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Anti-EBV/HHV-4 gH/BXLF2 Antibody (CL40)

Catalog #:   RVV15101 Specific References (65) DATASHEET
Host species: Human
Isotype: IgG1, kappa
Applications: ELISA, Neutralization
Accession: P03231, K9US75
Overview

Catalog No.

RVV15101

Species reactivity

Epstein-Barr virus (strain B95-8) (HHV-4) (Human herpesvirus 4), Epstein-Barr virus (strain GD1) (HHV-4) (Human herpesvirus 4)

Host species

Human

Isotype

IgG1, kappa

Clonality

Monoclonal

Target

Envelope glycoprotein H, gH, BXLF2,gHgL

Concentration

2.28 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P03231, K9US75

Applications

ELISA, Neutralization

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

CL40

Data Image
  • SDS-PAGE
    SDS PAGE for EBV/HHV-4 gH/BXLF2 Antibody (CL40)
  • SEC-HPLC
    The purity of this product is >95% as determined by SEC-HPLC.
References

Complementary Role of GlcNAc6ST2 and GlcNAc6ST3 in Synthesis of CL40-Reactive Sialylated and Sulfated Glycans in the Mouse Pleural Mesothelium. PMID: 35889417

Association of Emerging β-Amyloid and Tau Pathology With Early Cognitive Changes in Clinically Normal Older Adults. PMID: 35338074

Inhibition of EBV-mediated membrane fusion by anti-gHgL antibodies. PMID: 28939750

Functional contributions of N- and O-glycans to L-selectin ligands in murine and human lymphoid organs. PMID: 21224079

LncRNA MALAT1 promotes colorectal cancer development by sponging miR-363-3p to regulate EZH2 expression. PMID: 30972996

In vitro evaluation of biodegradable epsilon-caprolactone-co-D, L-lactide/silica xerogel composites containing toremifene citrate. PMID: 10370214

Induction of VCAM-1 and ICAM-1 on human neural cells and mechanisms of mononuclear leukocyte adherence. PMID: 1374096

Structure and function of plasmid pColD157 of enterohemorrhagic Escherichia coli O157 and its distribution among strains from patients with diarrhea and hemolytic-uremic syndrome. PMID: 9431914

A convergent synthetic platform for polymeric nanoparticle for the treatment of combination colorectal cancer therapy. PMID: 34121628

Untargeted metabolism approach reveals difference of varieties of bud and relation among characteristics of grafting seedlings in Camellia oleifera. PMID: 36479510

Characterization of three chicken pseudogenes for U1 RNA. PMID: 6207998

Identification of cell lines CL-14, CL-40 and CAL-51 as suitable models for SARS-CoV-2 infection studies. PMID: 34339474

Effect of endogenous multidrug resistance 1 and P-glycoprotein expression on anticancer drug resistance in colon cancer cell lines. PMID: 30556139

Comparison of the Effects of Clofibrate and Silafibrate on Sperm Parameters Quality and Sex Hormones in Male Rats. PMID: 29299890

A systematic approach for testing expression of human full-length proteins in cell-free expression systems. PMID: 17915018

Eph Receptor Tyrosine Kinases Are Functional Entry Receptors for Murine Gammaherpesvirus 68., PMID:40501621

A Liposome-Based Nanoparticle Vaccine Induces Effective Immunity Against EBV Infection., PMID:40338258

High IgG titers against EBV glycoprotein 42 correlate with lower risk of nasopharyngeal carcinoma., PMID:39959976

In-depth analysis of serum antibodies against Epstein-Barr virus lifecycle proteins, and EBNA1, ANO2, GlialCAM and CRYAB peptides in patients with multiple sclerosis., PMID:39742283

TianTan vaccinia virus-based EBV vaccines targeting both latent and lytic antigens elicits potent immunity against lethal EBV challenge in humanized mice., PMID:39387189

Association Between Antibodies That Bind Epstein-Barr Virus (EBV) gp350 and gH/gL and Shedding of EBV in Saliva From Nasopharyngeal Carcinoma Multiplex Family Members in Taiwan., PMID:39229285

GB and gH/gL fusion machinery: a promising target for vaccines to prevent Epstein-Barr virus infection., PMID:39020055

A gH/gL-encoding replicon vaccine elicits neutralizing antibodies that protect humanized mice against EBV challenge., PMID:38926438

Vaccination with nanoparticles displaying gH/gL from Epstein-Barr virus elicits limited cross-protection against rhesus lymphocryptovirus., PMID:38781964

Epstein-Barr virus gp42 antibodies reveal sites of vulnerability for receptor binding and fusion to B cells., PMID:38479361

Epstein-Barr Virus Glycoprotein Antibody Titers and Risk of Nasopharyngeal Carcinoma., PMID:36519117

Urgency and necessity of Epstein-Barr virus prophylactic vaccines., PMID:36494369

Epstein-Barr virus gH/gL has multiple sites of vulnerability for virus neutralization and fusion inhibition., PMID:36306784

Immunization with a self-assembling nanoparticle vaccine displaying EBV gH/gL protects humanized mice against lethal viral challenge., PMID:35705092

A novel high throughput assay to quantify Epstein-Barr virus neutralizing antibody activity against B-cell and epithelial cell infections for vaccine and therapeutic developments., PMID:35577627

A bivalent Epstein-Barr virus vaccine induces neutralizing antibodies that block infection and confer immunity in humanized mice., PMID:35507671

Four Decades of Prophylactic EBV Vaccine Research: A Systematic Review and Historical Perspective., PMID:35493498

A Neutralizing Antibody Targeting gH Provides Potent Protection against EBV Challenge In Vivo., PMID:35348362

Antibody Generation and Immunogenicity Analysis of EBV gp42 N-Terminal Region., PMID:34960650

A potent and protective human neutralizing antibody targeting a novel vulnerable site of Epstein-Barr virus., PMID:34785638

Epstein Barr Virus: Development of Vaccines and Immune Cell Therapy for EBV-Associated Diseases., PMID:34691042

Immunization with Epstein-Barr Virus Core Fusion Machinery Envelope Proteins Elicit High Titers of Neutralizing Activities and Protect Humanized Mice from Lethal Dose EBV Challenge., PMID:33808755

Association between Antibody Responses to Epstein-Barr Virus Glycoproteins, Neutralization of Infectivity, and the Risk of Nasopharyngeal Carcinoma., PMID:33268566

Maternal Epstein-Barr Virus-Specific Antibodies and Risk of Infection in Ugandan Infants., PMID:33095855

A Pentavalent Epstein-Barr Virus-Like Particle Vaccine Elicits High Titers of Neutralizing Antibodies against Epstein-Barr Virus Infection in Immunized Rabbits., PMID:32268575

EBNA1 IgM-Based Discrimination Between Rheumatoid Arthritis Patients, Systemic Lupus Erythematosus Patients and Healthy Controls., PMID:31544841

Identification of multiple potent neutralizing and non-neutralizing antibodies against Epstein-Barr virus gp350 protein with potential for clinical application and as reagents for mapping immunodominant epitopes., PMID:31377598

Immunization with Components of the Viral Fusion Apparatus Elicits Antibodies That Neutralize Epstein-Barr Virus in B Cells and Epithelial Cells., PMID:30979688

An Antibody Targeting the Fusion Machinery Neutralizes Dual-Tropic Infection and Defines a Site of Vulnerability on Epstein-Barr Virus., PMID:29669253

Antibodies to a strain-specific citrullinated Epstein-Barr virus peptide diagnoses rheumatoid arthritis., PMID:29487382

Ephrin receptor A2 is an epithelial cell receptor for Epstein-Barr virus entry., PMID:29292383

Inhibition of EBV-mediated membrane fusion by anti-gHgL antibodies., PMID:28939750

Structural basis for potent antibody-mediated neutralization of human cytomegalovirus., PMID:28783665

Efficient evaluation of humoral immune responses by the use of serum pools., PMID:28130033

Structural basis for Epstein-Barr virus host cell tropism mediated by gp42 and gHgL entry glycoproteins., PMID:27929061

Novel Epstein-Barr virus-like particles incorporating gH/gL-EBNA1 or gB-LMP2 induce high neutralizing antibody titers and EBV-specific T-cell responses in immunized mice., PMID:27926486

Rabbits immunized with Epstein-Barr virus gH/gL or gB recombinant proteins elicit higher serum virus neutralizing activity than gp350., PMID:27291087

Epstein-Barr virus glycoprotein gH/gL antibodies complement IgA-viral capsid antigen for diagnosis of nasopharyngeal carcinoma., PMID:27093005

Application of synthetic peptides for detection of anti-citrullinated peptide antibodies., PMID:26796582

Scanning Mutagenesis of Human Cytomegalovirus Glycoprotein gH/gL., PMID:26656708

Isolation, production and characterization of fully human monoclonal antibodies directed to Plasmodium falciparum MSP10., PMID:26174014

Human Cytomegalovirus gH/gL/gO Promotes the Fusion Step of Entry into All Cell Types, whereas gH/gL/UL128-131 Broadens Virus Tropism through a Distinct Mechanism., PMID:26085146

The different clinical effects of anti-BLyS, anti-APRIL and anti-CD20 antibodies point at a critical pathogenic role of γ-herpesvirus infected B cells in the marmoset EAE model., PMID:23508625

Herpes virus fusion and entry: a story with many characters., PMID:22754650

Fusion of Epstein-Barr virus with epithelial cells can be triggered by αvβ5 in addition to αvβ6 and αvβ8, and integrin binding triggers a conformational change in glycoproteins gHgL., PMID:21957301

Structure of a core fragment of glycoprotein H from pseudorabies virus in complex with antibody., PMID:21149698

α-Helix peptides designed from EBV-gH protein display higher antigenicity and induction of monocyte apoptosis than the native peptide., PMID:20473772

Fusion of epithelial cells by Epstein-Barr virus proteins is triggered by binding of viral glycoproteins gHgL to integrins alphavbeta6 or alphavbeta8., PMID:19920174

Point mutations in EBV gH that abrogate or differentially affect B cell and epithelial cell fusion., PMID:17307213

Mutations of Epstein-Barr virus gH that are differentially able to support fusion with B cells or epithelial cells., PMID:16103144

Datasheet
$ 372
Product specifications
100 μg 372 1 mg 1860

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For research use only. Not for human or drug use.

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Anti-EBV/HHV-4 gH/BXLF2 Antibody (CL40) [RVV15101]
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