Catalog No.
RHH39201
Species reactivity
Human
Host species
Mouse
Isotype
IgG2a, kappa
Clonality
Monoclonal
Target
Membrane primary amine oxidase, AOC3, SSAO, Semicarbazide-sensitive amine oxidase, Vascular adhesion protein 1, VAP-1, HPAO, Copper amine oxidase, VAP1
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q16853
Applications
ELISA, FCM, IF, IHC, IP, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
TK8-14
Vascular adhesion protein-1 blockade in primary sclerosing cholangitis: Open-label, multicenter, single-arm, phase II trial., PMID:38668724
Vascular adhesion protein-1 expression is reduced in the intestines of infants with necrotizing enterocolitis: an observational research study., PMID:36335313
Vascular adhesion protein-1 (VAP-1) in vascular inflammatory diseases., PMID:36200383
The Use of Biologics in Patients with Inflammatory Bowel Disease and Primary Sclerosing Cholangitis., PMID:31008013
Vascular Adhesion Protein-1: A Cell Surface Amine Oxidase in Translation., PMID:29065711
Soluble Vascular Adhesion Protein-1 Mediates Spermine Oxidation as Semicarbazide-Sensitive Amine Oxidase: Possible Role in Proliferative Diabetic Retinopathy., PMID:28937866
Investigating the safety and activity of the use of BTT1023 (Timolumab), in the treatment of patients with primary sclerosing cholangitis (BUTEO): A single-arm, two-stage, open-label, multi-centre, phase II clinical trial protocol., PMID:28674140
Feasibility of (68)Ga-labeled Siglec-9 peptide for the imaging of acute lung inflammation: a pilot study in a porcine model of acute respiratory distress syndrome., PMID:27069763
Myofibroblasts are distinguished from activated skin fibroblasts by the expression of AOC3 and other associated markers., PMID:27036009
Evaluation of serum and tissue levels of VAP-1 in colorectal cancer., PMID:26912327
68Ga-DOTA-Siglec-9--a new imaging tool to detect synovitis., PMID:26530096
VAP-1 blockade prevents subarachnoid hemorrhage-associated cerebrovascular dilating dysfunction via repression of a neutrophil recruitment-related mechanism., PMID:25662771
Ligand-dependent localization and function of ORP-VAP complexes at membrane contact sites., PMID:25420878
The oxidase activity of vascular adhesion protein-1 (VAP-1) is essential for function., PMID:23885334
Preclinical evaluation of a radioiodinated fully human antibody for in vivo imaging of vascular adhesion protein-1-positive vasculature in inflammation., PMID:23847292
Identification, prioritization, and evaluation of glycoproteins for aggressive prostate cancer using quantitative glycoproteomics and antibody-based assays on tissue specimens., PMID:23716368
Therapeutic advantage of anti-VAP-1 over anti-α4 integrin antibody in concanavalin a-induced hepatitis., PMID:23686782
Adhesion molecules in CNS disorders: biomarker and therapeutic targets., PMID:23469854
VCAM-1 and VAP-1 recruit myeloid cells that promote pulmonary metastasis in mice., PMID:23407548
Lack of association between VAP-1/SSAO activity and corneal neovascularization in a rabbit model., PMID:23397320
The untapped potential of Gallium 68-PET: the next wave of ⁶⁸Ga-agents., PMID:23232184
CXCR3-dependent recruitment and CCR6-mediated positioning of Th-17 cells in the inflamed liver., PMID:22796894
Immunolocalization of vascular adhesion protein-1 in human conjunctival tumors., PMID:22354146
Semicarbazide-sensitive amine oxidase/vascular adhesion protein-1: a patent survey., PMID:21675926
Preliminary studies of the effects of vascular adhesion protein-1 inhibitors on experimental corneal neovascularization., PMID:21331460
Regulation of mucosal addressin cell adhesion molecule 1 expression in human and mice by vascular adhesion protein 1 amine oxidase activity., PMID:21225644
Small-molecule inhibitors of vascular adhesion protein-1 reduce the accumulation of myeloid cells into tumors and attenuate tumor growth in mice., PMID:20154208
Localization of vascular adhesion protein-1 (VAP-1) in the human eye., PMID:19761765
Ischemia-reperfusion injury is attenuated in VAP-1-deficient mice and by VAP-1 inhibitors., PMID:18991279
VAP-1-deficient mice display defects in mucosal immunity and antimicrobial responses: implications for antiadhesive applications., PMID:17947691
Anti endothelial cell autoantibodies selectively activate SAPK/JNK signalling in Wegener's granulomatosis., PMID:17699811
Early intrahepatic antigen-specific retention of naïve CD8+ T cells is predominantly ICAM-1/LFA-1 dependent in mice., PMID:16250049
Function-blocking antibodies to human vascular adhesion protein-1: a potential anti-inflammatory therapy., PMID:16224816
Rules of recruitment for Th1 and Th2 lymphocytes in inflamed liver: a role for alpha-4 integrin and vascular adhesion protein-1., PMID:16111634
[Vascular adhesion protein-1: an unusual adhesion molecule]., PMID:15928600
Safety of blocking vascular adhesion protein-1 in patients with contact dermatitis., PMID:15910406
Vascular adhesion protein-1 is involved in both acute and chronic inflammation in the mouse., PMID:15743791
Blockade of vascular adhesion protein-1 inhibits lymphocyte infiltration in rat liver allograft rejection., PMID:15579442
Granulocyte transmigration through the endothelium is regulated by the oxidase activity of vascular adhesion protein-1 (VAP-1)., PMID:14726375
Characterization of vascular adhesion molecules that may facilitate progenitor homing in the post-natal mouse thymus., PMID:14575155
Expression of vascular adhesion protein-1 in normal and inflamed mice lungs and normal human lungs., PMID:12700900
[Concentration of sVAP in serum of patients with different forms of Lyme borreliosis]., PMID:12194234
Characterization of the inflammatory infiltrate and expression of endothelial cell adhesion molecules in lupus erythematosus tumidus., PMID:12071156
Inflammation, immune reactivity, and angiogenesis in a severe combined immunodeficiency model of rheumatoid arthritis., PMID:11786429
Mechanisms of T-cell homing to skin., PMID:11758117
A cell surface amine oxidase directly controls lymphocyte migration., PMID:11290336
Human leukocyte subpopulations from inflamed gut bind to joint vasculature using distinct sets of adhesion molecules., PMID:11254724
Vascular adhesion protein 1 (VAP-1) functions as a molecular brake during granulocyte rolling and mediates recruitment in vivo., PMID:11156953
Induction of vascular adhesion protein-1 during liver allograft rejection and concomitant cytomegalovirus infection in rats., PMID:11021827
For research use only. Not for human or drug use.
