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Recombinant Hepatitis B virus/HBV X/HBx Protein, N-His

Catalog #:   YVV05201 Specific References (118) DATASHEET
Applications: ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Expression system: E. coli
Accession: YP_009173867.1
Protein length: Ala2-Ala154
Overview

Catalog No.

YVV05201

Expression system

E. coli

Species

Hepatitis B virus (HBV)

Protein length

Ala2-Ala154

Predicted molecular weight

17.83 kDa

Nature

Recombinant

Endotoxin level

Please contact with the lab for this information.

Purity

>90% as determined by SDS-PAGE.

Accession

YP_009173867.1

Applications

ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress

Form

Lyophilized

Storage buffer

Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.

Reconstitution

Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.

Shipping

In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Alternative Names

Protein X, HBx, Peptide X, pX, X

Data Image
  • SDS-PAGE
    SDS PAGE for Recombinant Hepatitis B virus/HBV X/HBx Protein
References

Hepatitis B virus biology and life cycle. PMID: 32866519

Hepatitis B Virus. PMID: 29500037

Mechanisms of Hepatitis B Virus Persistence. PMID: 28823759

Hepatitis B virus: virology, molecular biology, life cycle and intrahepatic spread. PMID: 29098564

Gold nanoparticles and hepatitis B virus. PMID: 30686057

Hepatitis B virus replication. PMID: 8137119

Hepatitis B Virus X and Regulation of Viral Gene Expression. PMID: 26747833

Reactivation of hepatitis B virus in patients receiving chemotherapy. PMID: 23183929

Hepatitis B virus: origin and evolution. PMID: 20002567

Hepatitis B virus subgenotyping: history, effects of recombination, misclassifications, and corrections. PMID: 23538336

An overview of occult hepatitis B virus infection. PMID: 21528070

Possible origins and evolution of the hepatitis B virus (HBV). PMID: 24013024

Hepatitis B: virus, pathogenesis and treatment. PMID: 9915026

Hepatitis B virus in Pakistan: a systematic review of prevalence, risk factors, awareness status and genotypes. PMID: 21375760

Hepatitis B virus mutants: an overview. PMID: 12534785

Hepatitis B virus structure and biology. PMID: 2671579

Hepatitis B virus: pathogenesis, viral intermediates, and viral replication. PMID: 15481342

Hepatitis B virus genotype E variability in Africa. PMID: 18922739

Complete and Incomplete Hepatitis B Virus Particles: Formation, Function, and Application. PMID: 28335554

Role of the hepatitis B virus proteins in pro- and anti-apoptotic processes. PMID: 20036802

Hepatitis B virus: old, new and future approaches to antiviral treatment. PMID: 12654750

Discovery and optimization of benzenesulfonamides-based hepatitis B virus capsid modulators via contemporary medicinal chemistry strategies. PMID: 32949990

Control of hepatitis B virus replication by interferons and Toll-like receptor signaling pathways. PMID: 25206268

Antiviral therapy of decompensated hepatitis B virus-related cirrhosis. PMID: 22340574

Hepatitis B virus (HBV) DNA assays (methods and practical use) and viral kinetics. PMID: 14708675

Identifying and Characterizing Interplay between Hepatitis B Virus X Protein and Smc5/6. PMID: 28368357

Hepatitis B virus replication: novel roles for virus-host interactions. PMID: 10516465

Hysteresis in Hepatitis B Virus (HBV) Requires Assembly of Near-Perfect Capsids. PMID: 35258283

[From the Establishment of Hepatitis B Virus Cell Culture Systems to Drug Discovery]. PMID: 30606935

Dynamics of hepatitis B virus infection. PMID: 12270730

Hepatitis B virus screening and potential reactivation in patients undergoing treatment for cancer. PMID: 25505205

Taxonomic classification of human hepatitis B virus. PMID: 3516924

Genotypes and genetic variability of hepatitis B virus. PMID: 25034481

Tenofovir disoproxil fumarate for prevention of mother-to-child transmission of hepatitis B virus: A systematic review and meta-analysis of randomised control trials. PMID: 33483986

Molecular genotyping of hepatitis B virus. PMID: 12467776

Phage display creates innovative applications to combat hepatitis B virus. PMID: 25206271

Molecular biology of the hepatitis B virus and role of the X gene. PMID: 20483545

Bacteriophages and their applications in the diagnosis and treatment of hepatitis B virus infection. PMID: 25206272

The molecular biology of hepatitis B virus. PMID: 2547259

Biological features of hepatitis B virus isolates from patients based on full-length genomic analysis. PMID: 19058172

Identification of hepatitis B virus genotype I in Thailand. PMID: 30351478

Hepatitis B virus genetic typing using mass-spectrometry. PMID: 19513426

Clinical virology of hepatitis B virus infection. PMID: 14708674

Using proteomics to identify the HBx interactome in hepatitis B virus: how can this inform the clinic? PMID: 24308553

HBV virological assessment. PMID: 16343681

Discovery of Novel Hepatitis B Virus Nucleocapsid Assembly Inhibitors. PMID: 30525438

Therapy of chronic hepatitis B virus infection: inhibition of the viral polymerase and other antiviral strategies. PMID: 10588330

Molecular mechanism of capsid disassembly in hepatitis B virus. PMID: 34465620

[Recent Advances in Hepatitis B Virus Antivirals]. PMID: 30004193

Antiviral therapy for hepatitis B virus infections: new targets and technical challenges. PMID: 12423691

High tolerance of hepatitis B virus to thermal disinfection. PMID: 31493444

Identification of hepatitis B virus genotype A/E recombinants in Ghana. PMID: 31346975

[Hepatitis B virus reactivation induced by Brentuximab vedotin in the treatment of Hodgkin lymphoma: a case report and literature review]. PMID: 25339337

Host and tissue tropism of hepatitis B virus. PMID: 1619982

Fitness and infectivity of drug-resistant and cross-resistant hepatitis B virus mutants: why and how is it studied? PMID: 20516574

Interferon Alpha Induces Cellular Autophagy and Modulates Hepatitis B Virus Replication. PMID: 35186790

Hepatitis B virus resistance substitutions: long-term analysis by next-generation sequencing. PMID: 27447462

Evolution of Intermediates during Capsid Assembly of Hepatitis B Virus with Phenylpropenamide-Based Antivirals. PMID: 30616343

Resistance of human hepatitis B virus to reverse transcriptase inhibitors: from genotypic to phenotypic testing. PMID: 16461221

[Hepatitis B virus (HBV) replication in animal models and their applications]. PMID: 22096945

[Progress in research of occult hepatitis B virus infection]. PMID: 28651413

Influence of mutations in the hepatitis B virus genome on virus replication and drug resistance--implications for novel antiviral strategies. PMID: 15544468

Heterogeneous recombination among Hepatitis B virus genotypes. PMID: 28827173

Genetic variability of hepatitis B virus and response to antiviral therapy. PMID: 18771045

Conformational Dynamics of the Hepatitis B Virus Pre-genomic RNA on Multiple Time Scales: Implications for Viral Replication. PMID: 35595167

Structural insights of the conserved "priming loop" of hepatitis B virus pre-genomic RNA. PMID: 34155954

Organ and species specificity of hepatitis B virus (HBV) infection: a review of literature with a special reference to preferential attachment of HBV to human hepatocytes. PMID: 9181523

Characterization of hepatitis B virus with complex structural variations. PMID: 30509169

Structural basis of the hepatitis B virus X protein in complex with DDB1., PMID:40512786

Lamin A/C promotes HBV transcription by modulating histone modification associated with cccDNA minichromosome in an HBx-dependent manner., PMID:40500754

Hepatitis B Virus X Protein Upregulates SREBP2 to Modulate Autophagy in Hepatocellular Carcinoma., PMID:40476478

Comparative structural insights of X protein across species and the "lost" BH3-like domain that may explain the absence of hepatocellular carcinoma in birds., PMID:40472953

Transcriptional regulation of tumor suppressor gene RASSF1A by HBx., PMID:40419121

The Intrinsically Disordered Region of HBx and Virus-Host Interactions: Uncovering New Therapeutic Approaches for HBV and Cancer., PMID:40332052

Hepatitis B Virus Disrupts the Blood-Testis Barrier via the Induction of mTOR-Dependent Autophagy in Sertoli Cells., PMID:40266246

HBx/WDR5 enhances IGF-1 transcription in hepatocellular carcinoma cells and promotes recruitment, infiltration, and activity of Treg cells., PMID:40199768

HBx/DTL Positive Feedback Loop Promotes HBV-Related Hepatocellular Carcinoma Progression., PMID:40062428

HBX Multi-Mutations Combined With Traditional Screening Indicators to Establish a Nomogram Contributes to Precisely Stratify the High-Risk Population of Hepatocellular Carcinoma., PMID:40042093

IL35 modulates HBV-related HCC progression via IL6-STAT3 signaling., PMID:39984567

A nucleosome switch primes hepatitis B virus infection., PMID:39983728

Long-term inhibition of Hepatitis B virus gene expression by a primary microrna expressing ancestral adeno-associated viral vector., PMID:39962472

ALR inhibits HBV replication and autophagosome formation by ameliorating HBV-induced ROS production in hepatic cells., PMID:39934594

Protein regulator of cytokinesis 1 regulates autophagy in hepatitis B virus‑associated liver cancer development., PMID:39930820

HBx protein as a therapeutic target for functional cure of hepatitis B virus infection., PMID:39908774

Hepatitis B Virus X Protein promotes VWF-mediated HCC progression through ST8SIA6-AS1/miR-3150b-3p/ASCL1 axis., PMID:39884328

Homeobox protein MSX-1 restricts hepatitis B virus by promoting ubiquitin-independent proteasomal degradation of HBx protein., PMID:39883729

Cholesterol metabolism regulator SREBP2 inhibits HBV replication via suppression of HBx nuclear translocation., PMID:39872518

Correction: Zhang et al. Hepatitis B Virus X Protein (HBx) Suppresses Transcription Factor EB (TFEB) Resulting in Stabilization of Integrin Beta 1 (ITGB1) in Hepatocellular Carcinoma Cells. Cancers 2021, 13, 1181., PMID:39796790

Hepatitis B virus genotypes A1 and A2 have distinct replication phenotypes due to polymorphisms in the HBx gene., PMID:39787208

HBV Remodels PP2A Complexes to Rewire Kinase Signaling in Hepatocellular Carcinoma., PMID:39652575

Molecular Biological Mechanisms of Action of Chrysophanol in Hepatic Stellate Cells Activated by Hepatic B Virus X Based on Network Pharmacology., PMID:39647471

Design of multi-epitope-based therapeutic vaccine candidates from HBc and HBx proteins of hepatitis B virus using reverse vaccinology and immunoinformatics approaches., PMID:39642099

KIF20A activated by transcription factor GATA2 promotes cell growth in hepatitis B virus-related hepatocellular carcinoma., PMID:39624268

SMC5/6-Mediated Transcriptional Regulation of Hepatitis B Virus and Its Therapeutic Potential., PMID:39599784

LncRNA MALAT1 promotes Erastin-induced ferroptosis in the HBV-infected diffuse large B-cell lymphoma., PMID:39532842

Insight into the mechanisms regulating liver cancer stem cells by hepatitis B virus X protein., PMID:39529119

Identification and characterization of host factor VCPIP1 as a multi-functional positive regulator of hepatitis B virus., PMID:39494904

Hidden liver-joint axis: HBV infection causes rheumatoid arthritis via TRAFD1 with imbalance of HBV X protein and trans-ferulic acid., PMID:39484999

Asiatic acid inhibits HBV cccDNA transcription by promoting HBx degradation., PMID:39468627

Hepatitis B Virus X Protein Induces Reactive Oxygen Species Generation via Activation of p53 in Human Hepatoma Cells., PMID:39456134

Hepatitis B Virus X Protein Contributes to Hepatocellular Carcinoma via Upregulation of KIAA1429 Methyltransferase and mRNA m6A Hypermethylation of HSPG2/Perlecan., PMID:39412412

The dual-specificity kinase DYRK1A interacts with the Hepatitis B virus genome and regulates the production of viral RNA., PMID:39405283

HBx-induced upregulation of MAP1S drives hepatocellular carcinoma proliferation and migration via MAP1S/Smad/TGF-β1 loop., PMID:39374711

Hepatitis B Viral Protein HBx: Roles in Viral Replication and Hepatocarcinogenesis., PMID:39339838

USP26 as a hepatitis B virus-induced deubiquitinase primes hepatocellular carcinogenesis by epigenetic remodeling., PMID:39251623

Hepatitis B virus X protein differentially regulates the angiogenesis of Hepatocellular Carcinoma through p53-VEGF axis according to glucose levels., PMID:39216627

Hepatitis B Virus X Protein Induces Expression Changes of miR-21, miR-22, miR-122, miR-132, and miR-222 in Huh-7 Cell Line., PMID:39192965

Targeting TGR5 to mitigate liver fibrosis: Inhibition of hepatic stellate cell activation through modulation of mitochondrial fission., PMID:39111149

SOD1 inhibition enhances sorafenib efficacy in HBV-related hepatocellular carcinoma by modulating PI3K/Akt/mTOR pathway and ROS-mediated cell death., PMID:39034442

HBx integration in diffuse large B-cell lymphoma inhibits Caspase-3-PARP related apoptosis., PMID:39032828

SIGIRR suppresses hepatitis B virus X protein-induced chronic inflammation in hepatocytes., PMID:39013482

The nuclear matrix protein HNRNPU restricts hepatitis B virus transcription by promoting OAS3-based activation of host innate immunity., PMID:39011773

HBx promotes glomerular podocyte-induced immune cell responses., PMID:38967134

Hepatitis B virus X protein and TGF-β: partners in the carcinogenic journey of hepatocellular carcinoma., PMID:38962270

Reactive Oxygen Species Induction by Hepatitis B Virus: Implications for Viral Replication in p53-Positive Human Hepatoma Cells., PMID:38928309

Hemodialysis bilayer bionic blood vessels developed by the mechanical stimulation of hepatitis B viral X(HBX) gene- transfected hepatic stellate cells., PMID:38910495

All-trans retinoic acid downregulates HBx levels via E6-associated protein-mediated proteasomal degradation to suppress hepatitis B virus replication., PMID:38861553

SIAH2 suppresses c-JUN pathway by promoting the polyubiquitination and degradation of HBx in hepatocellular carcinoma., PMID:38842124

Datasheet
$ 313
Product specifications
100 μg 313 1 mg 1629

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Recombinant Hepatitis B virus/HBV X/HBx Protein, N-His [YVV05201]
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