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Anti-MPO Polyclonal Antibody

Catalog #:   PHC14801 Specific References (50) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: ELISA, IHC, WB
Accession: P05164
Overview

Catalog No.

PHC14801

Species reactivity

Human, Mouse, Rat

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human MPO (Val165-Gly278).

Applications

ELISA, IHC, WB

Recommended Dilution

Application Dilution
ELISA 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

Myeloperoxidase,MPO

Concentration

1.21 mg/ml

Purification

Purified by antigen affinity column.

Accession

P05164

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Note

For research use only.

Data Image
  • WESTERN-BLOT
    Various lysates were subjected to SDS PAGE followed by western blot with MPO antibody (PHC14801) at 1 µg/ml.

    Lane 1: HL-60 cell lysate

    Second Ab: Goat Anti-Rabbit IgG H&L Polyclonal antibody, HRP (PTB96431) at 0.1 μg/mL.

    Predict MW: 84 kDa
    Observed MW: 84 kDa
  • WESTERN BLOT
    Recombinant Protein lysates were subjected to SDS PAGE followed by western blot with MPO antibody (PHC14801) at 1 μg/ml.

    Lane 1: Recombinant protein

    Second Ab: Goat Anti-Rabbit IgG H&L Polyclonal antibody, HRP (PTB96431) at 0.1 μg/mL.

    Predict MW: 13 kDa
    Observed MW: 13 kDa
References

Aberrant oxidative modifications of neutrophil myeloperoxidase in anti-neutrophil cytoplasmic antibody-associated vasculitis., PMID:39993524

The role and mechanism study of Cxcl14 in chronic critically ill cardiac dysfunction., PMID:40010139

Sequential carbonyl derivatives and hydrazone adduct formation on myeloperoxidase contribute to development of ANCA vasculitis., PMID:40020049

Polymorphonuclear neutrophil depletion in ileal tissues reduces the immunopathology induced by Clostridioides difficile toxins., PMID:40023364

Diffuse Alveolar Hemorrhage Linked to Hydralazine., PMID:40026554

In-Depth Analysis of Disease Manifestations in Antineutrophil Cytoplasmic Antibody-Associated Vasculitides Identifies Distinct Clinical Phenotypes., PMID:40033657

The prevalence of primary chronic rhinosinusitis in young adults from a Swedish birth cohort., PMID:40042341

Association of C4d with disease activity in anti-neutrophil cytoplasmic antibody-associated vasculitis: evidence for classical/lectin complement pathway activation., PMID:40045390

Differences in Radiological and Pathological Findings by ANCA-Subtype in ANCA-Positive Idiopathic Interstitial Pneumonias., PMID:40070290

Highlights from the breakout session: cellular and molecular mechanisms of disease (II)., PMID:40071399

Emerging cell therapies in the vasculitis field., PMID:40071405

Interstitial lung disease, antineutrophil cystoplasmic antibodies and microscopic polyangiitis., PMID:40071415

Highlights from the plenary session: cellular and molecular mechanisms of disease (I)., PMID:40071418

The evolving landscape of vasculitis management: past, current and emerging., PMID:40071421

Novel Methods for the Analysis of Serum NET Remnants: Evaluation in Patients with Severe COVID-19., PMID:40076841

Current Diagnosis and Treatment of Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis: A Review Including a Comparison of Characteristics in Europe and Japan., PMID:40095851

Simplifying ANCA-associated vasculitis classification with ANCA specificity: a retrospective analysis., PMID:40100609

Long-Term Clinical Landscapes of Spinal Hypertrophic Pachymeningitis With Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis., PMID:40106756

T-bet+ CXCR3+ B cells drive hyperreactive B-T cell interactions in multiple sclerosis., PMID:40107244

The application of neutrophil extracellular traps to thrombus age Estimation in rat deep vein thrombosis model., PMID:40111724

Endothelial but not systemic ferroptosis inhibition protects from antineutrophil cytoplasmic antibody-induced crescentic glomerulonephritis., PMID:40122342

Cardiac Macrophages Promote Polarization of Macrophages toward M2 Phenotype to Improve Myocardial Remodeling via NGAL after Myocardial Infarction., PMID:40138155

Status of initial treatment for rapidly progressive glomerulonephritis in Japan: analysis of a personal clinical records database., PMID:40146365

4D label-free quantitative proteomic and phosphoproteomic profiling of the kidney in rat models of antimyeloperoxidase-associated vasculitis., PMID:40201969

Successful treatment of MPO-ANCA positive crescentic IgA nephropathy/IgA vasculitis with nephritis potentially triggered by a COVID-19 vaccine in a young adult female using corticosteroids, rituximab, and avacopan., PMID:40202709

A Diagnostic Dilemma: Proteinase-3 (PR3)-Positive Anti-neutrophil Cytoplasmic Autoantibodies in Eosinophilic Granulomatosis With Polyangiitis., PMID:40206908

False Positive C-ANCA Caused by Antinuclear Antibody: a Case Report and Literature Review., PMID:40209788

Overlap Syndrome in Late-Onset Systemic Lupus Erythematosus With Lupus Nephritis and MPO-ANCA Pauci-Immune Glomerulonephritis and Tuberculosis: An Uncommon Association., PMID:40212399

Prevalence and clinical significance of anti-neutrophil cytoplasmic antibodies in rheumatoid arthritis-associated interstitial lung disease., PMID:40229742

Haptenization as the missing link between vasculitis and myeloperoxidase., PMID:40231470

A Case of Hydralazine-Induced ANCA Vasculitis/Lupus Overlap Syndrome Presenting as Persistent Bicytopenia., PMID:40242048

Drug-Induced Renal Vasculitis: Etiology, Pathogenesis, Clinical Manifestations, and Therapeutic Approaches-A Narrative Review., PMID:40242254

Early Intervention with Mepolizumab, Corticosteroids, and Intravenous Immunoglobulin for Dupilumab-Triggered Eosinophilic Granulomatosis with Polyangiitis: A Case Report., PMID:40248105

A case of rapidly progressive IgA nephropathy after SARS-CoV-2 vaccination, successfully treated with cyclophosphamide., PMID:40252186

Assessment of Patients With Beta-Lactams Positive Provocation Tests by Biomarkers of IgG-Related Neutrophil Activation., PMID:40268517

Interstitial lung disease in patients with antineutrophil cytoplasmic antibody-associated vasculitis: chest CT patterns and correlation with survival., PMID:40273744

Polyunsaturated Fatty Acids Improved Long Term Prognosis by Reducing Oxidative Stress, Inflammation, and Endothelial Dysfunction in Acute Coronary Syndromes., PMID:40278275

Curcumin Attenuates PD-L1-Positive Neutrophil-Induced T-Lymphocyte Apoptosis and Alleviates Lung Injury During Sepsis in Rats., PMID:40287812

Methimazole-Induced Pancytopenia with ANCA Positivity: Diagnostic and Management Challenges., PMID:40320692

Damage accrual and predictors of mortality in ANCA-associated vasculitis: a retrospective observational study., PMID:40332571

Atypical Presentation of Microscopic Polyangiitis in an Elderly Woman., PMID:40406763

A Nanoparticle-Based Immunoassay on Facemasks for Evaluating Neutrophilic Airway Inflammation in COPD Patients., PMID:40422062

MPO-ANCA-Associated Hypertrophic Pachymeningitis Mimicking IgG4-Related Disease: A Case Report and Literature Review., PMID:40438183

Clinical significance of anti-neutrophil cytoplasmic antibody in idiopathic interstitial pneumonia: a retrospective observational study., PMID:40442650

Two unique cases of eosinophilic granulomatosis with polyangiitis in childhood treated with anti-interleukin-5 therapy: infantile-onset and submandibular salivary gland involvement., PMID:40457436

A Retrospective Observational Study of Otitis Media with Anti-neutrophil Cytoplasmic Antibody-associated Vasculitis., PMID:40467500

The Utility of Myeloperoxidase Immunostaining to Characterize Immune Deposits in Patients With Crescentic Glomerulonephritis., PMID:40485711

A Case of Synovitis Acne Pustulosis Hyperostosis Osteitis (SAPHO) Syndrome With Myeloperoxidase Anti-neutrophil Cytoplasmic Antibody: Exploring an Association or Coincidence., PMID:40497194

Robust Serum Proteomic Signatures of APOE2., PMID:40501769

Neutrophil Extracellular Traps in Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis: Diagnostic and Clinical Significance-A Review of the Current Literature., PMID:40507398

Datasheet

Document Download

Anti-MPO Polyclonal Antibody.pdf

 

$ 170
Product specifications
50 μg 170 100 μg 280

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For research use only. Not for human or drug use.

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Anti-MPO Polyclonal Antibody [PHC14801]
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