32901121
Critical role of HOX transcript antisense intergenic RNA (HOTAIR) in gliomas., PMID:32978667
Transcriptional network modulated by the prognostic signature transcription factors and their long noncoding RNA partners in primary prostate cancer., PMID:33279858
Analysis of Differentially Expressed Genes in the Dentate Gyrus and Anterior Cingulate Cortex in a Mouse Model of Depression., PMID:33628784
Efficient multiplexed gene regulation in Saccharomyces cerevisiae using dCas12a., PMID:34197613
Functional variant rs2270363 on 16p13.3 confers schizophrenia risk by regulating NMRAL1., PMID:35094059
Arginine methyltransferase PRMT5 methylates and destabilizes Mxi1 to confer radioresistance in non-small cell lung cancer., PMID:35149174
Suppression of tumor metastasis by a RECK-activating small molecule., PMID:35149728
Mxi1-0 Promotes Hypoxic Pulmonary Hypertension Via ERK/c-Myc-dependent Proliferation of Arterial Smooth Muscle Cells., PMID:35401684
Cytomorphology of NUTM1-rearranged sarcoma involving pleural fluid., PMID:35441831
Mxi1 participates in the progression of lung cancer via the microRNA-300/KLF9/GADD34 Axis., PMID:35501353
Development of a Risk Score Model for Osteosarcoma Based on DNA Methylation-Driven Differentially Expressed Genes., PMID:35602303
Clinicopathologic features of an MXI1::NUTM1 fusion neoplasm; a new molecular variant of the family of NUTM1-rearranged neoplasm., PMID:35791777
Max interacting protein 1 induces IL-17-producing T helper/regulatory T imbalance in osteoarthritis by upregulating tectonic family member 2., PMID:36049372
Case report: NUT carcinoma with MXI1::NUTM1 fusion characterized by abdominopelvic lesions and ovarian masses in a middle-aged female., PMID:36741693
Grouper annexin A2 affects RGNNV by regulating the host immune response., PMID:37100308
Sarcoma with MGA::NUTM1 fusion: a report of three cases and literature review., PMID:37442637
USP31 serves as a potential biomarker for predicting prognosis and immune responses for clear cell renal cell carcinoma via single-cell and bulk RNA-sequencing., PMID:37699648
Identification of M5c regulator-medicated methylation modification patterns for prognosis and immune microenvironment in glioma., PMID:37934565
Transcriptional profile of human thymus reveals IGFBP5 is correlated with age-related thymic involution., PMID:38318192
Expanding the Spectrum of NUTM1 -Rearranged Sarcoma : A Clinicopathologic and Molecular Genetic Study of 8 Cases., PMID:38946048
Identification of the shared gene MXD3 signatures and biological mechanism in patients with hip pain and prostate cancer., PMID:39287260
Genome-wide association studies of COVID-19 vaccine seroconversion and breakthrough outcomes in UK Biobank., PMID:39384777
MAD::NUT Fusion Sarcoma: A Sarcoma Class With NUTM1, NUTM2A, and NUTM2G Fusions and Possibly Distinctive Subtypes., PMID:39921028
Advancing Understanding and Therapeutic Strategies for NUT Sarcomas: Comprehensive Review of the Literature and Two Cases., PMID:40070529
Establishment of CRISPR-STAR System to Realise Simultaneous Transcriptional Activation and Repression in Yarrowia lipolytica., PMID:40275527
The Emerging Role and Mechanism of E2/E3 Hybrid Enzyme UBE2O in Human Diseases., PMID:40426910
For research use only. Not for human or drug use.
