Catalog No.
YVV17501
Expression system
E. coli
Species
Human papillomavirus 52
Protein length
Met1-Val148
Predicted molecular weight
20.06 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P36814
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Protein E6, E6
Genetic variation of E6 and E7 genes of human papillomavirus 52 from Central China. PMID: 33230866
The possible impact of novel mutations in human papillomavirus 52 on the infection characteristics. PMID: 37103992
Characteristics of human papillomavirus infection among females and the genetic variations of HPV18 and HPV58 in Henan province, China. PMID: 36755053
Genetic variability in the E6 and E7 oncogenes of HPV52 and its prevalence in the Taizhou area, China. PMID: 36415002
The HPV E6/E7 Oncogenes: Key Factors for Viral Carcinogenesis and Therapeutic Targets. PMID: 28823569
Structure of the E6/E6AP/p53 complex required for HPV-mediated degradation of p53. PMID: 26789255
Structure and function of the papillomavirus E6 protein and its interacting proteins. PMID: 17981532
Effects of HPV16 E6 protein on Daxx-induced apoptosis in C33A cells. PMID: 32782452
[Expression of HPV16 E6 recombinant protein and preparation of its rabbit polyclonal antibody]. PMID: 32389175
Structure of High-Risk Papillomavirus 31 E6 Oncogenic Protein and Characterization of E6/E6AP/p53 Complex Formation. PMID: 33115863
The ubiquitin-protein ligase E6-associated protein (E6-AP) serves as its own substrate. PMID: 9688277
Determinants of stability for the E6 protein of papillomavirus type 16. PMID: 19244625
High-Risk Mucosal Human Papillomavirus 16 (HPV16) E6 Protein and Cutaneous HPV5 and HPV8 E6 Proteins Employ Distinct Strategies To Interfere with Interferon Regulatory Factor 3-Mediated Beta Interferon Expression. PMID: 35475668
The high-risk HPV E6 proteins modify the activity of the eIF4E protein via the MEK/ERK and AKT/PKB pathways. PMID: 32981220
Differential localization of HPV16 E6 splice products with E6-associated protein. PMID: 15960845
The HPV-16 E6 and E6-AP complex functions as a ubiquitin-protein ligase in the ubiquitination of p53. PMID: 8221889
HPV16 E6 Controls the Gap Junction Protein Cx43 in Cervical Tumour Cells. PMID: 26445057
E6^E7, a novel splice isoform protein of human papillomavirus 16, stabilizes viral E6 and E7 oncoproteins via HSP90 and GRP78. PMID: 25691589
Design of a PDZbody, a bivalent binder of the E6 protein from human papillomavirus. PMID: 25797137
Strategies for bacterial expression of protein-peptide complexes: application to solubilization of papillomavirus E6. PMID: 21777678
The HPV16 E6 binding protein Tip-1 interacts with ARHGEF16, which activates Cdc42. PMID: 21139582
Ubiquitin-dependent proteolysis of trihydrophobin 1 (TH1) by the human papilloma virus E6-associated protein (E6-AP). PMID: 17131388
Human papillomavirus type 18 E6*, E6, and E7 protein synthesis in cell-free translation systems and comparison of E6 and E7 in vitro translation products to proteins immunoprecipitated from human epithelial cells. PMID: 1651423
Identification of the HPV-16 E6 protein from transformed mouse cells and human cervical carcinoma cell lines. PMID: 3036495
E6 protein of human papillomavirus 16 (HPV16) expressed in Escherichia coli sans a stretch of hydrophobic amino acids, enables purification of GST-ΔE6 in the soluble form and retains the binding ability to p53. PMID: 24012792
Targeted degradation of the retinoblastoma protein by human papillomavirus E7-E6 fusion proteins. PMID: 1321031
Cloning and expression of the cDNA for E6-AP, a protein that mediates the interaction of the human papillomavirus E6 oncoprotein with p53. PMID: 8380895
Is viral E6 oncoprotein a viable target? A critical analysis in the context of cervical cancer. PMID: 32483862
Alternatively spliced HPV-18 E6* protein inhibits E6 mediated degradation of p53 and suppresses transformed cell growth. PMID: 9233760
The E6 protein of human papillomavirus type 16 binds to and inhibits co-activation by CBP and p300. PMID: 10487758
Human papillomavirus type 16 E6 protein interacts with cystic fibrosis transmembrane regulator-associated ligand and promotes E6-associated protein-mediated ubiquitination and proteasomal degradation. PMID: 16878151
Biophysical characterization of the complex between human papillomavirus E6 protein and synapse-associated protein 97. PMID: 21113079
Escape of p53 protein from E6-mediated degradation in HeLa cells after cisplatin therapy. PMID: 12209989
Molecular insights into the interaction of HPV-16 E6 variants against MAGI-1 PDZ1 domain. PMID: 35115618
A family of proteins structurally and functionally related to the E6-AP ubiquitin-protein ligase. PMID: 7708685
Expression of human papillomavirus type 16 E6 protein by recombinant baculovirus and use for detection of anti-E6 antibodies in human sera. PMID: 1328490
The expression of human papillomavirus type 18 E6 protein in bacteria and the production of anti-E6 antibodies. PMID: 3018129
The E6 oncoproteins of high-risk papillomaviruses bind to a novel putative GAP protein, E6TP1, and target it for degradation. PMID: 9858596
Mechanism of HPV E6 proteins in cellular transformation. PMID: 9284524
A cellular protein mediates association of p53 with the E6 oncoprotein of human papillomavirus types 16 or 18. PMID: 1661671
The bovine papillomavirus E6 protein binds to the LD motif repeats of paxillin and blocks its interaction with vinculin and the focal adhesion kinase. PMID: 9407131
Interaction of papillomavirus E6 oncoproteins with a putative calcium-binding protein. PMID: 7624774
Molecular Probing of the HPV-16 E6 Protein Alpha Helix Binding Groove with Small Molecule Inhibitors. PMID: 26915086
Design and characterization of helical peptides that inhibit the E6 protein of papillomavirus. PMID: 15182185
The DNA repair protein, O(6)-methylguanine-DNA methyltransferase is a proteolytic target for the E6 human papillomavirus oncoprotein. PMID: 12185595
Stabilization of HPV16 E6 protein by PDZ proteins, and potential implications for genome maintenance. PMID: 21489588
For research use only. Not for human or drug use.
