Catalog No.
VHJ97801
Species reactivity
Human
Host species
Human
Isotype
IgG1, kappa
Clonality
Monoclonal
Target
IEGF, PDGFD latent form, PDGF-D, Spinal cord-derived growth factor B, SCDGF-B, Iris-expressed growth factor, PDGFD, Platelet-derived growth factor D, PDGFD receptor-binding form, SCDGFB
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q9GZP0
Applications
ELISA, Neutralization
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
Iv0074
Effect of HepG2-Derived Exosome with PDGF-D Knockdown on Transformation of Normal Fibroblasts into Tumor-Associated Fibroblasts in Liver Cancer., PMID:40152369
PDGF-D Is Dispensable for the Development and Progression of Murine Alport Syndrome., PMID:38309427
High-precision targeting and destruction of cancer-associated PDGFR-β+ stromal fibroblasts through self-assembling, protein-only nanoparticles., PMID:37683965
Reversible promoter demethylation of PDGFD confers gemcitabine resistance through STAT3 activation and RRM1 upregulation., PMID:37321532
Perivascular localized cells commit erythropoiesis in PDGF-B-expressing solid tumors., PMID:37120719
PDGF-D-induced immunoproteasome activation and cell-cell interactions., PMID:37066124
Combination therapy with chitosan/siRNA nanoplexes targeting PDGF-D and PDGFR-β reveals anticancer effect in breast cancer., PMID:36413571
Diabetes impairs cardioprotective function of endothelial progenitor cell-derived extracellular vesicles via H3K9Ac inhibition., PMID:35673580
Chitosan Modification-Enhanced Silencing Effect of Ad5-shPDGF-D Vector in Breast Cancer Cell Line MDA-MB-231., PMID:35507787
Downregulation of NCL attenuates tumor formation and growth in HeLa cells by targeting the PI3K/AKT pathway., PMID:35128835
The HIF1α-PDGFD-PDGFRα axis controls glioblastoma growth at normoxia/mild-hypoxia and confers sensitivity to targeted therapy by echinomycin., PMID:34470658
Downregulation of PDGF-D Inhibits Proliferation and Invasion in Breast Cancer MDA-MB-231 Cells., PMID:34272173
Asparanin A inhibits cell migration and invasion in human endometrial cancer via Ras/ERK/MAPK pathway., PMID:33561516
First trimester placental mesenchymal stem cells improve cardiac function of rat after myocardial infarction via enhanced neovascularization., PMID:33553765
Exosomes Released from CaSR-Stimulated PMNs Reduce Ischaemia/Reperfusion Injury., PMID:33505580
Meningitic Escherichia coli-induced upregulation of PDGF-B and ICAM-1 aggravates blood-brain barrier disruption and neuroinflammatory response., PMID:31092253
Cytomegalovirus promotes murine glioblastoma growth via pericyte recruitment and angiogenesis., PMID:30855281
Platelet-derived growth factor-D enables liver myofibroblasts to promote tumor lymphangiogenesis in cholangiocarcinoma., PMID:30553841
A recombinant lentiviral PDGF-driven mouse model of proneural glioblastoma., PMID:29016807
Exosomes Derived from Akt-Modified Human Umbilical Cord Mesenchymal Stem Cells Improve Cardiac Regeneration and Promote Angiogenesis via Activating Platelet-Derived Growth Factor D., PMID:28170176
PDGF-D promotes cell growth, aggressiveness, angiogenesis and EMT transformation of colorectal cancer by activation of Notch1/Twist1 pathway., PMID:28035069
ZIC5 Drives Melanoma Aggressiveness by PDGFD-Mediated Activation of FAK and STAT3., PMID:27671679
The role of PDGF-D in healthy and fibrotic kidneys., PMID:26924050
Clopidogrel significantly lowers the development of atherosclerosis in ApoE-deficient mice in vivo., PMID:26062773
Naturally occurring PDGF receptor inhibitors with potential anti-atherosclerotic properties., PMID:25737405
The pivotal role of PDGF and its receptor isoforms in adipose-derived stem cells., PMID:25712449
Pax3 expression enhances PDGF-B-induced brainstem gliomagenesis and characterizes a subset of brainstem glioma., PMID:25330836
Gastric cancer-derived MSC-secreted PDGF-DD promotes gastric cancer progression., PMID:24938433
Investigation of the hepatotoxicity of flutamide: pro-survival/apoptotic and necrotic switch in primary rat hepatocytes characterized by metabolic and transcriptomic profiles in microfluidic liver biochips., PMID:24793618
Over-expression of platelet-derived growth factor-D promotes tumor growth and invasion in endometrial cancer., PMID:24646915
A critical role of the PTEN/PDGF signaling network for the regulation of radiosensitivity in adenocarcinoma of the prostate., PMID:24331662
Platelet-derived growth factor-D and Rho GTPases regulate recruitment of cancer-associated fibroblasts in cholangiocarcinoma., PMID:23505219
Differential tumorigenic potential and matriptase activation between PDGF B versus PDGF D in prostate cancer., PMID:22689130
Cediranib inhibits both the intraosseous growth of PDGF D-positive prostate cancer cells and the associated bone reaction., PMID:22213159
Induction of progressive glomerulonephritis by podocyte-specific overexpression of platelet-derived growth factor-D., PMID:21866094
Human umbilical cord blood stem cells show PDGF-D-dependent glioma cell tropism in vitro and in vivo., PMID:20406896
Platelet-derived growth factor-DD targeting arrests pathological angiogenesis by modulating glycogen synthase kinase-3beta phosphorylation., PMID:20231273
Platelet-derived growth factor isoform expression in carbon tetrachloride-induced chronic liver injury., PMID:18663351
Platelet-derived growth factor-D overexpression contributes to epithelial-mesenchymal transition of PC3 prostate cancer cells., PMID:18403754
PDGF-C and -D induced proliferation/migration of human RPE is abolished by inflammatory cytokines., PMID:18055825
The role of PDGF-D in mesangioproliferative glomerulonephritis., PMID:17495455
Neurocytoma is a tumor of adult neuronal progenitor cells., PMID:17135416
Antagonism of PDGF-D by human antibody CR002 prevents renal scarring in experimental glomerulonephritis., PMID:16510766
Platelet-derived growth factor D induces cardiac fibrosis and proliferation of vascular smooth muscle cells in heart-specific transgenic mice., PMID:16224065
Blocking platelet-derived growth factor-D/platelet-derived growth factor receptor beta signaling inhibits human renal cell carcinoma progression in an orthotopic mouse model., PMID:15994946
Platelet-derived growth factor D, tissue-specific expression in the eye, and a key role in control of lens epithelial cell proliferation., PMID:15611105
PDGF-D induces macrophage recruitment, increased interstitial pressure, and blood vessel maturation during angiogenesis., PMID:15271796
Platelet-derived growth factor exerts disparate effects on odontoblast differentiation depending on the dimers in rat dental pulp cells., PMID:14740293
Modulation of PDGF-C and PDGF-D expression during bleomycin-induced lung fibrosis., PMID:12972405
For research use only. Not for human or drug use.
