Catalog No.
PHA67901
Species reactivity
Human, Mouse
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human SUV39H1 (Gly7-Met271).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Position-effect variegation 3-9 homolog,SUV39H,H3-K9-HMTase 1,SUV39H1,Histone-lysine N-methyltransferase SUV39H1,Su(var)3-9 homolog 1,Lysine N-methyltransferase 1A,Histone H3-K9 methyltransferase 1,Suppressor of variegation 3-9 homolog 1,KMT1A
Purification
Purified by antigen affinity column.
Accession
O43463
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Human endogenous retroviruses as epigenetic therapeutic targets in TP53-mutated diffuse large B-cell lymphoma., PMID:37798292
Spatial Multiplexed Protein Profiling of Cardiac Ischemia-Reperfusion Injury., PMID:37249015
PHF6 functions as a tumor suppressor by recruiting methyltransferase SUV39H1 to nucleolar region and offers a novel therapeutic target for PHF6-muntant leukemia., PMID:35847518
Alcoholic hepatitis versus non-alcoholic steatohepatitis: Levels of expression of some proteins involved in tumorigenesis., PMID:29307797
High Glucose Increases the Expression of Inflammatory Cytokine Genes in Macrophages Through H3K9 Methyltransferase Mechanism., PMID:26406561
PDT-induced epigenetic changes in the mouse cerebral cortex: a protein microarray study., PMID:24055374
Non-radioactive protein lysine methyltransferase microplate assay based on reading domains., PMID:23671032
Methylation of SUV39H1 by SET7/9 results in heterochromatin relaxation and genome instability., PMID:23509280
Inhibition of p53 DNA binding function by the MDM2 protein acidic domain., PMID:21454483
RFX1 regulates CD70 and CD11a expression in lupus T cells by recruiting the histone methyltransferase SUV39H1., PMID:21192791
CLLD8/KMT1F is a lysine methyltransferase that is important for chromosome segregation., PMID:20404330
Epigenetic modifications and related mRNA expression during bovine oocyte in vitro maturation., PMID:19567217
The impact of heterochromatin on DSB repair., PMID:19442252
KRAB zinc-finger proteins localise to novel KAP1-containing foci that are adjacent to PML nuclear bodies., PMID:19258395
PRC1 and Suv39h specify parental asymmetry at constitutive heterochromatin in early mouse embryos., PMID:18311137
The histone methyltransferase Suv39h1 increases class switch recombination specifically to IgA., PMID:16818776
Differential subnuclear localization and replication timing of histone H3 lysine 9 methylation states., PMID:15788566
Histone methyltransferases direct different degrees of methylation to define distinct chromatin domains., PMID:14690610
Partitioning and plasticity of repressive histone methylation states in mammalian chromatin., PMID:14690609
Suv39h-mediated histone H3 lysine 9 methylation directs DNA methylation to major satellite repeats at pericentric heterochromatin., PMID:12867029
Histone H3 lysine 4 methylation is mediated by Set1 and required for cell growth and rDNA silencing in Saccharomyces cerevisiae., PMID:11751634
For research use only. Not for human or drug use.
