Catalog No.
YVV11801
Expression system
E. coli
Species
Human papillomavirus type 18
Protein length
Val82-Gly535
Predicted molecular weight
78.56 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P06794
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Major capsid protein L1, L1
Human Papillomavirus Vaccines. PMID: 34590141
Prophylactic HPV vaccination: past, present, and future. PMID: 26429676
Treatment with Radix Euphorbiae Ebracteolatae Significantly Decreases the Expression of E6 and L1, and Increases the Expression of p53 and Rb in HPV18-infected Human Foreskin Keratinocytes. PMID: 30813877
Can a single dose of human papillomavirus (HPV) vaccine prevent cervical cancer? Early findings from an Indian study. PMID: 29551226
Efficacy of the bivalent HPV vaccine against HPV 16/18-associated precancer: long-term follow-up results from the Costa Rica Vaccine Trial. PMID: 33271093
Phylogeny and Classification of Human Papillomavirus (HPV)16 and HPV18 Variants Based on E6 and L1 genes in Tunisian Women with Cervical Lesions. PMID: 30583341
Glutathione S-transferase L1 multiplex serology as a measure of cumulative infection with human papillomavirus. PMID: 24588945
Development and characterization of an HPV18 detection kit using two novel HPV18 type-specific monoclonal antibodies. PMID: 30115088
Worldwide genetic variations in high-risk human papillomaviruses capsid L1 gene and their impact on vaccine efficiency. PMID: 33636291
Immunotherapy Targeting HPV16/18 Generates Potent Immune Responses in HPV-Associated Head and Neck Cancer. PMID: 30242022
Study of infectious virus production from HPV18/16 capsid chimeras. PMID: 20598725
PD-L1 expressed from tumor cells promotes tumor growth and invasion in lung cancer via modulating TGF-β1/SMAD4 expression. PMID: 35373505
A ten-year study of immunogenicity and safety of the AS04-HPV-16/18 vaccine in adolescent girls aged 10-14 years. PMID: 31268383
A comparison of methylation levels in HPV18, HPV31 and HPV33 genomes reveals similar associations with cervical precancers. PMID: 24468012
Controlled Hybrid-Assembly of HPV16/18 L1 Bi VLPs in Vitro. PMID: 27998118
The Effect of Indian Fig Fruit Extract on Human Papilloma Virus containing Cervical Cancer Cells (HeLa) by Decreasing the HPV18 L1 Gene Load. PMID: 33773542
Human papillomavirus (HPV) L1 and L1-L2 virus-like particle-based multiplex assays for measurement of HPV virion antibodies. PMID: 22761294
Multivalent human papillomavirus l1 DNA vaccination utilizing electroporation. PMID: 23536912
HPV vaccine: Cervarix. PMID: 20132062
The Synthesis of Main Capsid Protein of Anogenital Type HPV6 L1 in Plant Expression System on the Basis of Tomato Fruits. PMID: 34189649
[Human papillomavirus vaccines]. PMID: 18187268
Genetic Variability in the E6, E7, and L1 Genes of Human Papillomavirus Types 16 and 18 among Women in Saudi Arabia. PMID: 36680149
Fifteen new nucleotide substitutions in variants of human papillomavirus 18 in Korea : Korean HPV18 variants and clinical manifestation. PMID: 32448303
A cyclin-binding motif in human papillomavirus type 18 (HPV18) E1^E4 is necessary for association with CDK-cyclin complexes and G2/M cell cycle arrest of keratinocytes, but is not required for differentiation-dependent viral genome amplification or L1 capsid protein expression. PMID: 21276999
Enhanced expression of soluble human papillomavirus L1 through coexpression of molecular chaperonin in Escherichia coli. PMID: 26732286
Identification of the mimotopes within the major capsid protein L1 of human papillomavirus types 18 and 45, using neutralizing monoclonal antibodies. PMID: 33493568
L1 Recombinant Proteins of HPV Tested for Antibody Forming Using Sera of HPV Quadrivalent Vaccine. PMID: 29984037
Aberrant DNA methylation in cervical carcinogenesis. PMID: 22943599
Sex differences in HPV immunity among adults without cancer. PMID: 30650013
HPV single-dose vaccination: Impact potential, evidence base and further evaluation. PMID: 29754700
The Prognostic Values of HPV Genotypes and Tumor PD-L1 Expression in Patients With HPV-associated Endocervical Adenocarcinoma. PMID: 35175967
Immunogenicity assessment of HPV16/18 vaccine using the glutathione S-transferase L1 multiplex serology assay. PMID: 25483632
Development of chimeric candidate vaccine against HPV18: a proof of concept. PMID: 25929429
Expression and purification of human papillomavirus 18 L1 virus-like particle from saccharomyces cerevisiae. PMID: 18365691
Prophylactic human papillomavirus vaccines. PMID: 16670757
The First Human Vulvar Intraepithelial Neoplasia Cell Line with Naturally Infected Episomal HPV18 Genome. PMID: 36146860
Characteristics of human papillomavirus infection among females and the genetic variations of HPV18 and HPV58 in Henan province, China. PMID: 36755053
A phase I study to evaluate a human papillomavirus (HPV) type 18 L1 VLP vaccine. PMID: 15297048
Methylation of the L1 gene and integration of human papillomavirus 16 and 18 in cervical carcinoma and premalignant lesions. PMID: 29434935
Liquid biopsy of HPV DNA in cervical cancer. PMID: 30913520
Epitope design of L1 protein for vaccine production against Human Papilloma Virus types 16 and 18. PMID: 28584449
Utility of human papillomavirus L1 capsid protein and HPV test as prognostic markers for cervical intraepithelial neoplasia 2+ in women with persistent ASCUS /LSIL cervical cytology. PMID: 31523171
Broad Cross-Protection Is Induced in Preclinical Models by a Human Papillomavirus Vaccine Composed of L1/L2 Chimeric Virus-Like Particles. PMID: 27147749
For research use only. Not for human or drug use.
