Catalog No.
RVV15104
Species reactivity
Epstein-Barr virus (strain B95-8) (HHV-4) (Human herpesvirus 4), Epstein-Barr virus (strain GD1) (HHV-4) (Human herpesvirus 4)
Host species
Human
Isotype
IgG1, kappa
Clonality
Monoclonal
Target
Envelope glycoprotein H, gH, BXLF2
Concentration
4.37 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P03231, K9US75
Applications
ELISA, FCM, SPR
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
AMMO1
Neutralizing Antibodies Protect against Oral Transmission of Lymphocryptovirus. PMID: 32724901
Immunization with a self-assembling nanoparticle vaccine displaying EBV gH/gL protects humanized mice against lethal viral challenge. PMID: 35705092
An Antibody Targeting the Fusion Machinery Neutralizes Dual-Tropic Infection and Defines a Site of Vulnerability on Epstein-Barr Virus. PMID: 29669253
gH/gL supercomplexes at early stages of herpesvirus entry. PMID: 26849495
The Human Cytomegalovirus Protein UL116 Interacts with the Viral Endoplasmic-Reticulum-Resident Glycoprotein UL148 and Promotes the Incorporation of gH/gL Complexes into Virions. PMID: 34011552
Non-redundant and redundant roles of cytomegalovirus gH/gL complexes in host organ entry and intra-tissue spread. PMID: 25659098
Structural and biochemical studies of HCMV gH/gL/gO and Pentamer reveal mutually exclusive cell entry complexes. PMID: 25624487
Mutagenesis of Human Cytomegalovirus Glycoprotein L Disproportionately Disrupts gH/gL/gO over gH/gL/pUL128-131. PMID: 34132577
Human cytomegalovirus glycoprotein gO complexes with gH/gL, promoting interference with viral entry into human fibroblasts but not entry into epithelial cells. PMID: 21880752
Antigenic Characterization of the HCMV gH/gL/gO and Pentamer Cell Entry Complexes Reveals Binding Sites for Potently Neutralizing Human Antibodies. PMID: 26485028
Functional analysis of glycoprotein L (gL) from rhesus lymphocryptovirus in Epstein-Barr virus-mediated cell fusion indicates a direct role of gL in gB-induced membrane fusion. PMID: 19457993
A viral regulator of glycoprotein complexes contributes to human cytomegalovirus cell tropism. PMID: 25831500
Pathogen at the Gates: Human Cytomegalovirus Entry and Cell Tropism. PMID: 30544948
Human Cytomegalovirus gH/gL Forms a Stable Complex with the Fusion Protein gB in Virions. PMID: 27082872
Scanning Mutagenesis of Human Cytomegalovirus Glycoprotein gH/gL. PMID: 26656708
Characterization of the human cytomegalovirus gH/gL/UL128-131 complex that mediates entry into epithelial and endothelial cells. PMID: 17942555
Expression Levels of Glycoprotein O (gO) Vary between Strains of Human Cytomegalovirus, Influencing the Assembly of gH/gL Complexes and Virion Infectivity. PMID: 29743375
Human cytomegalovirus glycoprotein complex gH/gL/gO uses PDGFR-α as a key for entry. PMID: 28403202
Entry of betaherpesviruses. PMID: 31439151
Soluble Epstein-Barr virus glycoproteins gH, gL, and gp42 form a 1:1:1 stable complex that acts like soluble gp42 in B-cell fusion but not in epithelial cell fusion. PMID: 16973550
Human cytomegalovirus gH/gL/UL128/UL130/UL131A complex elicits potently neutralizing antibodies in mice. PMID: 24837507
Principles for studying in vivo attenuation of virus mutants: defining the role of the cytomegalovirus gH/gL/gO complex as a paradigm. PMID: 25782576
Herpes simplex virus gD forms distinct complexes with fusion executors gB and gH/gL in part through the C-terminal profusion domain. PMID: 19386594
Epstein-Barr virus uses different complexes of glycoproteins gH and gL to infect B lymphocytes and epithelial cells. PMID: 9621012
The Human Cytomegalovirus UL116 Gene Encodes an Envelope Glycoprotein Forming a Complex with gH Independently from gL. PMID: 26937030
Human Cytomegalovirus gH/gL/gO Promotes the Fusion Step of Entry into All Cell Types, whereas gH/gL/UL128-131 Broadens Virus Tropism through a Distinct Mechanism. PMID: 26085146
Formation and characteristics of alginate and anthocyanin complexes. PMID: 32698067
A Viral Pilot for HCMV Navigation? PMID: 26184287
Role of fibronectin on the clearance and tissue uptake of antigen and immune complexes in rats. PMID: 3316274
Herpes Simplex Virus 1 Entry Glycoproteins Form Complexes before and during Membrane Fusion. PMID: 35972147
Expression and reconstitution of the gH/gL/gO complex of human cytomegalovirus. PMID: 12361760
Guinea pig cytomegalovirus trimer complex gH/gL/gO uses PDGFRA as universal receptor for cell fusion and entry. PMID: 32791352
Protein-polysaccharide complexes as surfactants. PMID: 3748120
For research use only. Not for human or drug use.
