Catalog No.
RHC10001
Species reactivity
Human
Host species
Mouse
Isotype
IgG2a, kappa
Clonality
Monoclonal
Target
Antigen NY-CO-13, Cellular tumor antigen p53, P53, Tumor suppressor p53, TP53, Phosphoprotein p53
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P04637
Applications
IHC, IP, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
23#
A tailored phospho-p53 library probes antibody specificity and recognition limitations., PMID:40418670
An 8-aminoquinoline-naphthyl copper complex causes apoptotic cell death by modulating the expression of apoptotic regulatory proteins in breast cancer cells., PMID:38908670
Integrated immunochromatographic strip with glucometer readout for rapid quantification of phosphorylated proteins., PMID:28351626
MG132 plus apoptosis antigen-1 (APO-1) antibody cooperate to restore p53 activity inducing autophagy and p53-dependent apoptosis in HPV16 E6-expressing keratinocytes., PMID:27766434
Simultaneous immunoassay of phosphorylated proteins based on apoferritin templated metallic phosphates as voltammetrically distinguishable signal reporters., PMID:26844908
Obesity-induced p53 activation in insulin-dependent and independent tissues is inhibited by beta-adrenergic agonist in diet-induced obese rats., PMID:26827989
Glucose encapsulating liposome for signal amplification for quantitative detection of biomarkers with glucometer readout., PMID:26005847
DNA microarray and signal transduction analysis in pulmonary artery smooth muscle cells from heritable and idiopathic pulmonary arterial hypertension subjects., PMID:25290246
Combination of AT-101/cisplatin overcomes chemoresistance by inducing apoptosis and modulating epigenetics in human ovarian cancer cells., PMID:23269627
CCR5 plays an important role in resolving an inflammatory response to single-walled carbon nanotubes., PMID:22438032
Increased cell apoptosis of urothelium mediated by inflammation in interstitial cystitis/painful bladder syndrome., PMID:22310775
The E3 ubiquitin ligase Mule acts through the ATM-p53 axis to maintain B lymphocyte homeostasis., PMID:22213803
p53-regulated increase in oxidative-stress--induced apoptosis in Fuchs endothelial corneal dystrophy: a native tissue model., PMID:22064994
Multiplexed electrochemical immunoassay of phosphorylated proteins based on enzyme-functionalized gold nanorod labels and electric field-driven acceleration., PMID:21797208
Graphene-based immunosensor for electrochemical quantification of phosphorylated p53 (S15)., PMID:21704756
Apoptosis occurs differentially according to glomerular size in diabetic kidney disease., PMID:21652547
Functionalized graphene oxide as a nanocarrier in a multienzyme labeling amplification strategy for ultrasensitive electrochemical immunoassay of phosphorylated p53 (S392)., PMID:21210663
Synergistic effects of topoisomerase I inhibitor, SN38, on Fas-mediated apoptosis., PMID:21036702
Signaling pathways implicated in PGF2alpha effects on Fgf2+/+ and Fgf2-/- osteoblasts., PMID:20432442
A novel function for p53: regulation of growth cone motility through interaction with Rho kinase., PMID:19386914
Expression of Arl2 is associated with p53 localization and chemosensitivity in a breast cancer cell line., PMID:18818514
Genetic and epigenetic alterations in lung tumors from bitransgenic Ki-rasG12C expressing mice., PMID:16482519
Phosphorylation of histone H2AX at M phase in human cells without DNA damage response., PMID:16153602
Survivin and p53 modulate quercetin-induced cell growth inhibition and apoptosis in human lung carcinoma cells., PMID:15456784
Dual and opposing roles of ERK in regulating G(1) and S-G(2)/M delays in A549 cells caused by hyperoxia., PMID:15212949
Low levels of glutathione peroxidase 1 activity in selenium-deficient mouse liver affect c-Jun N-terminal kinase activation and p53 phosphorylation on Ser-15 in pro-oxidant-induced aponecrosis., PMID:12492400
The processing of Holliday junctions by BLM and WRN helicases is regulated by p53., PMID:12080066